PRD_000444
概要
名称: | methyl N-[(2S)-4-{[(1S)-1-{[(2S)-2-carboxypyrrolidin-1-yl]carbonyl}-3-methylbutyl]amino}-2-hydroxy-4-oxobutanoyl]-L-leucylglycylglycinate |
別名: | NS-134 |
組成式: | C26 H41 N5 O10 |
電荷: | 0 |
化学式量: | 583.631 |
分子種別: | peptide-like |
ポリマー配列: | MEU, GLY, LEU, EPO, LEU, PRO |
非ポリマー要素: | |
BIRDクラス: | Inhibitor |
PDB中の表現: | single molecule |
Families: | FAM_000317 |
プログラム | バージョン | 表記 |
ACDLabs | 10.04 | methyl N-{[(2S,3S)-3-{[(1S)-1-{[(2S)-2-carboxypyrrolidin-1-yl]carbonyl}-3-methylbutyl]carbamoyl}oxiran-2-yl]carbonyl}-L-leucylglycylglycinate |
OpenEye OEToolkits | 1.5.0 | (2S)-1-[(2S)-2-[[(2S,3S)-3-[[(2S)-1-[[2-[(2-methoxy-2-oxo-ethyl)amino]-2-oxo-ethyl]amino]-4-methyl-1-oxo-pentan-2-yl]carbamoyl]oxiran-2-yl]carbonylamino]-4-methyl-pentanoyl]pyrrolidine-2-carboxylic acid |
化合物記述子(線形表記)
種別 | プログラム | バージョン | 表記 |
SMILES | ACDLabs | 10.04 | O=C(NC(C(=O)N1C(C(=O)O)CCC1)CC(C)C)C2OC2C(=O)NC(C(=O)NCC(=O)NCC(=O)OC)CC(C)C |
SMILES_CANONICAL | CACTVS | 3.341 | COC(=O)CNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(O)=O |
SMILES | CACTVS | 3.341 | COC(=O)CNC(=O)CNC(=O)[CH](CC(C)C)NC(=O)[CH]1O[CH]1C(=O)N[CH](CC(C)C)C(=O)N2CCC[CH]2C(O)=O |
SMILES_CANONICAL | OpenEye OEToolkits | 1.5.0 | CC(C)C[C@@H](C(=O)NCC(=O)NCC(=O)OC)NC(=O)[C@@H]1[C@H](O1)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)O |
SMILES | OpenEye OEToolkits | 1.5.0 | CC(C)CC(C(=O)NCC(=O)NCC(=O)OC)NC(=O)C1C(O1)C(=O)NC(CC(C)C)C(=O)N2CCCC2C(=O)O |
InChI | InChI | 1.03 | InChI=1S/C26H41N5O10/c1-13(2)9-15(22(34)28-11-18(32)27-12-19(33)40-5)29-23(35)20-21(41-20)24(36)30-16(10-14(3)4)25(37)31-8-6-7-17(31)26(38)39/h13-17,20-21H,6-12H2,1-5H3,(H,27,32)(H,28,34)(H,29,35)(H,30,36)(H,38,39)/t15-,16-,17-,20-,21-/m0/s1 |
InChIKey | InChI | 1.03 | LLLKOFOBLVPXQZ-RNEDXHKXSA-N |