PDB: 278 resultsInfo pagesStatus searchChemie searchBIRD

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7OOH	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 Descriptor: 4-IODOPYRAZOLE, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... Authors: Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. Deposit date: 2021-05-27 Release date: 2021-06-09 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 To Be Published
7O6R	Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with 1H-Indazole Descriptor: 1H-indazole, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... Authors: Zehe, M, Grimm, C, Sotriffer, C. Deposit date: 2021-04-12 Release date: 2022-05-04 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. Acs Chem.Biol., 2024
7ODI	Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with methanesulfonamide Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Heat shock cognate 71 kDa protein, ... Authors: Zehe, M, Grimm, C, Sotriffer, C. Deposit date: 2021-04-29 Release date: 2022-06-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. Acs Chem.Biol., 2024
7ODD	Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with tricine Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Heat shock cognate 71 kDa protein, ... Authors: Zehe, M, Grimm, C, Sotriffer, C. Deposit date: 2021-04-29 Release date: 2022-06-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.984 Å) Cite: Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. Acs Chem.Biol., 2024
7ODB	Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with triazine-derivative Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-methyl-5-sulfanylidene-2H-1,2,4-triazin-3-one, GLYCEROL, ... Authors: Zehe, M, Grimm, C, Sotriffer, C. Deposit date: 2021-04-29 Release date: 2022-06-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.662 Å) Cite: Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. Acs Chem.Biol., 2024
7P31	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 Descriptor: 4-IODOPYRAZOLE, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... Authors: Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. Deposit date: 2021-07-06 Release date: 2021-07-14 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with small molecule ligands To Be Published
4EZP	Crystal structure of the substrate binding domain of E.coli DnaK in complex with A3-APO(residues 1 to 20) Descriptor: APO-monomer, Chaperone protein DnaK, SULFATE ION Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4F01	Crystal structure of an artificial dimeric DnaK complex Descriptor: Chaperone protein DnaK Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZT	Crystal structure of the substrate binding domain of E.coli DnaK in complex with heliocin (residues 14 to 21) Descriptor: Chaperone protein DnaK, Heliocin Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZR	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the C-terminal part of drosocin (residues 12 to 19) Descriptor: Chaperone protein DnaK, Drosocin Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZW	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide NRLLLTG Descriptor: Chaperone protein DnaK, SULFATE ION, synthetic peptide NRLLLTG Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZO	Crystal structure of the substrate binding domain of E.coli DnaK in complex with PR-39 (residues 1 to 15) Descriptor: Antibacterial protein PR-39, Chaperone protein DnaK, SULFATE ION Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZZ	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide ELPLVKI Descriptor: Chaperone protein DnaK, synthetic peptide ELPLVKI Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZQ	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the C-terminal part of pyrrhocoricin (residues 12 to 20) Descriptor: Chaperone protein DnaK, Pyrrhocoricin Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZS	Crystal structure of the substrate binding domain of E.coli DnaK in complex with metchnikowin (residues 20 to 26) Descriptor: Chaperone protein DnaK, Metchnikowin, SULFATE ION Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural studies of DnaK in complex with proline rich antimicrobial peptides reveal two different peptide binding modes To be Published
4EZY	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide NRLILTG Descriptor: Chaperone protein DnaK, SULFATE ION, synthetic peptide NRLILTG Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZN	Crystal structure of the substrate binding domain of E.coli DnaK in complex with pyrrhocoricin Descriptor: Chaperone protein DnaK, Pyrrhocoricin Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZX	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide NRLMLTG Descriptor: Chaperone protein DnaK, SULFATE ION, synthetic peptide NRLMLTG Authors: Zahn, M, Straeter, N. Deposit date: 2012-05-03 Release date: 2013-04-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4FL9	Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Heat shock cognate 71 kDa protein, trimethylamine oxide Authors: Grimm, C. Deposit date: 2012-06-14 Release date: 2013-10-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.901 Å) Cite: Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution TO BE PUBLISHED
4FSV	Crystal structure of a heat shock 70kDa protein 2 (HSPA2) from Homo sapiens at 1.80 A resolution Descriptor: Heat shock-related 70 kDa protein 2 Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) Deposit date: 2012-06-27 Release date: 2012-07-18 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of a heat shock 70kDa protein 2 (HSPA2) from Homo sapiens at 1.80 A resolution To be published
4H5T	HSC70 NBD with ADP and Mg Descriptor: ADENOSINE-5'-DIPHOSPHATE, Heat shock cognate 71 kDa protein, MAGNESIUM ION, ... Authors: Stec, B. Deposit date: 2012-09-18 Release date: 2014-03-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
4H5N	HSC70 NBD with PO4, Na, Cl Descriptor: CHLORIDE ION, GLYCEROL, Heat shock cognate 71 kDa protein, ... Authors: Stec, B. Deposit date: 2012-09-18 Release date: 2014-03-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.86 Å) Cite: New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
4H5W	HSC70 NBD with betaine Descriptor: ACETATE ION, Heat shock cognate 71 kDa protein, MAGNESIUM ION, ... Authors: Stec, B. Deposit date: 2012-09-19 Release date: 2014-03-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.94 Å) Cite: New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
4GNI	Structure of the Ssz1 ATPase bound to ATP and Magnesium Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative heat shock protein Authors: Bange, G, Sinning, I. Deposit date: 2012-08-17 Release date: 2012-12-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.796 Å) Cite: Structural characterization of a eukaryotic chaperone-the ribosome-associated complex. Nat.Struct.Mol.Biol., 20, 2013
4H5V	HSC70 NBD with Mg Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ... Authors: Stec, B. Deposit date: 2012-09-18 Release date: 2014-03-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015

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