7CAX
 
 | | Crystal structure of bacterial reductase | | Descriptor: | 1,2-ETHANEDIOL, 3-oxoacyl-ACP reductase FabG, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Kim, Y, Lee, W.C. | | Deposit date: | 2020-06-10 | | Release date: | 2021-06-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.846 Å) | | Cite: | Crystal structure of bacterial reductase
To be published
|
|
7DZV
 | |
7DZT
 | | Cyrstal structure of PETase from Rhizobacter gummiphilus | | Descriptor: | DLH domain-containing protein | | Authors: | Sagong, H.-Y, Kim, K.-J. | | Deposit date: | 2021-01-26 | | Release date: | 2021-07-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Implications for the PET decomposition mechanism through similarity and dissimilarity between PETases from Rhizobacter gummiphilus and Ideonella sakaiensis.
J Hazard Mater, 416, 2021
|
|
7DZU
 | |
7ETY
 | |
7ETX
 | |
6JJL
 | | Crystal structure of the DegP dodecamer with a modulator | | Descriptor: | CYS-TYR-ARG-LYS-LEU, Periplasmic serine endoprotease DegP | | Authors: | Cho, H, Choi, Y, Lee, H.H, Kim, S. | | Deposit date: | 2019-02-26 | | Release date: | 2020-09-02 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (4.2 Å) | | Cite: | Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy.
Commun Biol, 3, 2020
|
|
6JJK
 | | Crystal structure of the DegP dodecamer with a modulator | | Descriptor: | CYS-TYR-TYR-LYS-ILE, Periplasmic serine endoprotease DegP | | Authors: | Cho, H, Choi, Y, Lee, H.H, Kim, S. | | Deposit date: | 2019-02-26 | | Release date: | 2020-09-02 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy
Commun Biol, 3, 2020
|
|
6JJO
 | | Crystal structure of the DegP dodecamer with a modulator | | Descriptor: | Periplasmic serine endoprotease DegP, TMB-CYRKL modulator | | Authors: | Cho, H, Choi, Y, Lee, H.H, Kim, S. | | Deposit date: | 2019-02-26 | | Release date: | 2020-09-02 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (4.157 Å) | | Cite: | Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy
Commun Biol, 3, 2020
|
|
6JTT
 | | MHETase in complex with BHET | | Descriptor: | 4-(2-hydroxyethyloxycarbonyl)benzoic acid, CALCIUM ION, Mono(2-hydroxyethyl) terephthalate hydrolase, ... | | Authors: | Sagong, H.-Y, Seo, H, Kim, K.-J. | | Deposit date: | 2019-04-12 | | Release date: | 2020-04-15 | | Last modified: | 2020-10-28 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Decomposition of PET film by MHETase using Exo-PETase function
Acs Catalysis, 10, 2020
|
|
6JTU
 | | Crystal structure of MHETase from Ideonella sakaiensis | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | | Authors: | Sagong, H.-Y, Seo, H, Kim, K.-J. | | Deposit date: | 2019-04-12 | | Release date: | 2020-04-15 | | Last modified: | 2020-10-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Decomposition of PET film by MHETase using Exo-PETase function
Acs Catalysis, 10, 2020
|
|
6KX8
 | | Crystal structure of mouse Cryptochrome 2 in complex with TH301 compound | | Descriptor: | 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-2 | | Authors: | Miller, S.A, Aikawa, Y, Hirota, T. | | Deposit date: | 2019-09-10 | | Release date: | 2020-04-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
|
|
6KX7
 | | Crystal structure of mouse Cryptochrome 1 in complex with TH301 compound | | Descriptor: | 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-1 | | Authors: | Miller, S.A, Aikawa, Y, Hirota, T. | | Deposit date: | 2019-09-10 | | Release date: | 2020-04-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
|
|
6KX5
 | |
6KX6
 | | Crystal structure of mouse Cryptochrome 1 in complex with KL101 compound | | Descriptor: | Cryptochrome-1, ~{N}-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl-benzamide | | Authors: | Miller, S.A, Aikawa, Y, Hirota, T. | | Deposit date: | 2019-09-10 | | Release date: | 2020-04-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
|
|
6KX4
 | |
6MNX
 | |
6AIY
 | |
6AKV
 | | Crystal structure of LysB4, the endolysin from Bacillus cereus-targeting bacteriophage B4 | | Descriptor: | CHLORIDE ION, LysB4, SULFATE ION, ... | | Authors: | Hong, S, Ha, N.-C. | | Deposit date: | 2018-09-03 | | Release date: | 2019-02-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of LysB4, an Endolysin fromBacillus cereus-Targeting Bacteriophage B4.
Mol. Cells, 42, 2019
|
|
6AIX
 | |
6BVJ
 | | Ras:SOS:Ras in complex with a small molecule activator | | Descriptor: | 5-chloro-N-{1-[(5-chloro-1H-indol-3-yl)methyl]piperidin-4-yl}-L-tryptophanamide, FORMIC ACID, GLYCEROL, ... | | Authors: | Phan, J, Abbott, J, Fesik, S.W. | | Deposit date: | 2017-12-13 | | Release date: | 2018-10-24 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.747 Å) | | Cite: | Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling.
J. Med. Chem., 61, 2018
|
|
6BVL
 | | Ras:SOS:Ras in complex with a small molecule activator | | Descriptor: | FORMIC ACID, GLYCEROL, GTPase HRAS, ... | | Authors: | Phan, J, Abbott, J, Fesik, S.W. | | Deposit date: | 2017-12-13 | | Release date: | 2018-10-24 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.748 Å) | | Cite: | Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling.
J. Med. Chem., 61, 2018
|
|
6BVM
 | | Ras:SOS:Ras in complex with a small molecule activator | | Descriptor: | (2S)-2-amino-1-[(3aR,6aS)-5-[(5-chloro-1H-indol-3-yl)methyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-3-(1H-indol-3-yl)propan-1-one, FORMIC ACID, GLYCEROL, ... | | Authors: | Phan, J, Abbott, J, Fesik, S.W. | | Deposit date: | 2017-12-13 | | Release date: | 2018-10-24 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.796 Å) | | Cite: | Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling.
J. Med. Chem., 61, 2018
|
|
6BVI
 | | Ras:SOS:Ras in complex with a small molecule activator | | Descriptor: | 6-chloro-N-{1-[(5-chloro-1H-indol-3-yl)methyl]piperidin-4-yl}-L-tryptophanamide, FORMIC ACID, GLYCEROL, ... | | Authors: | Phan, J, Abbott, J, Fesik, S.W. | | Deposit date: | 2017-12-13 | | Release date: | 2018-10-24 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.746 Å) | | Cite: | Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling.
J. Med. Chem., 61, 2018
|
|
6CUP
 | | Ras:SOS:Ras in complex with a small molecule activator | | Descriptor: | FORMIC ACID, GLYCEROL, GTPase HRas, ... | | Authors: | Phan, J, Abbott, J, Fesik, S.W. | | Deposit date: | 2018-03-26 | | Release date: | 2019-02-06 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.833 Å) | | Cite: | Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS.
ACS Med Chem Lett, 9, 2018
|
|
