6RS0
 
 | | GOLGI ALPHA-MANNOSIDASE II in complex with (2S,3S,4R,5R)-1-(2-(Benzyloxy)ethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol | | Descriptor: | (2~{S},3~{S},4~{R})-2-(hydroxymethyl)-1-(2-phenylmethoxyethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, Alpha-mannosidase 2, ... | | Authors: | Armstrong, Z, Lahav, D, Johnson, R, Kuo, C.L, Beenakker, T.J.M, de Boer, C, Wong, C.S, van Rijssel, E.R, Debets, M, Geurink, P.P, Ovaa, H, van der Stelt, M, Codee, J.D.C, Aerts, J.M.F.G, Wu, L, Overkleeft, H.S, Davies, G.J. | | Deposit date: | 2019-05-20 | | Release date: | 2020-07-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Manno- epi -cyclophellitols Enable Activity-Based Protein Profiling of Human alpha-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors.
J.Am.Chem.Soc., 142, 2020
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7DD9
 | | Cryo-EM structure of the Ams1 and Nbr1 complex | | Descriptor: | Alpha-mannosidase,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION | | Authors: | Zhang, J, Ye, K. | | Deposit date: | 2020-10-28 | | Release date: | 2021-07-14 | | Last modified: | 2021-08-11 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Embo J., 40, 2021
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7UFR
 | | Cryo-EM Structure of Bl_Man38A at 2.7 A | | Descriptor: | Alpha-mannosidase, ZINC ION | | Authors: | Santos, C.R, Cordeiro, R.L, Domingues, M.N, Borges, A.C, de Farias, M.A, Van Heel, M, Murakami, M.T, Portugal, R.V. | | Deposit date: | 2022-03-23 | | Release date: | 2022-11-16 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Cryo-EM Structure of Bl_Man38A at 2.7 A
Nat.Chem.Biol., 2022
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7UFS
 | | Cryo-EM Structure of Bl_Man38B at 3.4 A | | Descriptor: | Alpha-mannosidase, ZINC ION | | Authors: | Santos, C.R, Cordeiro, R.L, Domingues, M.N, Borges, A.C, de Farias, M.A, Van Heel, M, Murakami, M.T, Portugal, R.V. | | Deposit date: | 2022-03-23 | | Release date: | 2022-11-16 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM Structure of Bl_Man38B at 3.4 A
Nat.Chem.Biol., 2022
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7UFT
 | | Cryo-EM Structure of Bl_Man38C at 2.9 A | | Descriptor: | Alpha-mannosidase, ZINC ION | | Authors: | Santos, C.R, Cordeiro, R.L, Domingues, M.N, Borges, A.C, de Farias, M.A, Van Heel, M, Murakami, M.T, Portugal, R.V. | | Deposit date: | 2022-03-23 | | Release date: | 2022-11-16 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Cryo-EM Structure of Bl_Man38C at 2.9 A
Nat.Chem.Biol., 2022
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7UFU
 | | Cryo-EM Structure of Bl_Man38A nucleophile mutant in complex with mannose at 2.7 A | | Descriptor: | Alpha-mannosidase, ZINC ION, alpha-D-mannopyranose | | Authors: | Santos, C.R, Cordeiro, R.L, Domingues, M.N, Borges, A.C, de Farias, M.A, Van Heel, M, Murakami, M.T, Portugal, R.V. | | Deposit date: | 2022-03-23 | | Release date: | 2022-11-16 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Cryo-EM Structure of Bl_Man38A nucleophile mutant in complex with mannose at 2.7 A
Nat.Chem.Biol., 2022
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7VQO
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