6UXA
 
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6UX7
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6UX4
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6UWN
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6UFE
 | | The structure of a potassium selective ion channel at atomic resolution | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Transporter | | Authors: | Langan, P.S, Vandavasi, V.G, Sullivan, B, Afonine, P.V, Weiss, K.L. | | Deposit date: | 2019-09-24 | | Release date: | 2020-08-05 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | The structure of a potassium-selective ion channel reveals a hydrophobic gate regulating ion permeation.
Iucrj, 7, 2020
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6U9T
 | | Wild-type MthK pore in 50 mM K+ | | Descriptor: | Calcium-gated potassium channel MthK, HEXANE-1,6-DIOL, POTASSIUM ION | | Authors: | Posson, D.J, Nimigean, C.M. | | Deposit date: | 2019-09-09 | | Release date: | 2020-11-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Selectivity filter ion binding affinity determines inactivation in a potassium channel.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6U9P
 | | Wild-type MthK pore in ~150 mM K+ | | Descriptor: | Calcium-gated potassium channel MthK, HEXANE-1,6-DIOL, POTASSIUM ION | | Authors: | Posson, D.J, Nimigean, C.M. | | Deposit date: | 2019-09-09 | | Release date: | 2020-11-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Selectivity filter ion binding affinity determines inactivation in a potassium channel.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6U9Z
 | | Wild-type MthK pore in 6 mM K+ | | Descriptor: | Calcium-gated potassium channel MthK, HEXANE-1,6-DIOL, POTASSIUM ION | | Authors: | Posson, D.J, Nimigean, C.M. | | Deposit date: | 2019-09-09 | | Release date: | 2020-11-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.954 Å) | | Cite: | Selectivity filter ion binding affinity determines inactivation in a potassium channel.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6U9Y
 | | Wild-type MthK pore in 11 mM K+ | | Descriptor: | Calcium-gated potassium channel MthK, HEXANE-1,6-DIOL, POTASSIUM ION | | Authors: | Posson, D.J, Nimigean, C.M. | | Deposit date: | 2019-09-09 | | Release date: | 2020-11-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Selectivity filter ion binding affinity determines inactivation in a potassium channel.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6U6H
 | | Calcium-bound MthK open-inactivated state 3 | | Descriptor: | Calcium-gated potassium channel MthK | | Authors: | Chen, F, Crina, N. | | Deposit date: | 2019-08-29 | | Release date: | 2020-04-22 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel.
Nature, 580, 2020
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6U68
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6U6E
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6U6D
 | | MthK closed state with EDTA | | Descriptor: | Calcium-gated potassium channel MthK, POTASSIUM ION | | Authors: | Fan, C, Rheinberger, J, Nimigean, C.M. | | Deposit date: | 2019-08-29 | | Release date: | 2020-03-25 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel.
Nature, 580, 2020
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6U5R
 | | Calcium-bound MthK closed state | | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | | Authors: | Fan, C, Nimigean, C.M. | | Deposit date: | 2019-08-28 | | Release date: | 2020-03-25 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel.
Nature, 580, 2020
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6U5P
 | | Calcium-bound MthK gating ring state 1 | | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | | Authors: | Fan, C, Nimigean, C.M. | | Deposit date: | 2019-08-28 | | Release date: | 2020-03-25 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel.
Nature, 580, 2020
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6U5N
 | | Calcium-bound MthK gating ring state 2 | | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | | Authors: | Fan, C, Nimigean, C.M. | | Deposit date: | 2019-08-28 | | Release date: | 2020-03-25 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel.
Nature, 580, 2020
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6PIS
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6PA0
 | | Structure of the G77A mutant in Sodium Chloride | | Descriptor: | Antibody HEAVY fragment, Antibody LIGHT fragment, DIACYL GLYCEROL, ... | | Authors: | Cuello, L.G, Guan, L. | | Deposit date: | 2019-06-11 | | Release date: | 2019-08-07 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6RV3
 | | Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation with a bound inhibitor BAY 1000493 | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DECYL-BETA-D-MALTOPYRANOSIDE, ... | | Authors: | Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | Deposit date: | 2019-05-30 | | Release date: | 2019-08-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | A lower X-gate in TASK channels traps inhibitors within the vestibule.
Nature, 582, 2020
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6RV4
 | | Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation with a bound inhibitor BAY 2341237 | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, ... | | Authors: | Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | Deposit date: | 2019-05-30 | | Release date: | 2019-08-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | A lower X-gate in TASK channels traps inhibitors within the vestibule.
Nature, 582, 2020
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6RV2
 | | Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DECYL-BETA-D-MALTOPYRANOSIDE, ... | | Authors: | Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | Deposit date: | 2019-05-30 | | Release date: | 2019-08-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | A lower X-gate in TASK channels traps inhibitors within the vestibule.
Nature, 582, 2020
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6OLY
 | | Full-length MthK channel at 3.1 angstrom resolution | | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | | Authors: | Rothberg, B.S. | | Deposit date: | 2019-04-17 | | Release date: | 2019-12-11 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.112 Å) | | Cite: | Molecular mechanism of a potassium channel gating through activation gate-selectivity filter coupling.
Nat Commun, 10, 2019
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6O9U
 | | KirBac3.1 at a resolution of 2 Angstroms | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3,3',3''-phosphoryltripropanoic acid, BARIUM ION, ... | | Authors: | Gulbis, J.M, Clarke, O.B. | | Deposit date: | 2019-03-15 | | Release date: | 2020-05-27 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A constricted opening in Kir channels does not impede potassium conduction.
Nat Commun, 11, 2020
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6O9T
 | | KirBac3.1 mutant at a resolution of 4.1 Angstroms | | Descriptor: | 2,3,5,6-tetramethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione, Inward rectifier potassium channel Kirbac3.1, POTASSIUM ION | | Authors: | Gulbis, J.M, Black, K.A, Miller, D.M. | | Deposit date: | 2019-03-15 | | Release date: | 2020-05-27 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (4.01 Å) | | Cite: | A constricted opening in Kir channels does not impede potassium conduction.
Nat Commun, 11, 2020
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6O9V
 | | KirBac3.1 mutant at a resolution of 3.1 Angstroms | | Descriptor: | 1,1-Methanediyl Bismethanethiosulfonate, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, Inward rectifier potassium channel Kirbac3.1, ... | | Authors: | Gulbis, J.M, Black, K.A, Miller, D.M. | | Deposit date: | 2019-03-15 | | Release date: | 2020-05-27 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.094 Å) | | Cite: | A constricted opening in Kir channels does not impede potassium conduction.
Nat Commun, 11, 2020
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