PDB: 1344 resultsInfo pagesStatus searchChemie searchBIRD

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5J5B	Structure of the WT E coli ribosome bound to tetracycline Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... Authors: Cocozaki, A, Ferguson, A. Deposit date: 2016-04-01 Release date: 2016-07-27 Last modified: 2018-08-15 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
8G2D	Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with tylosin, mRNA, deacylated A- and E-site tRNAphe, and deacylated P-site tRNAmet at 2.70A resolution Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Aleksandrova, E.V, Wu, K.J.Y, Tresco, B.I.C, Syroegin, E.A, Killeavy, E.E, Balasanyants, S.M, Svetlov, M.S, Gregory, S.T, Atkinson, G.C, Myers, A.G, Polikanov, Y.S. Deposit date: 2023-02-03 Release date: 2023-12-27 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it. Nat.Chem.Biol., 2024
8G2A	Crystal structure of the A2503-C2,C8-dimethylated Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-tRNAphe, peptidyl P-site fMTHSMRC-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Aleksandrova, E.V, Wu, K.J.Y, Tresco, B.I.C, Syroegin, E.A, Killeavy, E.E, Balasanyants, S.M, Svetlov, M.S, Gregory, S.T, Atkinson, G.C, Myers, A.G, Polikanov, Y.S. Deposit date: 2023-02-03 Release date: 2023-12-27 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it. Nat.Chem.Biol., 2024
8G2C	Crystal structure of the A2503-C2,C8-dimethylated Thermus thermophilus 70S ribosome in complex with tylosin, mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.65A resolution Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Aleksandrova, E.V, Wu, K.J.Y, Tresco, B.I.C, Syroegin, E.A, Killeavy, E.E, Balasanyants, S.M, Svetlov, M.S, Gregory, S.T, Atkinson, G.C, Myers, A.G, Polikanov, Y.S. Deposit date: 2023-02-03 Release date: 2023-12-27 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it. Nat.Chem.Biol., 2024
8G2B	Crystal structure of the A2503-C2,C8-dimethylated Thermus thermophilus 70S ribosome in complex with iboxamycin, mRNA, deacylated A- and E-site tRNAphe, and aminoacylated P-site fMet-tRNAmet at 2.55A resolution Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Aleksandrova, E.V, Wu, K.J.Y, Tresco, B.I.C, Syroegin, E.A, Killeavy, E.E, Balasanyants, S.M, Svetlov, M.S, Gregory, S.T, Atkinson, G.C, Myers, A.G, Polikanov, Y.S. Deposit date: 2023-02-03 Release date: 2023-12-27 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it. Nat.Chem.Biol., 2024
8G29	Crystal structure of the A2503-C2,C8-dimethylated Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.55A resolution Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Aleksandrova, E.V, Wu, K.J.Y, Tresco, B.I.C, Syroegin, E.A, Killeavy, E.E, Balasanyants, S.M, Svetlov, M.S, Gregory, S.T, Atkinson, G.C, Myers, A.G, Polikanov, Y.S. Deposit date: 2023-02-03 Release date: 2023-12-27 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it. Nat.Chem.Biol., 2024
8G7Q	Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the near-cognate AUG codon (Structure II) Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rybak, M.Y, Gagnon, M.G. Deposit date: 2023-02-16 Release date: 2024-03-06 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance. Nat.Struct.Mol.Biol., 2024
8G7R	Structure of the Escherichia coli 70S ribosome in complex with A-site tRNAIle(LAU) bound to the cognate AUA codon (Structure III) Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rybak, M.Y, Gagnon, M.G. Deposit date: 2023-02-16 Release date: 2024-03-06 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance. Nat.Struct.Mol.Biol., 2024
8G7P	Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the cognate AUA codon (Structure I) Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rybak, M.Y, Gagnon, M.G. Deposit date: 2023-02-16 Release date: 2024-03-06 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance. Nat.Struct.Mol.Biol., 2024
8G7S	Structure of the Escherichia coli 70S ribosome in complex with P-site tRNAIle(LAU) bound to the cognate AUA codon (Structure IV) Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rybak, M.Y, Gagnon, M.G. Deposit date: 2023-02-16 Release date: 2024-03-06 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structures of the ribosome bound to EF-Tu-isoleucine tRNA elucidate the mechanism of AUG avoidance. Nat.Struct.Mol.Biol., 2024
8GHU	Methyltransferase RmtC bound to the 30S ribosomal subunit Descriptor: 16S rRNA, 16S rRNA (guanine(1405)-N(7))-methyltransferase, 30S ribosomal protein S12, ... Authors: Srinivas, P, Conn, G.L, Dunham, C.M. Deposit date: 2023-03-12 Release date: 2023-04-12 Method: ELECTRON MICROSCOPY (3 Å) Cite: 30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. Biorxiv, 2023
8GLP	mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... Authors: Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. Deposit date: 2023-03-22 Release date: 2023-04-19 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (1.67 Å) Cite: mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8HL1	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 16s rRNA (1493-MER), 23s rRNA (3000-MER), 30S ribosomal protein S10, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (3.93 Å) Cite: Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome. Nucleic Acids Res., 51, 2023
8HKX	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 16s rRNA (1491-MER), 30S ribosomal protein, 30S ribosomal protein S10, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-08-16 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome To Be Published
8HKZ	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 16S rRNA (1493-MER), 23S rRNA (2996-MER), 30S ribosomal protein S10, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-08-30 Last modified: 2023-10-11 Method: ELECTRON MICROSCOPY (4.78 Å) Cite: Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome. Nucleic Acids Res., 51, 2023
8HKY	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-08-30 Method: ELECTRON MICROSCOPY (4.45 Å) Cite: Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome To Be Published
8HL3	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 16s rRNA (1493-MER), 23s rRNA (3000-MER), 30S ribosomal protein S10, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-09-20 Last modified: 2024-04-03 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome. Nucleic Acids Res., 51, 2023
8HL2	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 16s rRNA (1493-MER), 23s rRNA (3000-MER), 30S ribosomal protein S10, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-09-20 Last modified: 2024-04-03 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome. Nucleic Acids Res., 51, 2023
8HL5	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 16S rRNA (1493-MER), 23S rRNA (2991-MER), 30S ribosomal protein S10, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-10-04 Method: ELECTRON MICROSCOPY (5.72 Å) Cite: Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome To Be Published
8HL4	Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome Descriptor: 16s rRNA (1493-MER), 23s rRNA (3000-MER), 30S ribosomal protein S10, ... Authors: Wang, Y.H, Zhou, J. Deposit date: 2022-11-28 Release date: 2023-11-29 Method: ELECTRON MICROSCOPY (4.62 Å) Cite: Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome To Be Published
8I7J	Yeast 40S-eIF4B - partially open conformation of the 40S head Descriptor: 40S ribosomal protein S0, 40S ribosomal protein S1, 40S ribosomal protein S12, ... Authors: Datey, A, Khaja, F.T, Hussain, T. Deposit date: 2023-01-31 Release date: 2024-02-07 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Yeast eukaryotic initiation factor 4B remodels the mRNA entry site on the small ribosomal subunit To Be Published
8HSP	E. coli 70S ribosome complexed with tRNA_Ile2 bearing L34 and t6A37 in classical state Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. Deposit date: 2022-12-20 Release date: 2024-04-03 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (2.32 Å) Cite: Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 2024
8HU1	E. coli 70S ribosome complexed with tRNA_Ile2 bearing L34 and ct6A37 in classical state Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. Deposit date: 2022-12-22 Release date: 2024-04-03 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (2.69 Å) Cite: Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 2024
8HTZ	E. coli 70S ribosome complexed with H. marismortui tRNA_Ile2 bearing agm2C34 in classical state Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... Authors: Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. Deposit date: 2022-12-22 Release date: 2024-04-03 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 2024
8IFD	Dibekacin-added human 80S ribosome Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. Deposit date: 2023-02-17 Release date: 2024-02-14 Method: ELECTRON MICROSCOPY (2.59 Å) Cite: Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 2024

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