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2Z9A
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BU of 2z9a by Molmil
Crystal Structure of Human Saposin C Dimer in Open Conformation
Descriptor: GLYCEROL, Proactivator polypeptide
Authors:Rossmann, M, Saenger, W, Maier, T.
Deposit date:2007-09-18
Release date:2008-04-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2R0R
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BU of 2r0r by Molmil
Crystal Structure of Human Saposin D variant SapD K9E
Descriptor: Proactivator polypeptide, SULFATE ION
Authors:Rossmann, M, Saenger, W, Maier, T.
Deposit date:2007-08-21
Release date:2008-04-29
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
2R1Q
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BU of 2r1q by Molmil
Crystal Structure of Iodinated Human Saposin D in Space Group C2221
Descriptor: Proactivator polypeptide
Authors:Maier, T, Rossman, M, Saenger, W.
Deposit date:2007-08-23
Release date:2008-04-29
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions.
Structure, 16, 2008
9AXG
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BU of 9axg by Molmil
Human saposin B in the presence of globotriaosylceramide-NBD
Descriptor: MALONATE ION, Saposin-B
Authors:Sawyer, T.K, Garman, S.C.
Deposit date:2024-03-06
Release date:2024-03-13
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Human Saposin B Ligand Binding and Presentation to alpha-Galactosidase A.
Biorxiv, 2024
8EQU
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BU of 8equ by Molmil
Structure of SARS-CoV-2 Orf3a in late endosome/lysosome-like environment, Saposin A nanodisc
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ORF3a protein, Saposin A, ...
Authors:Miller, A.N, Houlihan, P.R, Matamala, E, Cabezas-Bratesco, D, Lee, G.Y, Cristofori-Armstrong, B, Dilan, T.L, Sanchez-Martinez, S, Matthies, D, Yan, R, Yu, Z, Ren, D, Brauchi, S.E, Clapham, D.E.
Deposit date:2022-10-09
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Elife, 12, 2023
5W7F
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BU of 5w7f by Molmil
Murine acyloxyacyl hydrolase (AOAH), S262A mutant, with lipid A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, 3-HYDROXY-TETRADECANOIC ACID, ...
Authors:Gorelik, A, Illes, K, Nagar, B.
Deposit date:2017-06-19
Release date:2018-01-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7P4T
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BU of 7p4t by Molmil
Tetrameric structure of murine SapA
Descriptor: Saposin-A
Authors:Shamin, M, Deane, J.E.
Deposit date:2021-07-13
Release date:2022-05-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:A Tetrameric Assembly of Saposin A: Increasing Structural Diversity in Lipid Transfer Proteins.
Contact, 4, 2021
5NXB
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BU of 5nxb by Molmil
Mouse galactocerebrosidase in complex with saposin A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Graham, S.C, Hill, C.H, Deane, J.E.
Deposit date:2017-05-09
Release date:2017-05-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The mechanism of glycosphingolipid degradation revealed by a GALC-SapA complex structure.
Nat Commun, 9, 2018
1SN6
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BU of 1sn6 by Molmil
NMR solution structure of human Saposin C in SDS micelles
Descriptor: Proactivator polypeptide
Authors:Hawkins, C.A, de Alba, E, Tjandra, N.
Deposit date:2004-03-10
Release date:2005-03-01
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of human saposin C in a detergent environment.
J.Mol.Biol., 346, 2005
1NKL
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BU of 1nkl by Molmil
NK-LYSIN FROM PIG, NMR, 20 STRUCTURES
Descriptor: NK-LYSIN
Authors:Otting, G, Liepinsh, E.
Deposit date:1997-04-17
Release date:1997-06-16
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Saposin fold revealed by the NMR structure of NK-lysin.
Nat.Struct.Biol., 4, 1997
1OF9
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BU of 1of9 by Molmil
Solution structure of the pore forming toxin of entamoeba histolytica (Amoebapore A)
Descriptor: PORE-FORMING PEPTIDE AMEOBAPORE A
Authors:Hecht, O, Schleinkofer, K, Bruhn, H, Leippe, M, Van Nuland, N, Dingley, A.J, Grotzinger, J.
Deposit date:2003-04-09
Release date:2004-02-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the Pore-Forming Protein of Entamoeba Histolytica
J.Biol.Chem., 279, 2004
2JSA
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BU of 2jsa by Molmil
Solution structure of Caenopore-5 (81 Pro Trans confomer)
Descriptor: Saposin-like protein family protein 5
Authors:Mysliwy, J, Grotzinger, J.
Deposit date:2007-07-02
Release date:2008-10-14
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Caenopore-5: the three-dimensional structure of an antimicrobial protein from Caenorhabditis elegans.
Dev.Comp.Immunol., 34, 2010
2JS9
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BU of 2js9 by Molmil
Structure of caenopore-5 (81 Pro cis conformer)
Descriptor: Saposin-like protein family protein 5
Authors:Mysliwy, J, Grotzinger, J.
Deposit date:2007-07-02
Release date:2008-10-14
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Caenopore-5: the three-dimensional structure of an antimicrobial protein from Caenorhabditis elegans.
Dev.Comp.Immunol., 34, 2010
1M12
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BU of 1m12 by Molmil
NMR solution structure of human Saposin C
Descriptor: SAPOSIN C
Authors:de Alba, E, Weiler, S, Tjandra, N.
Deposit date:2002-06-17
Release date:2003-07-29
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of human saposin C: pH-dependent interaction with phospholipid vesicles.
Biochemistry, 42, 2003
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