PDB: 62 resultsInfo pagesStatus searchChemie searchBIRD

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4XIL	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with MPD as the cryoprotectant Descriptor: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, Sialidase B Authors: Brear, P. Deposit date: 2015-01-07 Release date: 2016-01-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: `The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XHB	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with pentanediol and CHES Descriptor: (1R,2S)-cyclopentane-1,2-diol, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Sialidase B Authors: Brear, P. Deposit date: 2015-01-05 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.88 Å) Cite: The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XOG	CRYSTAL STRUCTURE OF THE NANB SIALIDASE FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH Optactin and DANA Descriptor: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, DIMETHYL SULFOXIDE, ... Authors: Brear, P. Deposit date: 2015-01-16 Release date: 2016-02-03 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.09 Å) Cite: The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XMA	Crystal structure of the K499G mutant of NanB sialidase from streptococcus pneumoniae in complex with Optactin Descriptor: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2015-01-14 Release date: 2016-02-03 Last modified: 2017-08-30 Method: X-RAY DIFFRACTION (2.09 Å) Cite: `The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
4XYX	NanB plus Optactamide Descriptor: Optactamide, PHOSPHATE ION, Sialidase B Authors: Rogers, G.W, Brear, P, Yang, L, Taylor, G.L, Westwood, N.J. Deposit date: 2015-02-03 Release date: 2016-02-10 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To Be Published
4YW4	Streptococcus pneumoniae sialidase NanC Descriptor: GLYCEROL, Neuraminidase C, PHOSPHATE ION Authors: Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L. Deposit date: 2015-03-20 Release date: 2016-04-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of a novel sialidase To be published
4YZ3	Crystal Structure of Streptococcus pneumoniae NanC, in complex with Oseltamivir. Descriptor: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase, SULFATE ION Authors: Lukacik, P, Owen, C.D, Potter, J.A, Taylor, G.L, Walsh, M.A. Deposit date: 2015-03-24 Release date: 2016-04-20 Last modified: 2017-09-13 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Crystal Structure of Streptococcus pneumoniae NanC. To Be Published
5FRA	CBM40_CPF0721-6'SL Descriptor: ACETATE ION, N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, ... Authors: Ribeiro, J.P, Pau, W, Pifferi, C, Renaudet, O, Varrot, A, Mahal, L.K, Imberty, A. Deposit date: 2015-12-16 Release date: 2016-07-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2 Å) Cite: Characterization of a High-Affinity Sialic Acid-Specific Cbm40 from Clostridium Perfringens and Engineering of a Divalent Form. Biochem.J., 473, 2016
5FRE	Characterization of a novel CBM from Clostridium perfringens Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, CALCIUM ION, ... Authors: Ribeiro, J, Pau, W, Pifferi, C, Renaudet, O, Varrot, A, Mahal, L.K, Imberty, A. Deposit date: 2015-12-17 Release date: 2016-07-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Characterization of a High-Affinity Sialic Acid-Specific Cbm40 from Clostridium Perfringens and Engineering of a Divalent Form. Biochem.J., 473, 2016
6ER3	Ruminococcus gnavus IT-sialidase CBM40 bound to alpha2,3 sialyllactose Descriptor: BNR/Asp-box repeat protein, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose Authors: Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. Deposit date: 2017-10-16 Release date: 2018-05-02 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus. Nat Commun, 8, 2017
6ER4	Ruminococcus gnavus IT-sialidase CBM40 bound to alpha2,6 sialyllactose Descriptor: BNR/Asp-box repeat protein, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... Authors: Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. Deposit date: 2017-10-16 Release date: 2018-05-02 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus. Nat Commun, 8, 2017
6ER2	Ruminococcus gnavus IT-sialidase CBM40 Descriptor: BNR/Asp-box repeat protein Authors: Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. Deposit date: 2017-10-16 Release date: 2018-05-02 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus. Nat Commun, 8, 2017

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