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8B8T
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Open conformation of the complex of DNA ligase I on PCNA and DNA in the presence of ATP
Descriptor: DNA ligase 1, Proliferating cell nuclear antigen
Authors:Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A.
Deposit date:2022-10-05
Release date:2023-01-11
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
7BUP
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BU of 7bup by Molmil
Crystal structure of PCNA from pathogenic yeast Candida albicans
Descriptor: Proliferating cell nuclear antigen
Authors:sundaram, R, Vasudevan, D.
Deposit date:2020-04-07
Release date:2021-02-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analyses of PCNA from the fungal pathogen Candida albicans identify three regions with species-specific conformations.
Febs Lett., 595, 2021
5DA7
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BU of 5da7 by Molmil
monomeric PCNA bound to a small protein inhibitor
Descriptor: DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ...
Authors:Ladner, J.E, Altieri, A.S, Kelman, Z.
Deposit date:2015-08-19
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res., 44, 2016
6O09
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BU of 6o09 by Molmil
Structure of AtPCNA in complex with the PIP motif of ATXR6
Descriptor: Proliferating cellular nuclear antigen 1, Uncharacterized protein
Authors:Couture, J.F, Davarinejad, H.
Deposit date:2019-02-15
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:ATXR5/6 Forms Alternative Protein Complexes with PCNA and the Nucleosome Core Particle.
J. Mol. Biol., 431, 2019
4HK1
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BU of 4hk1 by Molmil
Crystal Structure of PCNA from Drosophila melanogaster
Descriptor: Proliferating cell nuclear antigen
Authors:Wang, K, Shi, Z.B, Zhou, Z.C.
Deposit date:2012-10-14
Release date:2013-04-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structure of PCNA from Drosophila melanogaster.
Acta Crystallogr.,Sect.F, 69, 2013
1AXC
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BU of 1axc by Molmil
HUMAN PCNA
Descriptor: P21/WAF1, PCNA
Authors:Gulbis, J.M, Kuriyan, J.
Deposit date:1997-10-14
Release date:1998-01-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA.
Cell(Cambridge,Mass.), 87, 1996
7WP3
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BU of 7wp3 by Molmil
Crystal structure of the complex of proliferating cell nuclear antigen (PCNA) from Leishmania donovani with 1,5-Bis (4-amidinophenoxy) pentane (PNT) at 2.95 A resolution
Descriptor: 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, Proliferating cell nuclear antigen
Authors:Ahmad, M.I, Yadav, S.P, Singh, P.K, Sharma, P, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2022-01-22
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.954 Å)
Cite:Crystal structure of the complex of proliferating cell nuclear antigen (PCNA) from Leishmania donovani with 1,5-Bis (4-amidinophenoxy) pentane (PNT) at 2.95 A resolution
To Be Published
4YHR
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BU of 4yhr by Molmil
Crystal Structure of Yeast Proliferating Cell Nuclear Antigen
Descriptor: Proliferating cell nuclear antigen
Authors:Litman, J.M, Nguyen, V.Q, Kondratick, C.M, Powers, K.T, Schnieders, M.J, Washington, M.T.
Deposit date:2015-02-27
Release date:2015-03-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9502 Å)
Cite:Dead-End Elimination with a Polarizable Force Field Repacks PCNA Models from Low-Resolution X-ray Diffraction into Atomic Resolution Structures
To be published
4RJF
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BU of 4rjf by Molmil
Crystal structure of the human sliding clamp at 2.0 angstrom resolution
Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen
Authors:Kroker, A.J, Bruning, J.B.
Deposit date:2014-10-09
Release date:2015-08-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.0072 Å)
Cite:p21 Exploits Residue Tyr151 as a Tether for High-Affinity PCNA Binding.
Biochemistry, 54, 2015
1GE8
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BU of 1ge8 by Molmil
PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) HOMOLOG FROM PYROCOCCUS FURIOSUS
Descriptor: PROLIFERATION CELL NUCLEAR ANTIGEN
Authors:Matsumiya, S, Ishino, Y, Morikawa, K.
Deposit date:2000-10-18
Release date:2001-01-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of an archaeal DNA sliding clamp: proliferating cell nuclear antigen from Pyrococcus furiosus.
Protein Sci., 10, 2001
6D0Q
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BU of 6d0q by Molmil
Structure of a DNA retention-prone PCNA variant
Descriptor: Proliferating cell nuclear antigen
Authors:Kelch, B.A, Gaubitz, C.
Deposit date:2018-04-10
Release date:2019-05-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.80051017 Å)
Cite:Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex.
Nucleic Acids Res., 47, 2019
6D0R
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BU of 6d0r by Molmil
Structure of a DNA retention-prone PCNA variant
Descriptor: Proliferating cell nuclear antigen
Authors:Kelch, B.A, Gaubitz, C.
Deposit date:2018-04-10
Release date:2019-05-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.85856962 Å)
Cite:Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex.
Nucleic Acids Res., 47, 2019
3L0W
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BU of 3l0w by Molmil
Structure of split monoubiquitinated PCNA with ubiquitin in position two
Descriptor: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen
Authors:Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
Deposit date:2009-12-10
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
7QNZ
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BU of 7qnz by Molmil
human Lig1-DNA-PCNA complex reconstituted in absence of ATP
Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase 1, Oligo13P, ...
Authors:Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A.
Deposit date:2021-12-23
Release date:2023-01-11
Method:ELECTRON MICROSCOPY (4.58 Å)
Cite:Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
7QO1
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BU of 7qo1 by Molmil
complex of DNA ligase I and FEN1 on PCNA and DNA
Descriptor: ADENOSINE MONOPHOSPHATE, DNA ligase 1, Flap endonuclease 1, ...
Authors:Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A.
Deposit date:2021-12-23
Release date:2023-01-11
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
3L10
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BU of 3l10 by Molmil
Structure of split monoubiquitinated PCNA with ubiquitin in position one
Descriptor: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen
Authors:Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
Deposit date:2009-12-10
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
4L6P
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BU of 4l6p by Molmil
Structure of C22Y Mutant PCNA protein defective in DNA mismatch repair
Descriptor: GLYCEROL, Proliferating cell nuclear antigen
Authors:Washington, T, Boehm, E.
Deposit date:2013-06-12
Release date:2014-10-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Distinct structural alterations in proliferating cell nuclear antigen block DNA mismatch repair.
Biochemistry, 52, 2013
8E84
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BU of 8e84 by Molmil
Human PCNA mutant- C148S
Descriptor: Proliferating cell nuclear antigen
Authors:Magrino, J, Page, B, Gaubitz, C, Kelch, B.A.
Deposit date:2022-08-25
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder.
J.Biol.Chem., 299, 2023
4L60
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BU of 4l60 by Molmil
Structure of C81R Mutant PCNA Protein Defective in Mismatch Repair
Descriptor: Proliferating cell nuclear antigen
Authors:Washington, T, Boehm, E.
Deposit date:2013-06-11
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Distinct structural alterations in proliferating cell nuclear antigen block DNA mismatch repair.
Biochemistry, 52, 2013
7EP8
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BU of 7ep8 by Molmil
Crystal structure of PCNA from Neurospora crassa
Descriptor: Proliferating cell nuclear antigen
Authors:Sundaram, R, Vasudevan, D.
Deposit date:2021-04-26
Release date:2021-06-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Interdomain connecting loop and J loop structures determine cross-species compatibility of PCNA.
J.Biol.Chem., 297, 2021
2NTI
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BU of 2nti by Molmil
Crystal structure of PCNA123 heterotrimer.
Descriptor: 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, BROMIDE ION, DNA polymerase sliding clamp A, ...
Authors:Hlinkova, V, Ling, H.
Deposit date:2006-11-07
Release date:2007-12-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
4CS5
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BU of 4cs5 by Molmil
Crystal Structure of PCNA from Litopenaeus vannamei
Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:Carrasco-Miranda, J.S, Lopez-Zavala, A.A, De-La-Mora, E, Rudino-Pinera, E, Brieba, L.G, Sotelo-Mundo, R.R.
Deposit date:2014-03-04
Release date:2014-04-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of the Shrimp Proliferating Cell Nuclear Antigen: Structural Complementarity with Wssv DNA Polymerase Pip-Box.
Plos One, 9, 2014
7EFA
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BU of 7efa by Molmil
Crystal structure of the complex between the C-terminal domain of mouse MUTYH and human PCNA
Descriptor: Adenine DNA glycosylase, Proliferating cell nuclear antigen
Authors:Nakamura, T, Nakabeppu, Y, Yamagata, Y.
Deposit date:2021-03-21
Release date:2021-06-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer.
Nucleic Acids Res., 49, 2021
5YD8
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BU of 5yd8 by Molmil
Crystal structure of human PCNA in complex with APIM of human ZRANB3
Descriptor: Proliferating cell nuclear antigen, ZRANB3
Authors:Hashimoto, H, Tagata, R.
Deposit date:2017-09-12
Release date:2018-04-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of proliferating cell nuclear antigen (PCNA) bound to an APIM peptide reveals the universality of PCNA interaction.
Acta Crystallogr.,Sect.F, 74, 2018
4D2G
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BU of 4d2g by Molmil
Crystal structure of human PCNA in complex with p15 peptide
Descriptor: P15, PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:DeBiasio, A, Ibanez, A, Mortuza, G, Molina, R, Cordeiro, T.N, Castillo, F, Villate, M, Merino, N, Lelli, M, Diercks, T, Luque, I, Bernardo, P, Montoya, G, Blanco, F.J.
Deposit date:2014-05-09
Release date:2015-03-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
Nat.Commun., 6, 2015

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