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1RER
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BU of 1rer by Molmil
Crystal structure of the homotrimer of fusion glycoprotein E1 from Semliki Forest Virus.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gibbons, D.L, Vaney, M.C, Roussel, A, Vigouroux, A, Reilly, B, Kielian, M, Rey, F.A.
Deposit date:2003-11-07
Release date:2004-01-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Conformational change and protein-protein interactions of the fusion protein of Semliki Forest virus.
Nature, 427, 2004
2ALA
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BU of 2ala by Molmil
Crystal structure of the Semliki Forest Virus envelope protein E1 in its monomeric conformation.
Descriptor: Structural polyprotein (P130)
Authors:Roussel, A, Lescar, J, Vaney, M.C, Wengler, G, Wengler, G, Rey, F.A.
Deposit date:2005-08-05
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and interactions at the viral surface of the envelope protein E1 of Semliki Forest virus.
Structure, 14, 2006
1I9W
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BU of 1i9w by Molmil
CRYSTAL STRUCTURE OF THE FUSION GLYCOPROTEIN E1 FROM SEMLIKI FOREST VIRUS
Descriptor: FUSION PROTEIN E1
Authors:Lescar, J, Roussel, A, Wien, M.W, Navaza, J, Fuller, S.D, Wengler, G, Wengler, G, Rey, F.A.
Deposit date:2001-03-21
Release date:2002-04-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pH.
Cell(Cambridge,Mass.), 105, 2001
8DEQ
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BU of 8deq by Molmil
Cryo-EM local refinement of antibody SKV09 in complex with VEEV alphavirus spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SKV09 Fab Heavy Chain, SKV09 Fab Light Chain, ...
Authors:Casner, R.G, Verardi, R, Roederer, M, Shapiro, L.
Deposit date:2022-06-21
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8D87
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BU of 8d87 by Molmil
Fitted crystal structure of the homotrimer of fusion glycoprotein E1 from SFV into subtomogram averaged CHIKV E1 glycoprotein density
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Mangala Prasad, V, Lee, K.K.
Deposit date:2022-06-08
Release date:2022-08-31
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (27.200001 Å)
Cite:Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery.
Nat Commun, 13, 2022
2YEW
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BU of 2yew by Molmil
Modeling Barmah Forest virus structural proteins
Descriptor: CAPSID PROTEIN, E1 ENVELOPE GLYCOPROTEIN, E2 ENVELOPE GLYCOPROTEIN
Authors:Kostyuchenko, V.A, Jakana, J, Liu, X, Haddow, A.D, Aung, M, Weaver, S.C, Chiu, W, Lok, S.M.
Deposit date:2011-03-31
Release date:2012-04-18
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (5 Å)
Cite:The Structure of Barmah Forest Virus as Revealed by Cryo-Electron Microscopy at a 6-Angstrom Resolution Has Detailed Transmembrane Protein Architecture and Interactions.
J.Virol., 85, 2011
7LIH
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BU of 7lih by Molmil
CryoEM structure of Mayaro virus icosahedral subunit
Descriptor: Capsid protein, E1 protein, E2 protein
Authors:Chmielewski, D, Kaelber, J.T, Jin, J, Weaver, S, Auguste, A.J, Chiu, W.
Deposit date:2021-01-27
Release date:2022-02-09
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Near-atomic resolution Cryo-EM structure of Mayaro virus identifies key structural determinants of alphavirus particle formation
To Be Published
8IHP
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BU of 8ihp by Molmil
Structure of Semliki Forest virus VLP in complex with the receptor VLDLR-LA3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
Authors:Cao, D, Ma, B, Cao, Z, Zhang, X, Xiang, Y.
Deposit date:2023-02-23
Release date:2023-04-12
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of Semliki Forest virus in complex with its receptor VLDLR.
Cell, 186, 2023
8SQN
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BU of 8sqn by Molmil
CryoEM structure of Western equine encephalitis virus VLP in complex with the chimeric Du-D1-Mo-D2 MXRA8 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DuD1MoD2 chimeric MXRA8, E1 envelope glycoprotein, ...
Authors:Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2023-05-04
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8.
Cell, 186, 2023
5ANY
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BU of 5any by Molmil
Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab CHK265
Descriptor: E1, E2, FAB, ...
Authors:Fox, J.M, Long, F, Edeling, M.A, Lin, H, Duijl-Richter, M, Fong, R.H, Kahle, K.M, Smit, J.M, Jin, J, Simmons, G, Doranz, B.J, Crowe, J.E, Fremont, D.H, Rossmann, M.G, Diamond, M.S.
Deposit date:2015-09-08
Release date:2015-11-25
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (16.9 Å)
Cite:Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.
Cell(Cambridge,Mass.), 163, 2015
5VU2
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BU of 5vu2 by Molmil
Electron cryo-microscopy of "immature" Chikungunya VLP
Descriptor: E1 envelope glycoprotein, E2 envelope glycoprotein, E3 envelope glycoprotein, ...
Authors:Rossmann, M.G, Yap, M.L.
Deposit date:2017-05-18
Release date:2017-12-06
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Structural studies of Chikungunya virus maturation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1Z8Y
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BU of 1z8y by Molmil
Mapping the E2 Glycoprotein of Alphaviruses
Descriptor: Capsid protein C, Spike glycoprotein E1, Spike glycoprotein E2
Authors:Mukhopadhyay, S, Zhang, W, Gabler, S, Chipman, P.R, Strauss, E.G, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G.
Deposit date:2005-03-31
Release date:2006-02-07
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Mapping the structure and function of the E1 and E2 glycoproteins in alphaviruses.
Structure, 14, 2006
7KO8
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BU of 7ko8 by Molmil
Cryo-EM structure of the mature and infective Mayaro virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
Authors:Riberio-Filho, H.V, Coimbra, L.D, Cassago, A, Rocha, R.P.F, Padilha, A.C.M, Schatz, M, van Heel, M.G, Portugal, R.V, Trivella, D.B.B, de Oliveira, P.S.L, Marques, R.E.
Deposit date:2020-11-06
Release date:2021-04-28
Last modified:2021-11-10
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM structure of the mature and infective Mayaro virus at 4.4 angstrom resolution reveals features of arthritogenic alphaviruses.
Nat Commun, 12, 2021
6IMM
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BU of 6imm by Molmil
Cryo-EM structure of an alphavirus, Sindbis virus
Descriptor: Assembly protein E3, Octadecane, Spike glycoprotein E1, ...
Authors:Zhang, X, Ma, J, Chen, L.
Deposit date:2018-10-23
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Implication for alphavirus host-cell entry and assembly indicated by a 3.5 angstrom resolution cryo-EM structure.
Nat Commun, 9, 2018
6XO4
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BU of 6xo4 by Molmil
CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP
Descriptor: Togavirin
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2020-07-06
Release date:2020-12-23
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.
Cell, 183, 2020
6XOB
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BU of 6xob by Molmil
CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP with Fab EEEV-143.
Descriptor: EEEV-143 Fab heavy chain, EEEV-143 Fab light chain, Togavirin
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2020-07-06
Release date:2020-12-23
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.
Cell, 183, 2020
6JO8
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BU of 6jo8 by Molmil
The complex structure of CHIKV envelope glycoprotein bound to human MXRA8
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHIKV E1, ...
Authors:Song, H, Zhao, Z, Qi, J, Gao, F, Gao, F.G.
Deposit date:2019-03-20
Release date:2019-05-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.495 Å)
Cite:Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein.
Cell, 177, 2019
2XFB
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BU of 2xfb by Molmil
CHIKUNGUNYA E1 E2 ENVELOPE GLYCOPROTEINS FITTED IN SINDBIS VIRUS cryo- EM MAP
Descriptor: E1 ENVELOPE GLYCOPROTEIN, E2 ENVELOPE GLYCOPROTEIN
Authors:Voss, J.E, Vaney, M.C, Duquerroy, S, Rey, F.A.
Deposit date:2010-05-21
Release date:2010-11-24
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Glycoprotein Organization of Chikungunya Virus Particles Revealed by X-Ray Crystallography
Nature, 468, 2010
2XFC
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BU of 2xfc by Molmil
CHIKUNGUNYA E1 E2 ENVELOPE GLYCOPROTEINS FITTED IN SEMLIKI FOREST VIRUS cryo-EM MAP
Descriptor: E1 ENVELOPE GLYCOPROTEIN, E2 ENVELOPE GLYCOPROTEIN
Authors:Voss, J.E, Vaney, M.C, Duquerroy, S, Rey, F.A.
Deposit date:2010-05-21
Release date:2010-11-24
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Glycoprotein Organization of Chikungunya Virus Particles Revealed by X-Ray Crystallography
Nature, 468, 2010
1LD4
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BU of 1ld4 by Molmil
Placement of the Structural Proteins in Sindbis Virus
Descriptor: Coat protein C, GENERAL CONTROL PROTEIN GCN4, Spike glycoprotein E1, ...
Authors:Zhang, W, Mukhopadhyay, S, Pletnev, S.V, Baker, T.S, Kuhn, R.J, Rossmann, M.G.
Deposit date:2002-04-08
Release date:2002-11-04
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (11.4 Å)
Cite:Placement of the Structural Proteins in Sindbis virus
J.VIROL., 76, 2002
8UFB
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BU of 8ufb by Molmil
Eastern equine encephalitis virus (PE-6) VLP in complex with full-length VLDLR (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2023-10-04
Release date:2024-01-17
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.
Cell, 187, 2024
8UFC
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BU of 8ufc by Molmil
Eastern equine encephalitis virus (PE-6) VLP in complex with VLDLR LA(1-2) (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2023-10-04
Release date:2024-01-17
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.
Cell, 187, 2024
8UFA
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BU of 8ufa by Molmil
Eastern equine encephalitis virus (PE-6) VLP (asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 protein, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2023-10-04
Release date:2024-01-17
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.
Cell, 187, 2024
7SFW
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BU of 7sfw by Molmil
CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP in complex with Fab hVEEV-63 (focus refine of the asymmetric unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, Spike glycoprotein E1, ...
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2021-10-04
Release date:2022-03-16
Last modified:2022-07-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge.
J.Exp.Med., 219, 2022
7SFU
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BU of 7sfu by Molmil
CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, Spike glycoprotein E1, ...
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2021-10-04
Release date:2022-03-16
Last modified:2022-07-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge.
J.Exp.Med., 219, 2022

 

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數據於2024-05-01公開中

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