7DHF
 
 | | Vibrio vulnificus Wzb in complex with benzylphosphonate | | Descriptor: | GLYCEROL, PHOSPHATE ION, Protein-tyrosine-phosphatase | | Authors: | Ma, Q, Wang, X. | | Deposit date: | 2020-11-14 | | Release date: | 2021-01-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.211 Å) | | Cite: | Wzb of Vibrio vulnificus represents a new group of low-molecular-weight protein tyrosine phosphatases with a unique insertion in the W-loop.
J.Biol.Chem., 296, 2021
|
|
7DHE
 | | Vibrio vulnificus Wzb in complex with benzylphosphonate | | Descriptor: | Protein-tyrosine-phosphatase, benzylphosphonic acid | | Authors: | Ma, Q, Wang, X. | | Deposit date: | 2020-11-14 | | Release date: | 2021-01-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Wzb of Vibrio vulnificus represents a new group of low-molecular-weight protein tyrosine phosphatases with a unique insertion in the W-loop.
J.Biol.Chem., 296, 2021
|
|
3JVI
 | |
1RXI
 | | pI258 arsenate reductase (ArsC) triple mutant C10S/C15A/C82S | | Descriptor: | Arsenate reductase, CHLORIDE ION, PERCHLORATE ION, ... | | Authors: | Messens, J, Van Molle, I, Vanhaesebrouck, P, Limbourg, M, Van Belle, K, Wahni, K, Martins, J.C, Loris, R, Wyns, L. | | Deposit date: | 2003-12-18 | | Release date: | 2004-06-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct.
Acta Crystallogr.,Sect.D, 60, 2004
|
|
1D1Q
 | | CRYSTAL STRUCTURE OF A YEAST LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LTP1) COMPLEXED WITH THE SUBSTRATE PNPP | | Descriptor: | 4-NITROPHENYL PHOSPHATE, GLYCEROL, PHOSPHATE ION, ... | | Authors: | Wang, S, Tabernero, L, Zhang, M, Harms, E, Van Etten, R.L, Staufacher, C.V. | | Deposit date: | 1999-09-20 | | Release date: | 2000-03-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structures of a low-molecular weight protein tyrosine phosphatase from Saccharomyces cerevisiae and its complex with the substrate p-nitrophenyl phosphate.
Biochemistry, 39, 2000
|
|
1D2A
 | | CRYSTAL STRUCTURE OF A YEAST LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LTP1) COMPLEXED WITH THE ACTIVATOR ADENINE | | Descriptor: | ADENINE, CHLORIDE ION, PHOSPHATE ION, ... | | Authors: | Wang, S, Stauffacher, C.V, Van Etten, R.L. | | Deposit date: | 1999-09-22 | | Release date: | 2000-03-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural and mechanistic basis for the activation of a low-molecular weight protein tyrosine phosphatase by adenine.
Biochemistry, 39, 2000
|
|
1U2Q
 | | Crystal structure of Mycobacterium tuberculosis Low Molecular Weight Protein Tyrosine Phosphatase (MPtpA) at 2.5A resolution with glycerol in the active site | | Descriptor: | CHLORIDE ION, GLYCEROL, low molecular weight protein-tyrosine-phosphatase | | Authors: | Madhurantakam, C, Rajakumara, E, Mazumdar, P.A, Saha, B, Mitra, D, Wiker, H.G, Sankaranarayanan, R, Das, A.K. | | Deposit date: | 2004-07-20 | | Release date: | 2005-03-22 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of Low-Molecular-Weight Protein Tyrosine Phosphatase from Mycobacterium tuberculosis at 1.9-A Resolution
J.Bacteriol., 187, 2005
|
|
1U2P
 | | Crystal structure of Mycobacterium tuberculosis Low Molecular Protein Tyrosine Phosphatase (MPtpA) at 1.9A resolution | | Descriptor: | CHLORIDE ION, low molecular weight protein-tyrosine-phosphatase | | Authors: | Madhurantakam, C, Rajakumara, E, Mazumdar, P.A, Saha, B, Mitra, D, Wiker, H.G, Sankaranarayanan, R, Das, A.K. | | Deposit date: | 2004-07-20 | | Release date: | 2005-03-22 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of Low-Molecular-Weight Protein Tyrosine Phosphatase from Mycobacterium tuberculosis at 1.9-A Resolution
J.Bacteriol., 187, 2005
|
|
3JS5
 | |
7CUY
 | | Crystal structure of Primo-1 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Low molecular weight phosphotyrosine protein phosphatase 1 | | Authors: | Lee, H.S, Kim, S.J, Ku, B. | | Deposit date: | 2020-08-25 | | Release date: | 2021-01-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.081 Å) | | Cite: | Structural and Biochemical Characterization of the Two Drosophila Low Molecular Weight-Protein Tyrosine Phosphatases DARP and Primo-1.
Mol.Cells, 43, 2020
|
|
1JFV
 | | X-Ray Structure of oxidised C10S, C15A arsenate reductase from pI258 | | Descriptor: | PERCHLORATE ION, POTASSIUM ION, arsenate reductase | | Authors: | Zegers, I, Martins, J.C, Willem, R, Wyns, L, Messens, J. | | Deposit date: | 2001-06-22 | | Release date: | 2001-10-03 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Arsenate reductase from S. aureus plasmid pI258 is a phosphatase drafted for redox duty.
Nat.Struct.Biol., 8, 2001
|
|
1JF8
 | | X-ray structure of reduced C10S, C15A arsenate reductase from pI258 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BICARBONATE ION, POTASSIUM ION, ... | | Authors: | Zegers, I, Martins, J.C, Willem, R, Wyns, L, Messens, J. | | Deposit date: | 2001-06-20 | | Release date: | 2001-10-03 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.12 Å) | | Cite: | Arsenate reductase from S. aureus plasmid pI258 is a phosphatase drafted for redox duty.
Nat.Struct.Biol., 8, 2001
|
|
1JL3
 | | Crystal Structure of B. subtilis ArsC | | Descriptor: | ARSENATE REDUCTASE, SULFATE ION | | Authors: | Su, X.-D, Bennett, M.S. | | Deposit date: | 2001-07-15 | | Release date: | 2001-10-24 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Bacillus subtilis arsenate reductase is structurally and functionally similar to low molecular weight protein tyrosine phosphatases.
Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
1LK0
 | | Disulfide intermediate of C89L Arsenate reductase from pI258 | | Descriptor: | CHLORIDE ION, POTASSIUM ION, arsenate reductase | | Authors: | Messens, J, Martins, J.C, Van Belle, K, Brosens, E, Desmyter, A, De Gieter, M, Wieruszeski, J.M, Willem, R, Wyns, L, Zegers, I. | | Deposit date: | 2002-04-23 | | Release date: | 2002-08-07 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade.
Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
1LJL
 | | Wild Type pI258 S. aureus arsenate reductase | | Descriptor: | POTASSIUM ION, arsenate reductase | | Authors: | Messens, J, Martins, J.C, Van Belle, K, Brosens, E, Desmyter, A, De Gieter, M, Wieruszeski, J.M, Willem, R, Wyns, L, Zegers, I. | | Deposit date: | 2002-04-21 | | Release date: | 2002-08-07 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade.
Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
5JNW
 | | Crystal structure of bovine low molecular weight protein tyrosine phosphatase (LMPTP) mutant (W49Y N50E) complexed with vanadate and uncompetitive inhibitor | | Descriptor: | 2-(4-{[3-(piperidin-1-yl)propyl]amino}quinolin-2-yl)benzonitrile, Low molecular weight phosphotyrosine protein phosphatase, VANADATE ION | | Authors: | Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N. | | Deposit date: | 2016-04-30 | | Release date: | 2017-03-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
|
|
5JNV
 | | Crystal structure of bovine low molecular weight protein tyrosine phosphatase (LMPTP) mutant (W49Y N50E) complexed with HEPES | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, Low molecular weight phosphotyrosine protein phosphatase | | Authors: | Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N. | | Deposit date: | 2016-04-30 | | Release date: | 2017-03-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
|
|
5JNT
 | | Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A complexed with MES | | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... | | Authors: | Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N. | | Deposit date: | 2016-04-30 | | Release date: | 2017-03-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
|
|
5JNR
 | | Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A | | Descriptor: | Low molecular weight phosphotyrosine protein phosphatase | | Authors: | Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N. | | Deposit date: | 2016-04-30 | | Release date: | 2017-03-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
|
|
5JNU
 | | Crystal structure of mouse Low-Molecular Weight Protein Tyrosine Phosphatase type A (LMPTP-A) complexed with phosphate | | Descriptor: | Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION | | Authors: | Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N. | | Deposit date: | 2016-04-30 | | Release date: | 2017-03-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.535 Å) | | Cite: | Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
|
|
5JNS
 | | Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A complexed with phosphate | | Descriptor: | DIMETHYL SULFOXIDE, Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION | | Authors: | Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N. | | Deposit date: | 2016-04-30 | | Release date: | 2017-03-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
|
|
1Z2D
 | | Solution Structure of Bacillus subtilis ArsC in reduced state | | Descriptor: | Arsenate reductase | | Authors: | Jin, C, Li, Y. | | Deposit date: | 2005-03-08 | | Release date: | 2005-10-04 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution Structures and Backbone Dynamics of Arsenate Reductase from Bacillus subtilis: REVERSIBLE CONFORMATIONAL SWITCH ASSOCIATED WITH ARSENATE REDUCTION
J.Biol.Chem., 280, 2005
|
|
1ZGG
 | |
1Z12
 | | Crystal Structure of Bovine Low Molecular Weight PTPase Complexed with Vanadate | | Descriptor: | Low molecular weight phosphotyrosine protein phosphatase, VANADATE ION | | Authors: | Zhang, M, Zhou, M, Van Etten, R.L, Stauffacher, C.V. | | Deposit date: | 2005-03-03 | | Release date: | 2005-04-05 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of Bovine Low Molecular Weight Phosphotyrosyl Phosphatase Complexed with the Transition State Analog Vanadate
Biochemistry, 36, 1997
|
|
1Y1L
 | |
