8R5T
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4J5H
| Crystal Structure of B. thuringiensis AiiA mutant F107W with N-decanoyl-L-homoserine bound at the active site | Descriptor: | GLYCEROL, N-acyl homoserine lactonase, N-decanoyl-L-homoserine, ... | Authors: | Liu, C.F, Liu, D, Momb, J, Thomas, P.W, Lajoie, A, Petsko, G.A, Fast, W, Ringe, D. | Deposit date: | 2013-02-08 | Release date: | 2013-06-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-gamma-lactonase from Bacillus thuringiensis. Biochemistry, 52, 2013
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2UYX
| metallo-beta-lactamase (1BC2) single point mutant D120S | Descriptor: | BETA-LACTAMASE II, GLYCEROL, ZINC ION | Authors: | Larrull, L.I, Fabiane, S.M, Kowalski, J.M, Bennett, B, Sutton, B.J, Vila, A.J. | Deposit date: | 2007-04-20 | Release date: | 2007-05-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Asp-120 locates Zn2 for optimal metallo-beta-lactamase activity. J. Biol. Chem., 282, 2007
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8SKP
| X-ray structure of the NDM-4 beta-lactamase from Klebsiella pneumonia in complex with 1-hydroxypyridine-2(1H)-thione-6-carboxylic acid | Descriptor: | 1,2-ETHANEDIOL, 1-hydroxy-6-sulfanylidene-1,6-dihydropyridine-2-carboxylic acid, Metallo-beta-lactamase type 2, ... | Authors: | Thoden, J.B, Holden, H.M. | Deposit date: | 2023-04-20 | Release date: | 2023-08-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Characterization of a novel inhibitor for the New Delhi metallo-beta-lactamase-4: Implications for drug design and combating bacterial drug resistance. J.Biol.Chem., 299, 2023
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8SKO
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8SK2
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1JJE
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4YSB
| Crystal structure of ETHE1 from Myxococcus xanthus | Descriptor: | FE (III) ION, Metallo-beta-lactamase family protein | Authors: | Sattler, S.A, Wang, X, DeHan, P.J, Xun, L, Kang, C. | Deposit date: | 2015-03-17 | Release date: | 2015-06-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5015 Å) | Cite: | Characterizations of Two Bacterial Persulfide Dioxygenases of the Metallo-beta-lactamase Superfamily. J.Biol.Chem., 290, 2015
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4YSK
| Crystal structure of apo-form SdoA from Pseudomonas putida | Descriptor: | Beta-lactamase domain protein, FE (III) ION | Authors: | Sattler, S.A, Wang, X, DeHan, P.J, Xun, L, Kang, C. | Deposit date: | 2015-03-17 | Release date: | 2015-06-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.466 Å) | Cite: | Characterizations of Two Bacterial Persulfide Dioxygenases of the Metallo-beta-lactamase Superfamily. J.Biol.Chem., 290, 2015
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4YSL
| Crystal structure of SdoA from Pseudomonas putida in complex with glutathione | Descriptor: | Beta-lactamase domain protein, FE (III) ION, GLUTATHIONE | Authors: | Sattler, S.A, Wang, X, DeHan, P.J, Xun, L, Kang, C. | Deposit date: | 2015-03-17 | Release date: | 2015-06-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.4618 Å) | Cite: | Characterizations of Two Bacterial Persulfide Dioxygenases of the Metallo-beta-lactamase Superfamily. J.Biol.Chem., 290, 2015
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8D2Z
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1KO3
| VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa with Cys221 reduced | Descriptor: | ACETATE ION, CHLORIDE ION, HYDROXIDE ION, ... | Authors: | Garcia-Saez, I, Docquier, J.-D, Rossolini, G.M, Dideberg, O. | Deposit date: | 2001-12-20 | Release date: | 2003-09-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | The three-dimensional structure of VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form J.Mol.Biol., 375, 2008
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8U00
| Crystal structure of metallo-beta-lactamase superfamily protein from Caulobacter vibrioides | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Kim, Y, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) | Deposit date: | 2023-08-28 | Release date: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of metallo-beta-lactamase superfamily protein from Caulobacter vibrioides To Be Published
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1KO2
| VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa with an oxidized Cys (cysteinesulfonic) | Descriptor: | ACETATE ION, VIM-2 metallo-beta-lactamase, ZINC ION | Authors: | Garcia-Saez, I, Docquier, J.-D, Rossolini, G.M, Dideberg, O. | Deposit date: | 2001-12-20 | Release date: | 2003-09-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The three-dimensional structure of VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form J.Mol.Biol., 375, 2008
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2WHG
| Crystal Structure of the Di-Zinc Metallo-beta-lactamase VIM-4 from Pseudomonas aeruginosa | Descriptor: | CITRATE ANION, VIM-4 METALLO-BETA-LACTAMASE, ZINC ION | Authors: | Lassaux, P, Traore, D.A.K, Galleni, M, Ferrer, J.L. | Deposit date: | 2009-05-05 | Release date: | 2010-05-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Biochemical and Structural Characterization of the Subclass B1 Metallo-{Beta}-Lactamase Vim-4. Antimicrob.Agents Chemother., 55, 2011
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1K07
| Native FEZ-1 metallo-beta-lactamase from Legionella gormanii | Descriptor: | ACETATE ION, FEZ-1 beta-lactamase, GLYCEROL, ... | Authors: | Garcia-Saez, I, Mercuri, P.S, Kahn, R, Papamicael, C, Frere, J.M, Galleni, M, Dideberg, O. | Deposit date: | 2001-09-18 | Release date: | 2003-01-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Three-dimensional Structure of FEZ-1, a Monomeric Subclass B3 Metallo-[beta]-lactamase from Fluoribacter gormanii, in Native Form and in Complex with -Captopril J.MOL.BIOL., 325, 2003
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2WRS
| Crystal Structure of the Mono-Zinc Metallo-beta-lactamase VIM-4 from Pseudomonas aeruginosa | Descriptor: | BETA-LACTAMASE VIM-4, CITRATE ANION, CITRIC ACID, ... | Authors: | Lassaux, P, Hamel, M, Gulea, M, Delbruck, H, Traore, D.A.K, Mercuri, P.S, Horsfall, L, Dehareng, D, Gaumont, A.-C, Frere, J.-M, Ferrer, J.-L, Hoffmann, K, Galleni, M, Bebrone, C. | Deposit date: | 2009-09-02 | Release date: | 2010-06-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-Beta-Lactamases. J.Med.Chem., 53, 2010
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2VW8
| Crystal Structure of Quinolone signal response protein pqsE from Pseudomonas aeruginosa | Descriptor: | 1,2-ETHANEDIOL, CACODYLATE ION, FE (II) ION, ... | Authors: | Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, Oke, M, Naismith, J.H, White, M.F. | Deposit date: | 2008-06-17 | Release date: | 2010-07-14 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs. J.Struct.Funct.Genomics, 11, 2010
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4KEP
| Crystal structure of 4-pyridoxolactonase, wild-type | Descriptor: | 1,2-ETHANEDIOL, 4-pyridoxolactonase, ACETATE ION, ... | Authors: | Kobayashi, J, Yoshikane, Y, Baba, S, Mizutani, K, Takahashi, N, Mikami, B, Yagi, T. | Deposit date: | 2013-04-26 | Release date: | 2014-04-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structure of 4-pyridoxolactonase from Mesorhizobium loti. Acta Crystallogr.,Sect.F, 70, 2014
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4KEQ
| Crystal structure of 4-pyridoxolactonase, 5-pyridoxolactone bound | Descriptor: | 1,2-ETHANEDIOL, 4-pyridoxolactonase, 7-hydroxy-6-methylfuro[3,4-c]pyridin-3(1H)-one, ... | Authors: | Kobayashi, J, Yoshikane, Y, Baba, S, Mizutani, K, Takahashi, N, Mikami, B, Yagi, T. | Deposit date: | 2013-04-26 | Release date: | 2014-04-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.279 Å) | Cite: | Structure of 4-pyridoxolactonase from Mesorhizobium loti. Acta Crystallogr.,Sect.F, 70, 2014
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4NQ5
| Bacillus cereus Zn-dependent metallo-beta-lactamase at pH 7 complexed with compound CS319 | Descriptor: | (3R,5R,7aS)-5-(sulfanylmethyl)tetrahydro[1,3]thiazolo[4,3-b][1,3]thiazole-3-carboxylic acid, Beta-lactamase 2, POTASSIUM ION, ... | Authors: | Gonzalez, J.M, Gonzalez, M.M, Vila, A.J. | Deposit date: | 2013-11-23 | Release date: | 2014-11-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Inhibition of metallo-lactamases with bicyclic compounds TO BE PUBLISHED
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4NQ2
| Structure of Zn(II)-bound metallo-beta-lactamse VIM-2 from Pseudomonas aeruginosa | Descriptor: | ACETATE ION, Beta-lactamase class B VIM-2, ZINC ION | Authors: | Aitha, M, Nix, J.C, Crowder, M.W, Page, R.C. | Deposit date: | 2013-11-23 | Release date: | 2014-11-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Biochemical, Mechanistic, and Spectroscopic Characterization of Metallo-beta-lactamase VIM-2. Biochemistry, 53, 2014
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1JT1
| FEZ-1 metallo-beta-lactamase from Legionella gormanii modelled with D-captopril | Descriptor: | 1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC ACID, CHLORIDE ION, FEZ-1, ... | Authors: | Garcia-Saez, I, Mercuri, P.S, Kahn, R, Papamicael, C, Frere, J.M, Galleni, M, Dideberg, O. | Deposit date: | 2001-08-20 | Release date: | 2003-01-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Three-dimensional Structure of FEZ-1, a Monomeric Subclass B3 Metallo-[beta]-lactamase from Fluoribacter gormanii, in Native Form and in Complex with -Captopril J.MOL.BIOL., 325, 2003
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1L9Y
| FEZ-1-Y228A, A Mutant of the Metallo-beta-lactamase from Legionella gormanii | Descriptor: | CHLORIDE ION, FEZ-1 b-lactamase, GLYCEROL, ... | Authors: | Garcia-Saez, I, Mercuri, P.S, Galleni, M, Dideberg, O. | Deposit date: | 2002-03-27 | Release date: | 2003-07-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Three-dimensional Structure of FEZ-1, a Monomeric Subclass B3 Metallo-beta-lactamase
from Fluoribacter gormanii, in Native Form and in Complex with -Captopril J.Mol.Biol., 325, 2003
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6DD0
| Crystal structure of VIM-2 complexed with compound 8 | Descriptor: | ACETATE ION, Beta-lactamase class B VIM-2, ZINC ION, ... | Authors: | Pemberton, O.A, Chen, Y. | Deposit date: | 2018-05-08 | Release date: | 2019-05-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem., 62, 2019
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