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6H4E	Proteus mirabilis N-acetylneuraminate lyase Descriptor: Putative N-acetylneuraminate lyase, SULFATE ION Authors: North, R.A, Garcia-Bonete, M.J, Goyal, P, Katona, G, Dobson, R.C.J, Friemann, R. Deposit date: 2018-07-21 Release date: 2019-06-26 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.561 Å) Cite: The structure of Proteus mirabilis N-acetylneuraminate lyase reveals an intermolecular disulphide bond To Be Published
6H2R	Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/D181Q/A198L variant Descriptor: 1,2-ETHANEDIOL, 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase, GLYCEROL, ... Authors: Crennell, S.J, Danson, M.J, Royer, S. Deposit date: 2018-07-16 Release date: 2019-07-31 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.574 Å) Cite: Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/D181Q/A198L variant To Be Published
6H7R	Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/A198L variant Descriptor: 1,2-ETHANEDIOL, 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase, GLYCEROL Authors: Crennell, S.J, Danson, M.J, Royer, S. Deposit date: 2018-07-31 Release date: 2019-08-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/A198L variant To Be Published
1XL9	Crystal Structure of Dihydrodipicolinate Synthase DapA-2 (BA3935) from Bacillus Anthracis. Descriptor: dihydrodipicolinate synthase Authors: Blagova, E, Levdikov, V, Milioti, N, Fogg, M.J, Kalliomaa, A.K, Brannigan, J.A, Wilson, K.S, Wilkinson, A.J. Deposit date: 2004-09-30 Release date: 2005-10-04 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 A resolution. Proteins, 62, 2006
1XKY	Crystal Structure of Dihydrodipicolinate Synthase DapA-2 (BA3935) from Bacillus Anthracis at 1.94A Resolution. Descriptor: POTASSIUM ION, dihydrodipicolinate synthase Authors: Levdikov, V, Blagova, E, Fogg, M.J, Brannigan, J.A, Milioti, N, Wilkinson, A.J, Wilson, K.S. Deposit date: 2004-09-30 Release date: 2005-10-04 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 A resolution Proteins, 62, 2006
1XXX	Crystal structure of Dihydrodipicolinate Synthase (DapA, Rv2753c) from Mycobacterium tuberculosis Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, Dihydrodipicolinate synthase, ... Authors: Kefala, G, Panjikar, S, Janowski, R, Weiss, M.S, TB Structural Genomics Consortium (TBSGC) Deposit date: 2004-11-09 Release date: 2006-02-14 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis. Biochem.J., 411, 2008
1HL2	Crystal structure of N-acetylneuraminate lyase from E. coli mutant L142R in complex with b-hydroxypyruvate Descriptor: 3-HYDROXYPYRUVIC ACID, N-ACETYLNEURAMINATE LYASE SUBUNIT Authors: Joerger, A.C, Fersht, A.R. Deposit date: 2003-03-12 Release date: 2003-05-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Mimicking Natural Evolution in Vitro: An N-Acetylneuraminate Lyase Mutant with an Increased Dihydrodipicolinate Synthase Activity Proc.Natl.Acad.Sci.USA, 100, 2003
1YXD	Structure of E. coli dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine to 2.0 A Descriptor: CHLORIDE ION, LYSINE, POTASSIUM ION, ... Authors: Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. Deposit date: 2005-02-20 Release date: 2005-08-02 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2 Å) Cite: The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance. Acta Crystallogr.,Sect.D, 61, 2005
1YXC	Structure of E. coli dihydrodipicolinate synthase to 1.9 A Descriptor: CHLORIDE ION, POTASSIUM ION, dihydrodipicolinate synthase Authors: Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. Deposit date: 2005-02-20 Release date: 2005-08-02 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance. Acta Crystallogr.,Sect.D, 61, 2005
4M19	dihydrodipicolinate synthase from C. jejuni with pyruvate bound to the active site and Lysine bound to allosteric site Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, DI(HYDROXYETHYL)ETHER, ... Authors: Conly, C.J.T. Deposit date: 2013-08-02 Release date: 2015-01-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine. Biochemistry, 53, 2014
4LY8	dihydrodipicolinate synthase from C. jejuni with pyruvate bound to the active site Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ... Authors: Conly, C.J.T. Deposit date: 2013-07-30 Release date: 2015-01-14 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine. Biochemistry, 53, 2014
2A6L	Dihydrodipicolinate synthase (E. coli)- mutant R138H Descriptor: Dihydrodipicolinate synthase, POTASSIUM ION Authors: Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A. Deposit date: 2005-07-03 Release date: 2005-10-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase. Biochemistry, 44, 2005
2A6N	Dihydrodipicolinate synthase (E. coli)- mutant R138A Descriptor: Dihydrodipicolinate synthase, POTASSIUM ION Authors: Dobson, R.C, Devenish, S.R, Turner, L.A, Clifford, V.R, Pearce, F.G, Jameson, G.B, Gerrard, J.A. Deposit date: 2005-07-03 Release date: 2005-10-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase. Biochemistry, 44, 2005
4MLR	dihydrodipicolinate synthase from C. jejuni, Y110F mutation with pyruvate and Lysine Descriptor: 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ... Authors: Conly, C.J.T. Deposit date: 2013-09-06 Release date: 2015-01-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine. Biochemistry, 53, 2014
4MPQ	Crystal structure of1-pyrroline-4-hydroxy-2-carboxylate deaminase from Brucella melitensis ATCC 23457 Descriptor: 1,2-ETHANEDIOL, Dihydrodipicolinate synthetase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-09-13 Release date: 2013-09-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal structure of1-pyrroline-4-hydroxy-2-carboxylate deaminase from Brucella melitensis ATCC 23457 To be Published
2ATS	Dihydrodipicolinate synthase co-crystallised with (S)-lysine Descriptor: CHLORIDE ION, D-LYSINE, POTASSIUM ION, ... Authors: Devenish, S.R.A, Dobson, R.C.J, Jameson, G.B, Gerrard, J.A. Deposit date: 2005-08-26 Release date: 2006-09-19 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The co-crystallisation of (S)-lysine-bound dihydrodipicolinate synthase from E. coli indicates that domain movements are not responsible for (S)-lysine inhibition To be published
4MLJ	dihydrodipicolinate synthase from C. jejuni, Y110F mutation with pyruvate bound to the active site Descriptor: 1,2-ETHANEDIOL, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... Authors: Conly, C.J.T. Deposit date: 2013-09-06 Release date: 2015-01-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine. Biochemistry, 53, 2014
4N4P	Crystal Structure of N-acetylneuraminate lyase from Mycoplasma synoviae, crystal form I Descriptor: Acylneuraminate lyase, CHLORIDE ION Authors: Georgescauld, F, Popova, K, Gupta, A.J, Bracher, A, Engen, J.R, Hayer-Hartl, M, Hartl, F.U. Deposit date: 2013-10-08 Release date: 2014-05-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: GroEL/ES chaperonin modulates the mechanism and accelerates the rate of TIM-barrel domain folding. Cell(Cambridge,Mass.), 157, 2014
4N4Q	Crystal Structure of N-acetylneuraminate lyase from Mycoplasma synoviae, crystal form II Descriptor: Acylneuraminate lyase Authors: Georgescauld, F, Popova, K, Gupta, A.J, Bracher, A, Engen, J.R, Hayer-Hartl, M, Hartl, F.U. Deposit date: 2013-10-08 Release date: 2014-05-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: GroEL/ES Chaperonin Modulates the Mechanism and Accelerates the Rate of TIM-Barrel Domain Folding. Cell(Cambridge,Mass.), 157, 2014
4O0K	Crystal structure of 1-pyrroline-4-hydroxy-2-carboxylate deaminase from Brucella melitensis with covalently bound substrate Descriptor: 1,2-ETHANEDIOL, Dihydrodipicolinate synthetase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-12-13 Release date: 2014-01-15 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of 1-pyrroline-4-hydroxy-2-carboxylate deaminase from Brucella melitensis with covalently bound substrate To be Published
2YXG	Crystal structure of Dihyrodipicolinate Synthase (dapA) Descriptor: Dihydrodipicolinate synthase Authors: Padmanabhan, B, Bessho, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-04-26 Release date: 2007-10-30 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of dihydrodipicolinate synthase from Methanocaldococcus jannaschii. Acta Crystallogr.,Sect.F, 65, 2009
2YDA	Sulfolobus sulfataricus 2-keto-3-deoxygluconate aldolase Y103F,Y130F, A198F variant Descriptor: 2-KETO-3-DEOXY GLUCONATE ALDOLASE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... Authors: Crennell, S.J, Royer, S.F, Angelopoulou, M, Hough, D.W, Danson, M.J, Bull, S.D. Deposit date: 2011-03-18 Release date: 2012-03-28 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Sulfolobus Sulfataricus 2-Keto-3-Deoxygluconate Aldolase To be Published
2YGY	Structure of wild type E. coli N-acetylneuraminic acid lyase in space group P21 crystal form II Descriptor: CHLORIDE ION, N-ACETYLNEURAMINATE LYASE, PENTAETHYLENE GLYCOL Authors: Campeotto, I, Nelson, A, Berry, A, Phillips, S.E.V, Pearson, A.R. Deposit date: 2011-04-23 Release date: 2012-04-04 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Pathological macromolecular crystallographic data affected by twinning, partial-disorder and exhibiting multiple lattices for testing of data processing and refinement tools. Sci Rep, 8, 2018
4DPP	The structure of dihydrodipicolinate synthase 2 from Arabidopsis thaliana Descriptor: Dihydrodipicolinate synthase 2, chloroplastic, SODIUM ION Authors: Griffin, M.D.W, Billakanti, J.M, Gerrard, J.A, Dobson, R.C.J, Pearce, F.G. Deposit date: 2012-02-14 Release date: 2012-07-18 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana Plos One, 7, 2012
4DPQ	The structure of dihydrodipicolinate synthase 2 from Arabidopsis thaliana in complex with (S)-lysine Descriptor: Dihydrodipicolinate synthase 2, chloroplastic, LYSINE, ... Authors: Griffin, M.D.W, Billakanti, J.M, Gerrard, J.A, Dobson, R.C.J, Pearce, F.G. Deposit date: 2012-02-14 Release date: 2012-07-18 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.202 Å) Cite: Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana Plos One, 7, 2012

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