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6VLR	BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20E1 and PGT122 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIPv5.2 gp41, ... Authors: Cottrell, C.A, Ward, A.B. Deposit date: 2020-01-24 Release date: 2020-06-24 Last modified: 2020-09-16 Method: ELECTRON MICROSCOPY (4.42 Å) Cite: Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. Plos Pathog., 16, 2020
6VN0	BG505 SOSIP.v4.1 in complex with rhesus macaque Fab RM20F Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... Authors: Cottrell, C.A, Shin, M, Ward, A.B. Deposit date: 2020-01-29 Release date: 2020-06-24 Last modified: 2020-09-16 Method: ELECTRON MICROSCOPY (4.25 Å) Cite: Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. Plos Pathog., 16, 2020
6VO0	BG505 SOSIP.v5.2 in complex with rabbit Fab 43A2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 43A2 heavy chain, ... Authors: Nogal, B, Cottrell, C.A, Ward, A.B. Deposit date: 2020-01-29 Release date: 2020-07-01 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.52 Å) Cite: HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite. Sci Adv, 6, 2020
6VO1	BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20J Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... Authors: Cottrell, C.A, Ward, A.B. Deposit date: 2020-01-29 Release date: 2020-07-01 Last modified: 2020-09-16 Method: ELECTRON MICROSCOPY (3.88 Å) Cite: Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. Plos Pathog., 16, 2020
6VPX	Nanodisc of full-length HIV-1 Envelope glycoprotein clone AMC011 in complex with one PGT151 Fab and three 10E8 Fabs Descriptor: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Rantalainen, K, Ward, A.B.W. Deposit date: 2020-02-04 Release date: 2020-04-22 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (5 Å) Cite: HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies. Cell Rep, 31, 2020
6VY2	Cryo-EM structure of M1214_N1 Fab in complex with CH505 TF chimeric SOSIP.664 Env trimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, ... Authors: Chan, K.-W, Kong, X.P. Deposit date: 2020-02-25 Release date: 2020-05-06 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (4.86 Å) Cite: VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA. Cell Host Microbe, 27, 2020
6VZI	Crystal Structure of HIV-1 CAP256 RnS-3mut-2G-SOSIP.664 Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ... Authors: Lai, Y.-T, Kwong, P.D. Deposit date: 2020-02-28 Release date: 2020-04-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.716 Å) Cite: Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses. J.Virol., 94, 2020
6W03	Crystal Structure of HIV-1 BG505 DS-SOSIP.3mut Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.3 Angstrom Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ... Authors: Lai, Y.-T, Kwong, P.D. Deposit date: 2020-02-28 Release date: 2020-04-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses. J.Virol., 94, 2020
6WIX	Crystal Structure of HIV-1 MI369 RnS-DS.SOSIP Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Lai, Y.-T, Olia, A, Kwong, P.D. Deposit date: 2020-04-10 Release date: 2020-11-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains. Cell Rep, 33, 2020
6X5B	Symmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with small molecule GO52 Descriptor: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Ozorowski, G, Torres, J.L, Ward, A.B. Deposit date: 2020-05-25 Release date: 2020-10-21 Last modified: 2020-12-09 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020
6X5C	Asymmetric model of CD4-bound B41 HIV-1 Env SOSIP in complex with small molecule GO52 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... Authors: Ozorowski, G, Torres, J.L, Ward, A.B. Deposit date: 2020-05-25 Release date: 2020-10-21 Last modified: 2020-12-09 Method: ELECTRON MICROSCOPY (4.04 Å) Cite: A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020
6X96	Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 10A fragment antigen binding variable domain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 HIV-1 Env gp120, ... Authors: Ozorowski, G, Cottrell, C.A, Ward, A.B. Deposit date: 2020-06-02 Release date: 2021-12-08 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions To Be Published
6X97	Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 11A fragment antigen binding variable domain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 HIV-1 Env gp120, ... Authors: Ozorowski, G, Cottrell, C.A, Ward, A.B. Deposit date: 2020-06-02 Release date: 2021-12-08 Method: ELECTRON MICROSCOPY (3.65 Å) Cite: Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions To Be Published
6X98	Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 11B fragment antigen binding variable domain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 HIV-1 Env gp120, ... Authors: Ozorowski, G, Cottrell, C.A, Ward, A.B. Deposit date: 2020-06-02 Release date: 2021-12-08 Method: ELECTRON MICROSCOPY (3.38 Å) Cite: Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions To Be Published
6X9R	HIV-1 Envelope Glycoprotein BG505 SOSIP.664 expressed in HEK293F cells in complex with RM20A3 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120, ... Authors: Berndsen, Z.T, Ward, A.B. Deposit date: 2020-06-03 Release date: 2020-11-04 Last modified: 2020-11-25 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Visualization of the HIV-1 Env glycan shield across scales. Proc.Natl.Acad.Sci.USA, 117, 2020
6X9S	HIV-1 Envelope Glycoprotein BG505 SOSIP.664 expressed in stable CHO cells in complex with RM20A3 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120, ... Authors: Berndsen, Z.T, Ward, A.B. Deposit date: 2020-06-03 Release date: 2020-11-04 Last modified: 2020-11-25 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Visualization of the HIV-1 Env glycan shield across scales. Proc.Natl.Acad.Sci.USA, 117, 2020
6X9T	HIV-1 Envelope Glycoprotein BG505 SOSIP.664 expressed in HEK293S cells in complex with RM20A3 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120, ... Authors: Berndsen, Z.T, Ward, A.B. Deposit date: 2020-06-03 Release date: 2020-11-04 Last modified: 2020-11-25 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Visualization of the HIV-1 Env glycan shield across scales. Proc.Natl.Acad.Sci.USA, 117, 2020
6X9U	HIV-1 Envelope Glycoprotein BG505 SOSIP.664, expressed in HEK293S cells and partially deglycosylated by endoglycosidase H, in complex with RM20A3 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120, ... Authors: Berndsen, Z.T, Ward, A.B. Deposit date: 2020-06-03 Release date: 2020-11-04 Last modified: 2020-11-25 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Visualization of the HIV-1 Env glycan shield across scales. Proc.Natl.Acad.Sci.USA, 117, 2020
6X9V	HIV-1 Envelope Glycoprotein BG505 SOSIP.664, expressed in HEK293S cells and deglycosylated by endoglycosidase H, in complex with RM20A3 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120, ... Authors: Berndsen, Z.T, Ward, A.B. Deposit date: 2020-06-03 Release date: 2020-11-04 Last modified: 2020-11-25 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Visualization of the HIV-1 Env glycan shield across scales. Proc.Natl.Acad.Sci.USA, 117, 2020
6XRT	Cryo-EM structure of SHIV-elicited RHA1.V2.01 in complex with HIV-1 Env BG505 DS-SOSIP.664 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2020-07-13 Release date: 2020-10-07 Last modified: 2021-01-20 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science, 371, 2021
7AEJ	Crystal structure of asymmetric HIV-1 gp41 containing all membrane anchors Descriptor: 2H10, Envelope glycoprotein gp160,Envelope glycoprotein gp160 Authors: Caillat, C, Guilligay, D, Weissenhorn, W. Deposit date: 2020-09-17 Release date: 2021-05-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies. Elife, 10, 2021
7KDE	BG505 SOSIP.664 in complex with the V3-targeting rhesus macaque antibody 1485 and human gp120-gp41 interface antibody 8ANC195 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Barnes, C.O, Bjorkman, P.J. Deposit date: 2020-10-08 Release date: 2020-10-28 Last modified: 2020-11-04 Method: ELECTRON MICROSCOPY (3.55 Å) Cite: A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch. Elife, 9, 2020
7L6O	Cryo-EM structure of HIV-1 Env CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 - gp120, ... Authors: Manne, K, Edwards, R.J, Acharya, P. Deposit date: 2020-12-23 Release date: 2021-04-14 Last modified: 2021-06-09 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021
7L7T	BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component A) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ... Authors: Antanasijevic, A, Cannac, F, Sewall, L.M, Ward, A.B. Deposit date: 2020-12-30 Release date: 2021-08-04 Last modified: 2021-08-25 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM. Nat Commun, 12, 2021
7L7U	BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component B) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ... Authors: Antanasijevic, A, Froes Rocha, R, Sewall, L.M, Ward, A.B. Deposit date: 2020-12-30 Release date: 2021-08-04 Last modified: 2021-08-25 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM. Nat Commun, 12, 2021

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