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5DUR	Influenza A virus H5 hemagglutinin globular head in complex with antibody 100F4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Antibody 100F4, Hemagglutinin, ... Authors: Zuo, T, Sun, J, Wang, G, Zhou, P, Wang, X, Zhang, L. Deposit date: 2015-09-20 Release date: 2015-12-16 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.82 Å) Cite: Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection Nat Commun, 6, 2015
5DUM	Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody 65C6 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 65C6 Heavy Chain, 65C6 Light Chain, ... Authors: Sun, J, Zuo, T, Wang, G, Zhou, P, Zhang, L, Wang, X. Deposit date: 2015-09-19 Release date: 2015-12-16 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3.003 Å) Cite: Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection Nat Commun, 6, 2015
5E2Y	Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/duck/Egypt/10185SS/2010 (H5N1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Zhu, X, Wilson, I.A. Deposit date: 2015-10-01 Release date: 2015-12-02 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants. Cell Rep, 13, 2015
5E32	Crystal structure of H5 hemagglutinin mutant (N224K, Q226L, N158D and L133a deletion) from the influenza virus A/chicken/Vietnam/NCVD-093/2008 (H5N1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin Authors: Zhu, X, Wilson, I.A. Deposit date: 2015-10-01 Release date: 2015-12-02 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants. Cell Rep, 13, 2015
5GJT	Crystal structure of H1 hemagglutinin from A/Washington/05/2011 in complex with a neutralizing antibody 3E1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, heavy chain of human neutralizing antibody 3E1, ... Authors: Wang, W, Zhang, T, Ding, J. Deposit date: 2016-07-01 Release date: 2016-12-07 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses Nat Commun, 7, 2016
5GJS	Crystal structure of H1 hemagglutinin from A/California/04/2009 in complex with a neutralizing antibody 3E1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... Authors: Wang, W, Zhang, T, Ding, J. Deposit date: 2016-07-01 Release date: 2016-12-07 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses Nat Commun, 7, 2016
8TP5	H1 hemagglutinin (NC99) in complex with RBS-targeting Fab 1-1-1E04 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1E04, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TP7	H2 hemagglutinin (A/Singapore/1/1957) in complex with Sa-targeting Fab 4-1-1G03 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of monoclonal antibody 4-1-1G03, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TPA	H1 hemagglutinin (NC99) in complex with medial-junction-targeting Fab 2-2-1G06 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 2-2-1G06, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (3 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TP2	H2 hemagglutinin (A/Singapore/1/1957) in complex with RBS-targeting 1-1-1F05 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1F05, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TP4	H2 hemagglutinin (A/Singapore/1/1957) in complex with RBS-targeting Fab 1-1-1E04 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1E04, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TP3	H1 hemagglutinin (NC99) in complex with RBS-targeting Fab 1-1-1F05 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 1-1-1F05, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TP9	H2 hemagglutinin (A/Singapore/1/1957) in complex with medial-junction-targeting Fab 2-2-1G06 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 2-2-1G06, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8TP6	H2 hemagglutinin (A/Singapore/1/1957) in complex with RBS-targeting Fab 4-1-1E02 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 4-1-1E02 Fab, ... Authors: Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. Deposit date: 2023-08-04 Release date: 2023-10-11 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
8SK7	Cryo-EM structure of designed Influenza HA binder, HA_20, bound to Influenza HA (Strain: Iowa43) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HA_20 minibinder (RFdiffusion-designed), ... Authors: Borst, A.J, Bennett, N.R. Deposit date: 2023-04-18 Release date: 2023-06-14 Last modified: 2023-09-13 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: De novo design of protein structure and function with RFdiffusion. Nature, 620, 2023
8UR7	I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-6heptad-I53_dn5 (local refinement of TH-6heptad) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain Authors: Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-10-25 Release date: 2023-12-27 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Antigen spacing on protein nanoparticles influences antibody responses to vaccination. Cell Rep, 42, 2023
8UR5	I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-1heptad-I53_dn5 (local refinement of TH-1heptad) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain Authors: Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-10-25 Release date: 2023-12-27 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Antigen spacing on protein nanoparticles influences antibody responses to vaccination. Cell Rep, 42, 2023
8TJA	CRYSTAL STRUCTURE OF THE A/Ecuador/1374/2016(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8TJ6	CRYSTAL STRUCTURE OF THE A/Beijing/353/1989(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8TJB	CRYSTAL STRUCTURE OF THE A/Texas/73/2017(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8TJ4	CRYSTAL STRUCTURE OF THE A/Bangkok/1/1979(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8TJ8	CRYSTAL STRUCTURE OF THE A/Moscow/10/1999(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.56 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8TJ9	CRYSTAL STRUCTURE OF THE A/Michigan/15/2014(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8TJ7	CRYSTAL STRUCTURE OF THE A/Shandong/9/1993(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2023-07-20 Release date: 2024-02-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
8V7O	Fab fragment of human mAb #58 in complex with computationally optimized broadly reactive H1 influenza hemagglutinin X6 Descriptor: #58 heavy chain, #58 light chain, Hemagglutinin Authors: Nagashima, K.A, Mousa, J.J. Deposit date: 2023-12-04 Release date: 2024-04-10 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6 To Be Published

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