PDB: 1313 resultsInfo pagesStatus searchChemie searchBIRD

---

1CNJ	X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Lesburg, C.A, Christianson, D.W. Deposit date: 1995-04-03 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site J.Am.Chem.Soc., 117, 1995
1CNK	X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE Descriptor: CARBONIC ANHYDRASE II, SULFATE ION, ZINC ION Authors: Lesburg, C.A, Christianson, D.W. Deposit date: 1995-04-03 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.15 Å) Cite: X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site J.Am.Chem.Soc., 117, 1995
1CNH	X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Lesburg, C.A, Christianson, D.W. Deposit date: 1995-04-03 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.05 Å) Cite: X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site J.Am.Chem.Soc., 117, 1995
1CNG	X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE Descriptor: CARBONIC ANHYDRASE II, CHLORIDE ION, ZINC ION Authors: Lesburg, C.A, Christianson, D.W. Deposit date: 1995-04-03 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site J.Am.Chem.Soc., 117, 1995
1CNY	SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, PHENYLALANYLAMINODI(ETHYLOXY)ETHYL BENZENESULFONAMIDEAMINOCARBONYLBENZENESULFONAMIDE, ... Authors: Boriack, P.A, Christianson, D.W. Deposit date: 1995-07-21 Release date: 1995-11-14 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants. J.Med.Chem., 38, 1995
1CNW	SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS Descriptor: AMINOMETHYLENECARBONYLAMINODI(ETHYLOXY)ETHYLAMINOCARBONYLBENZENESULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Boriack, P.A, Christianson, D.W. Deposit date: 1995-07-21 Release date: 1995-11-14 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants. J.Med.Chem., 38, 1995
1CNX	SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS Descriptor: AMINODI(ETHYLOXY)ETHYLAMINOCARBONYLBENZENESULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Boriack, P.A, Christianson, D.W. Deposit date: 1995-07-21 Release date: 1995-11-14 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants. J.Med.Chem., 38, 1995
1DMY	COMPLEX BETWEEN MURINE MITOCHONDRIAL CARBONIC ANYHDRASE V AND THE TRANSITION STATE ANALOGUE ACETAZOLAMIDE Descriptor: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, MURINE CARBONIC ANHYDRASE V, ZINC ION Authors: Boriack-Sjodin, P.A, Christianson, D.W. Deposit date: 1995-10-04 Release date: 1996-04-03 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-A resolution: implications for catalytic proton transfer and inhibitor design. Proc.Natl.Acad.Sci.USA, 92, 1995
1DMX	MURINE MITOCHONDRIAL CARBONIC ANYHDRASE V AT 2.45 ANGSTROMS RESOLUTION Descriptor: MURINE CARBONIC ANHYDRASE V, ZINC ION Authors: Boriack-Sjodin, P.A, Christianson, D.W. Deposit date: 1995-10-04 Release date: 1996-04-03 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-A resolution: implications for catalytic proton transfer and inhibitor design. Proc.Natl.Acad.Sci.USA, 92, 1995
1ZSB	CARBONIC ANHYDRASE II MUTANT E117Q, TRANSITION STATE ANALOGUE ACETAZOLAMIDE Descriptor: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CARBONIC ANHYDRASE II, ZINC ION Authors: Lesburg, C.A, Christianson, D.W. Deposit date: 1996-01-09 Release date: 1996-07-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II. Biochemistry, 35, 1996
1ZSC	CARBONIC ANHYDRASE II MUTANT E117Q, HOLO FORM Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Lesburg, C.A, Christianson, D.W. Deposit date: 1996-01-09 Release date: 1996-07-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II. Biochemistry, 35, 1996
1ZSA	CARBONIC ANHYDRASE II MUTANT E117Q, APO FORM Descriptor: CARBONIC ANHYDRASE II Authors: Lesburg, C.A, Christianson, D.W. Deposit date: 1996-01-09 Release date: 1996-07-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II. Biochemistry, 35, 1996
1OKM	CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKM INHIBITOR 4-SULFONAMIDE-[1-(4-AMINOBUTANE)]BENZAMIDE Descriptor: 4-SULFONAMIDE-[1-(4-AMINOBUTANE)]BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Elbaum, D, Nair, S.K, Patchan, M.W, Thompson, R.B, Christianson, D.W. Deposit date: 1996-06-25 Release date: 1997-01-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure-based design of a sulfonamide probe for fluorescence anisotropy detection of zinc with a carbonic anhydrase-based biosensor. J.Am.Chem.Soc., 118, 1996
1OKL	CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKL INHIBITOR 5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONAMIDE Descriptor: 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Nair, S.K, Elbaum, D, Christianson, D.W. Deposit date: 1996-06-25 Release date: 1997-01-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Unexpected binding mode of the sulfonamide fluorophore 5-dimethylamino-1-naphthalene sulfonamide to human carbonic anhydrase II. Implications for the development of a zinc biosensor. J.Biol.Chem., 271, 1996
1OKN	CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKN INHIBITOR 4-SULFONAMIDE-[1-(4-N-(5-FLUORESCEIN THIOUREA)BUTANE)] Descriptor: 4-SULFONAMIDE-[4-(THIOMETHYLAMINOBUTANE)]BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Elbaum, D, Nair, S.K, Patchan, M.W, Thompson, R.B, Christianson, D.W. Deposit date: 1996-06-25 Release date: 1997-01-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure-based design of a sulfonamide probe for fluorescence anisotropy detection of zinc with a carbonic anhydrase-based biosensor. J.Am.Chem.Soc., 118, 1996
1URT	MURINE CARBONIC ANHYDRASE V Descriptor: CARBONIC ANHYDRASE V, ZINC ION Authors: Boriack-Sjodin, P.A, Christianson, D.W. Deposit date: 1996-07-03 Release date: 1997-01-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure-based design of an intramolecular proton transfer site in murine carbonic anhydrase V. Biochemistry, 35, 1996
1UGE	HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY LEU (A65L) Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Scolnick, L.R, Christianson, D.W. Deposit date: 1996-07-24 Release date: 1997-04-01 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1UGD	HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY SER (A65S) Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Scolnick, L.R, Christianson, D.W. Deposit date: 1996-07-24 Release date: 1997-01-27 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1UGB	HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY GLY (A65G) Descriptor: AZIDE ION, CARBONIC ANHYDRASE II, ZINC ION Authors: Scolnick, L.R, Christianson, D.W. Deposit date: 1996-07-24 Release date: 1997-01-27 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1UGG	HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY SER (A65S)-ORTHORHOMBIC FORM Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Scolnick, L.R, Christianson, D.W. Deposit date: 1996-07-24 Release date: 1997-01-27 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1UGF	HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY THR (A65T) Descriptor: AZIDE ION, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... Authors: Scolnick, L.R, Christianson, D.W. Deposit date: 1996-07-24 Release date: 1997-04-01 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1UGA	HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY PHE (A65F) Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Scolnick, L.R, Christianson, D.W. Deposit date: 1996-07-24 Release date: 1997-01-27 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1UGC	HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY HIS (A65H) Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION Authors: Scolnick, L.R, Christianson, D.W. Deposit date: 1996-07-24 Release date: 1997-04-01 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1ZNC	HUMAN CARBONIC ANHYDRASE IV Descriptor: CARBONIC ANHYDRASE IV, SULFATE ION, ZINC ION Authors: Stams, T, Christianson, D.W. Deposit date: 1996-09-17 Release date: 1997-09-17 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of the secretory form of membrane-associated human carbonic anhydrase IV at 2.8-A resolution. Proc.Natl.Acad.Sci.USA, 93, 1996
1H9Q	H119Q CARBONIC ANHYDRASE II Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Lesburg, C.A, Christianson, D.W. Deposit date: 1997-05-29 Release date: 1997-09-17 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Histidine --> carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activity. Biochemistry, 36, 1997

<12345678910111213141516>