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6H1V
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BU of 6h1v by Molmil
The crystal structure of Pol2CORE in complex with DNA and an incoming nucleotide, carrying an Fe-S cluster
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(P*AP*AP*TP*TP*GP*AP*AP*CP*GP*CP*GP*GP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*CP*CP*GP*CP*GP*TP*TP*(DOC))-3'), ...
Authors:Parkash, V, Johansson, E.
Deposit date:2018-07-12
Release date:2019-04-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural evidence for an essential Fe-S cluster in the catalytic core domain of DNA polymerase ε.
Nucleic Acids Res., 47, 2019
8KG8
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BU of 8kg8 by Molmil
Yeast replisome in state II
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ...
Authors:Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
Deposit date:2023-08-17
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (4.23 Å)
Cite:Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
8KG6
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BU of 8kg6 by Molmil
Yeast replisome in state I
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ...
Authors:Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
Deposit date:2023-08-17
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
8KG9
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BU of 8kg9 by Molmil
Yeast replisome in state III
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ...
Authors:Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
Deposit date:2023-08-17
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (4.52 Å)
Cite:Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
8OJ7
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BU of 8oj7 by Molmil
HSV-1 DNA polymerase-processivity factor complex in halted elongation state
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (53-MER), DNA (67-MER), ...
Authors:Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
Deposit date:2023-03-24
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.46 Å)
Cite:Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM
To Be Published
8OJ6
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BU of 8oj6 by Molmil
HSV-1 DNA polymerase-processivity factor complex in pre-translocation state
Descriptor: DNA (22-MER), DNA (48-MER), DNA polymerase catalytic subunit, ...
Authors:Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
Deposit date:2023-03-24
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.41 Å)
Cite:Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM
To Be Published
8OJC
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BU of 8ojc by Molmil
HSV-1 DNA polymerase active site in alternative exonuclease state
Descriptor: CALCIUM ION, DNA (47-MER), DNA polymerase catalytic subunit
Authors:Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
Deposit date:2023-03-24
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.08 Å)
Cite:Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM
To Be Published
8OJB
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BU of 8ojb by Molmil
HSV-1 DNA polymerase-processivity factor complex in exonuclease state active site
Descriptor: CALCIUM ION, DNA (47-MER), DNA polymerase catalytic subunit
Authors:Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
Deposit date:2023-03-24
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (1.9 Å)
Cite:Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM
To Be Published
8OJA
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BU of 8oja by Molmil
HSV-1 DNA polymerase-processivity factor complex in exonuclease state
Descriptor: CALCIUM ION, DNA (47-MER), DNA (68-MER), ...
Authors:Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
Deposit date:2023-03-24
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (1.87 Å)
Cite:Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM
To Be Published
8OJD
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BU of 8ojd by Molmil
HSV-1 DNA polymerase beta-hairpin loop
Descriptor: CALCIUM ION, DNA (47-MER), DNA (68-MER), ...
Authors:Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M.
Deposit date:2023-03-24
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.46 Å)
Cite:Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM
To Be Published
8B9D
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BU of 8b9d by Molmil
Human replisome bound by Pol Alpha
Descriptor: Cell division control protein 45 homolog, Claspin, DNA Molecule, ...
Authors:Jones, M.L, Yeeles, J.T.P.
Deposit date:2022-10-05
Release date:2023-08-09
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8B9C
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BU of 8b9c by Molmil
S. cerevisiae pol alpha - replisome complex
Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
Authors:Jones, M.L, Yeeles, J.T.P.
Deposit date:2022-10-05
Release date:2023-08-09
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8B9B
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BU of 8b9b by Molmil
S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
Authors:Jones, M.L, Yeeles, J.T.P.
Deposit date:2022-10-05
Release date:2023-08-09
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8B9A
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BU of 8b9a by Molmil
S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
Authors:Jones, M.L, Yeeles, J.T.P.
Deposit date:2022-10-05
Release date:2023-08-09
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8B6K
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BU of 8b6k by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing dCTP in the polymerase active site
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
Authors:Parkash, V, Johansson, E.
Deposit date:2022-09-27
Release date:2023-10-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B67
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BU of 8b67 by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing CTP in the polymerase active site
Descriptor: ACETATE ION, CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Parkash, V, Johansson, E.
Deposit date:2022-09-26
Release date:2023-10-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B7E
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BU of 8b7e by Molmil
The crystal structure of N828V variant of DNA Pol Epsilon containing UTP in the polymerase active site
Descriptor: CALCIUM ION, DNA polymerase epsilon catalytic subunit A, GLYCEROL, ...
Authors:Parkash, V, Johansson, E.
Deposit date:2022-09-29
Release date:2023-10-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B79
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BU of 8b79 by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing UTP in the polymerase active site
Descriptor: ACETATE ION, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
Authors:Parkash, V, Johansson, E.
Deposit date:2022-09-29
Release date:2023-10-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B77
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BU of 8b77 by Molmil
The crystal structure of N828V variant of DNA Pol Epsilon containing dATP in the polymerase active site
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
Authors:Parkash, V, Johansson, E.
Deposit date:2022-09-29
Release date:2023-10-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B76
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BU of 8b76 by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing dTTP in the polymerase active site
Descriptor: ACETATE ION, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
Authors:Parkash, V, Johansson, E.
Deposit date:2022-09-28
Release date:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
3IAY
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BU of 3iay by Molmil
Ternary complex of DNA polymerase delta
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ...
Authors:Swan, M.K, Aggarwal, A.K.
Deposit date:2009-07-15
Release date:2009-09-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta
Nat.Struct.Mol.Biol., 16, 2009
3K5O
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BU of 3k5o by Molmil
Crystal structure of E.coli Pol II
Descriptor: DNA polymerase II
Authors:Yang, W, Wang, F.
Deposit date:2009-10-07
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
3K59
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BU of 3k59 by Molmil
Crystal structure of E.coli Pol II-normal DNA-dCTP ternary complex
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*GP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
3K5N
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BU of 3k5n by Molmil
Crystal structure of E.coli Pol II-abasic DNA binary complex
Descriptor: DNA (5'-D(*GP*TP*CP*CP*TP*GP*(3DR)*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*G)-3'), DNA polymerase II
Authors:Yang, W, Wang, F.
Deposit date:2009-10-07
Release date:2010-02-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
3K5M
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BU of 3k5m by Molmil
Crystal structure of E.coli Pol II-abasic DNA-ddGTP Lt(-2, 2) ternary complex
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*TP*GP*(3DR)P*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-07
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009

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數據於2024-05-01公開中

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