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6LUR
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BU of 6lur by Molmil
Human PUF60 UHM domain (thioredoxin fusion) in complex with a small molecule binder
Descriptor: 4-[2-[4-(aminomethyl)phenyl]phenyl]piperazin-2-one, Thioredoxin 1,Poly(U)-binding-splicing factor PUF60
Authors:Takahashi, M, Hanzawa, H.
Deposit date:2020-01-30
Release date:2020-04-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Revisiting biomolecular NMR spectroscopy for promoting small-molecule drug discovery.
J.Biomol.Nmr, 74, 2020
6TMK
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BU of 6tmk by Molmil
Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase dimer, composite model
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Muhleip, A, Kock Flygaard, R, Amunts, A.
Deposit date:2019-12-04
Release date:2020-12-16
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria.
Nat Commun, 12, 2021
6TMG
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BU of 6tmg by Molmil
Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase dimer, membrane region model
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ATPTG1, ...
Authors:Muhleip, A, Kock Flygaard, R, Amunts, A.
Deposit date:2019-12-04
Release date:2020-12-16
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria.
Nat Commun, 12, 2021
6TML
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BU of 6tml by Molmil
Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase hexamer, composite model
Descriptor: ATP synthase subunit alpha, ATP synthase subunit beta, ATP synthase subunit delta, ...
Authors:Muhleip, A, Kock Flygaard, R, Amunts, A.
Deposit date:2019-12-04
Release date:2020-12-16
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria.
Nat Commun, 12, 2021
6KIL
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BU of 6kil by Molmil
N21Q mutant thioredoxin from Halobacterium salinarum NRC-1
Descriptor: Thioredoxin
Authors:Arai, S, Shibazaki, C, Shimizu, R, Adachi, M, Ishibashi, M, Tokunaga, H, Tokunaga, M.
Deposit date:2019-07-19
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Catalytic mechanism and evolutional characteristics of thioredoxin from Halobacterium salinarum NRC-1.
Acta Crystallogr.,Sect.D, 76, 2020
6P7E
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BU of 6p7e by Molmil
Structure of T7 DNA Polymerase Bound to a Primer/Template DNA and a Peptide that Mimics the C-terminal Tail of the Primase-Helicase
Descriptor: ASP-THR-ASP-PHE peptide, DNA (25-MER), DNA (5'-D(P*GP*GP*CP*AP*GP*GP*TP*GP*GP*TP*CP*TP*TP*GP*CP*CP*GP*GP*TP*GP*A)-3'), ...
Authors:Foster, B.M, Rosenberg, D, Salvo, H, Stephens, K.L, Bintz, B.J, Hammel, M, Ellenberger, T, Gainey, M.D, Wallen, J.R.
Deposit date:2019-06-05
Release date:2020-03-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Combined Solution and Crystal Methods Reveal the Electrostatic Tethers That Provide a Flexible Platform for Replication Activities in the Bacteriophage T7 Replisome.
Biochemistry, 58, 2019
6NUP
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BU of 6nup by Molmil
Structure of thioredoxin (trxA) from Rickettsia prowazekii str. Madrid E.
Descriptor: CITRIC ACID, Thioredoxin
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-02-01
Release date:2019-02-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of thioredoxin (trxA) from Rickettsia prowazekii str. Madrid E.
to be published
6Q6V
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BU of 6q6v by Molmil
Crystal structure (trigonal form) of C36S mutant of thioredoxin h1 from Chlamydomonas reinhardtii
Descriptor: DI(HYDROXYETHYL)ETHER, Thioredoxin H-type
Authors:Fermani, S, Zaffagnini, M, Lemaire, S.D.
Deposit date:2018-12-11
Release date:2019-01-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Structural and Biochemical Insights into the Reactivity of Thioredoxin h1 fromChlamydomonas reinhardtii.
Antioxidants (Basel), 8, 2019
6Q6T
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BU of 6q6t by Molmil
Crystal structure (orthorombic form) of C36S mutant of thioredoxin h1 from Chlamydomonas reinhardtii
Descriptor: DI(HYDROXYETHYL)ETHER, Thioredoxin H-type
Authors:Fermani, S, Zaffagnini, M, Lemaire, S.D.
Deposit date:2018-12-11
Release date:2019-01-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (0.94 Å)
Cite:Structural and Biochemical Insights into the Reactivity of Thioredoxin h1 fromChlamydomonas reinhardtii.
Antioxidants (Basel), 8, 2019
6Q6U
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BU of 6q6u by Molmil
Crystal structure of C39S mutant of thioredoxin h1 from Chlamydomonas reinhardtii
Descriptor: Thioredoxin H-type
Authors:Fermani, S, Zaffagnini, M, Lemaire, S.D.
Deposit date:2018-12-11
Release date:2019-01-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural and Biochemical Insights into the Reactivity of Thioredoxin h1 fromChlamydomonas reinhardtii.
Antioxidants (Basel), 8, 2019
6Q47
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BU of 6q47 by Molmil
Crystal structure of partially oxidized thioredoxin h1 from Chlamydomonas reinhardtii
Descriptor: Thioredoxin H-type
Authors:Fermani, S, Zaffagnini, M, Lemaire, S.D.
Deposit date:2018-12-05
Release date:2019-01-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural and Biochemical Insights into the Reactivity of Thioredoxin h1 fromChlamydomonas reinhardtii.
Antioxidants (Basel), 8, 2019
6Q46
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BU of 6q46 by Molmil
Crystal structure of reduced thioredoxin h1 from Chlamydomonas reinhardtii
Descriptor: Thioredoxin H-type
Authors:Fermani, S, Zaffagnini, M, Lemaire, S.D.
Deposit date:2018-12-05
Release date:2019-01-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Biochemical Insights into the Reactivity of Thioredoxin h1 fromChlamydomonas reinhardtii.
Antioxidants (Basel), 8, 2019
6IBL
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BU of 6ibl by Molmil
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND AGONIST FORMOTEROL AND NANOBODY Nb80
Descriptor: Camelid antibody fragment Nb80, HEGA-10, SODIUM ION, ...
Authors:Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G.
Deposit date:2018-11-30
Release date:2019-01-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of beta-arrestin coupling to formoterol-bound beta1-adrenoceptor.
Nature, 583, 2020
6N7W
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BU of 6n7w by Molmil
Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes)
Descriptor: DNA (25-MER), DNA (77-MER), DNA-directed DNA polymerase, ...
Authors:Gao, Y, Fox, T, Val, N, Yang, W.
Deposit date:2018-11-28
Release date:2019-03-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6I7S
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BU of 6i7s by Molmil
Microsomal triglyceride transfer protein
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ...
Authors:Biterova, E, Isupov, M.N, Keegan, R.M, Lebedev, A.A, Ruddock, L.W.
Deposit date:2018-11-17
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of human microsomal triglyceride transfer protein.
Proc.Natl.Acad.Sci.USA, 116, 2019
6MZA
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BU of 6mza by Molmil
Solution NMR structure of a putative thioredoxin (trxA) in the reduced state from Rickettsia prowazekii, the etiological agent responsible for typhus. Seattle Structural Genomics Center for Infectious Disease target RiprA.00029.a
Descriptor: Thioredoxin
Authors:Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-11-04
Release date:2018-12-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution NMR structure of reduced Rickettsia prowazekii thioredoxin.
To Be Published
6I1C
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BU of 6i1c by Molmil
Crystal structure of Chlamydomonas reinhardtii thioredoxin f2
Descriptor: thioredoxin f2
Authors:Lemaire, S.D, Tedesco, D, Crozet, P, Michelet, L, Fermani, S, Zaffagnini, M, Henri, J.
Deposit date:2018-10-28
Release date:2018-12-05
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal Structure of Chloroplastic Thioredoxin f2 fromChlamydomonas reinhardtiiReveals Distinct Surface Properties.
Antioxidants (Basel), 7, 2018
6I19
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BU of 6i19 by Molmil
Crystal structure of Chlamydomonas reinhardtii thioredoxin h1
Descriptor: Thioredoxin H-type
Authors:Lemaire, S.D, Tedesco, D, Crozet, P, Michelet, L, Fermani, S, Zaffagnini, M, Henri, J.
Deposit date:2018-10-27
Release date:2018-12-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.378 Å)
Cite:Crystal Structure of Chloroplastic Thioredoxin f2 fromChlamydomonas reinhardtiiReveals Distinct Surface Properties.
Antioxidants (Basel), 7, 2018
6MOS
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BU of 6mos by Molmil
Structure of thioredoxin 1 from the thermophilic eubacterium Thermosipho africanus TCF52B
Descriptor: TRIS(HYDROXYETHYL)AMINOMETHANE, Thioredoxin
Authors:Sahtout, N, Kuttiyatveetil, J.R, Sanders, D.A.R.
Deposit date:2018-10-04
Release date:2019-08-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.80013728 Å)
Cite:Structure and function of the putative thioredoxin 1 from the thermophilic eubacterium Thermosipho africanus strain TCF52B.
Biochim Biophys Acta Proteins Proteom, 1867, 2019
6HF1
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BU of 6hf1 by Molmil
Mutant oxidoreductase fragment of mouse QSOX1 in complex with an antibody Fab
Descriptor: Fab 316 heavy chain, Fab 316 light chain, Sulfhydryl oxidase 1
Authors:Grossman-Haham, I, Fass, D.
Deposit date:2018-08-21
Release date:2019-04-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:cis-Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures.
Protein Sci., 28, 2019
6H7J
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BU of 6h7j by Molmil
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND AGONIST ISOPRENALINE AND NANOBODY Nb80
Descriptor: Beta-1 adrenergic receptor, Camelid antibody fragment Nb80, HEGA-10, ...
Authors:Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G.
Deposit date:2018-07-31
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis for high-affinity agonist binding in GPCRs.
Science, 364, 2019
6H7L
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BU of 6h7l by Molmil
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST DOBUTAMINE AND NANOBODY Nb6B9
Descriptor: Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, DOBUTAMINE, ...
Authors:Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G.
Deposit date:2018-07-31
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis for high-affinity agonist binding in GPCRs.
Science, 364, 2019
6H7O
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BU of 6h7o by Molmil
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND WEAK PARTIAL AGONIST CYANOPINDOLOL AND NANOBODY Nb6B9
Descriptor: 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, ...
Authors:Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G.
Deposit date:2018-07-31
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis for high-affinity agonist binding in GPCRs.
Science, 364, 2019
6H7N
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BU of 6h7n by Molmil
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST XAMOTEROL AND NANOBODY Nb6B9
Descriptor: Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, HEGA-10, ...
Authors:Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G.
Deposit date:2018-07-31
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular basis for high affinity agonist binding in GPCRs
Biorxiv, 2018
6H7M
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BU of 6h7m by Molmil
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST SALBUTAMOL AND NANOBODY Nb6B9
Descriptor: Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, HEGA-10, ...
Authors:Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G.
Deposit date:2018-07-31
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Molecular basis for high-affinity agonist binding in GPCRs.
Science, 364, 2019

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