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2L1Z	NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures Descriptor: Insulin A chain, Insulin B chain Authors: Wan, Z.L, Hua, Q.X, Huang, K, Hu, S.Q, Philips, N.B, Katsoyannis, J.W, Weiss, M.A. Deposit date: 2010-08-09 Release date: 2011-08-31 Last modified: 2020-02-05 Method: SOLUTION NMR Cite: Chiral Protein Engineering and its Application in G Health To be Published
2L29	Complex structure of E4 mutant human IGF2R domain 11 bound to IGF-II Descriptor: Insulin-like growth factor 2 receptor variant, Insulin-like growth factor II Authors: Williams, C, Hoppe, H, Rezgui, D, Strickland, M, Frago, S, Ellis, R.Z, Wattana-Amorn, P, Prince, S.N, Zaccheo, O.J, Forbes, B, Jones, E.Y, Crump, M.P, Hassan, A.B. Deposit date: 2010-08-13 Release date: 2012-02-15 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution. Science, 338, 2012
2LGB	Modified A22Gly-B31Arg Human Insulin Descriptor: Insulin A chain, Insulin B chain Authors: Bocian, W, Kozerski, L. Deposit date: 2011-07-25 Release date: 2012-04-11 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus. J.Biomol.Nmr, 52, 2012
2LWZ	NMR Structures of Single-chain Insulin Descriptor: SINGLE-CHAIN INSULIN Authors: Weiss, M.A, Yang, Y. Deposit date: 2012-08-09 Release date: 2013-08-28 Method: SOLUTION NMR Cite: Dynamic repair of an amyloidogenic protein: Insulin fibrillation is blocked by tethering a nascent alpha-helix To be Published
2M1D	Biosynthetic engineered B28K-B29P human insulin monomer structure in in water/acetonitrile solutions. Descriptor: Insulin Authors: Bocian, W, Kozerski, L. Deposit date: 2012-11-26 Release date: 2013-02-27 Last modified: 2013-05-22 Method: SOLUTION NMR Cite: Biosynthetic engineered B28(K)-B29(P) human insulin monomer structure in water and in water/acetonitrile solutions. J.Biomol.Nmr, 55, 2013
2M1E	Biosynthetic engineered B28K-B29P human insulin monomer structure in in water solutions. Descriptor: Insulin Authors: Bocian, W, Kozerski, L. Deposit date: 2012-11-26 Release date: 2013-02-27 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Biosynthetic engineered B28(K)-B29(P) human insulin monomer structure in water and in water/acetonitrile solutions. J.Biomol.Nmr, 55, 2013
2M2M	Structure of [L-HisB24] insulin analogue at pH 1.9 Descriptor: Insulin A chain, Insulin B chain Authors: Zakova, L, Veverka, V, Jiracek, J. Deposit date: 2012-12-28 Release date: 2013-03-06 Last modified: 2013-06-05 Method: SOLUTION NMR Cite: Structural integrity of the B24 site in human insulin is important for hormone functionality. J.Biol.Chem., 288, 2013
2M2N	Structure of [L-HisB24] insulin analogue at pH 8.0 Descriptor: Insulin A chain, Insulin B chain Authors: Zakova, L, Veverka, V, Jiracek, J. Deposit date: 2012-12-29 Release date: 2013-03-06 Last modified: 2013-06-05 Method: SOLUTION NMR Cite: Structural integrity of the B24 site in human insulin is important for hormone functionality. J.Biol.Chem., 288, 2013
2M2O	Structure of [D-HisB24] insulin analogue at pH 1.9 Descriptor: Insulin A chain, Insulin B chain Authors: Zakova, L, Veverka, V, Jiracek, J. Deposit date: 2012-12-29 Release date: 2013-03-06 Last modified: 2013-06-05 Method: SOLUTION NMR Cite: Structural integrity of the B24 site in human insulin is important for hormone functionality. J.Biol.Chem., 288, 2013
2M2P	Structure of [D-HisB24] insulin analogue at pH 8.0 Descriptor: Insulin A chain, Insulin B chain Authors: Zakova, L, Veverka, V, Jiracek, J. Deposit date: 2012-12-29 Release date: 2013-03-06 Last modified: 2013-06-05 Method: SOLUTION NMR Cite: Structural integrity of the B24 site in human insulin is important for hormone functionality. J.Biol.Chem., 288, 2013
2MLI	NMR structure of B25-(alpha, beta)-dehydro-phenylalanine insulin Descriptor: Insulin Authors: Yang, Y, Weiss, M. Deposit date: 2014-02-27 Release date: 2014-08-20 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Protective hinge in insulin opens to enable its receptor engagement. Proc.Natl.Acad.Sci.USA, 111, 2014
2MPG	Solution structure of the [AibB8,LysB28,ProB29]-insulin analogue Descriptor: Insulin A chain, Insulin B chain Authors: Kosinova, L, Jiracek, J, Zakova, L, Veverka, V. Deposit date: 2014-05-17 Release date: 2014-06-11 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Insight into the structural and biological relevance of the T/R transition of the N-terminus of the B-chain in human insulin. Biochemistry, 53, 2014
2MPI	Solution structure of B24G insulin Descriptor: insulin chain A, insulin chain B Authors: Yang, Y, Wickramasinghe, N.P, Hua, Q, Weiss, M.A. Deposit date: 2014-05-19 Release date: 2014-12-24 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Protective hinge in insulin opens to enable its receptor engagement. Proc.Natl.Acad.Sci.USA, 111, 2014
2MVC	Solution structure of human insulin at pH 1.9 Descriptor: Insulin A chain, Insulin B chain Authors: Hexnerova, R, Krizkova, K, Maletinska, L, Jiracek, J, Brzozowski, A.M, Zakova, L, Veverka, V. Deposit date: 2014-10-02 Release date: 2014-12-10 Last modified: 2016-06-01 Method: SOLUTION NMR Cite: Structural and Functional Study of the GlnB22-Insulin Mutant Responsible for Maturity-Onset Diabetes of the Young. Plos One, 9, 2014
2MVD	Solution structure of [GlnB22]-insulin mutant at pH 1.9 Descriptor: Insulin A chain, Insulin B chain Authors: Hexnerova, R, Krizkova, K, Maletinska, L, Jiracek, J, Brzozowski, A.M, Zakova, L, Veverka, V. Deposit date: 2014-10-02 Release date: 2014-12-10 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structural and Functional Study of the GlnB22-Insulin Mutant Responsible for Maturity-Onset Diabetes of the Young. Plos One, 9, 2014
2N2V	Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 1.9 Descriptor: Insulin A chain, Insulin B chain Authors: Veverka, V, Hexnerova, R, Jiracek, J. Deposit date: 2015-05-15 Release date: 2016-02-03 Method: SOLUTION NMR Cite: Rational steering of insulin binding specificity by intra-chain chemical crosslinking. Sci Rep, 6, 2016
2N2W	Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 8.0 Descriptor: Insulin A chain, Insulin B chain Authors: Veverka, V, Hexnerova, R, Jiracek, J. Deposit date: 2015-05-15 Release date: 2016-02-03 Method: SOLUTION NMR Cite: Rational steering of insulin binding specificity by intra-chain chemical crosslinking. Sci Rep, 6, 2016
2N2X	Solution structure of [GlyB24,B27-B29 triazole cross-linked]-insulin analogue at pH 1.9 Descriptor: Insulin A chain, Insulin B chain Authors: Veverka, V, Hexnerova, R, Jiracek, J. Deposit date: 2015-05-15 Release date: 2016-02-03 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Rational steering of insulin binding specificity by intra-chain chemical crosslinking. Sci Rep, 6, 2016
2OLY	Structure of human insulin in presence of urea at pH 7.0 Descriptor: CHLORIDE ION, GLYCEROL, Insulin A chain, ... Authors: Norrman, M, Schluckebier, G. Deposit date: 2007-01-20 Release date: 2007-12-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH. Bmc Struct.Biol., 7, 2007
2OLZ	Structure of human insulin in presence of thiocyanate at pH 7.0 Descriptor: GLYCEROL, Insulin A, Insulin B, ... Authors: Norrman, M, Schluckebier, G. Deposit date: 2007-01-20 Release date: 2007-12-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH. Bmc Struct.Biol., 7, 2007
2OM0	Structure of human insulin in presence of urea at pH 6.5 Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Norrman, M, Schluckebier, G. Deposit date: 2007-01-20 Release date: 2007-12-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH. Bmc Struct.Biol., 7, 2007
2OM1	Structure of human insulin in presence of thiocyanate at pH 6.5 Descriptor: GLYCEROL, Insulin A chain, Insulin B chain, ... Authors: Norrman, M, Schluckebier, G. Deposit date: 2007-01-20 Release date: 2007-12-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH. Bmc Struct.Biol., 7, 2007
2OMG	Structure of human insulin cocrystallized with protamine and urea Descriptor: CHLORIDE ION, FORMAMIDE, Insulin A chain, ... Authors: Norrman, M, Schluckebier, G. Deposit date: 2007-01-22 Release date: 2007-03-27 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.52 Å) Cite: Structural characterization of insulin NPH formulations. EUR.J.PHARM.SCI., 30, 2007
2OMH	Structure of human insulin cocrystallized with ARG-12 peptide in presence of urea Descriptor: CHLORIDE ION, FORMAMIDE, Insulin A chain, ... Authors: Norrman, M, Schluckebier, G. Deposit date: 2007-01-22 Release date: 2007-03-27 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.36 Å) Cite: Structural characterization of insulin NPH formulations. EUR.J.PHARM.SCI., 30, 2007
2OMI	Structure of human insulin cocrystallized with protamine Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Norrman, M, Schluckebier, G. Deposit date: 2007-01-22 Release date: 2007-03-27 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Structural characterization of insulin NPH formulations. EUR.J.PHARM.SCI., 30, 2007

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