4CYD
 
 | | GlxR bound to cAMP | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, PROBABLE EXPRESSION TAG, ... | | Authors: | Townsend, P.D, Bott, M, Cann, M.J, Pohl, E. | | Deposit date: | 2014-04-10 | | Release date: | 2014-12-17 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | The Crystal Structures of Apo and Camp-Bound Glxr from Corynebacterium Glutamicum Reveal Structural and Dynamic Changes Upon Camp Binding in Crp/Fnr Family Transcription Factors.
Plos One, 9, 2014
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5K7L
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5JON
 | | Crystal structure of the unliganded form of HCN2 CNBD | | Descriptor: | Maltose-binding periplasmic protein,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, NITRATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Klenchin, V.A, Chanda, B. | | Deposit date: | 2016-05-02 | | Release date: | 2016-11-30 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.042 Å) | | Cite: | Structure and dynamics underlying elementary ligand binding events in human pacemaking channels.
Elife, 5, 2016
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4DIN
 | | Novel Localization and Quaternary Structure of the PKA RI beta Holoenzyme | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... | | Authors: | Ilouz, R, Bubis, J, Wu, J, Yim, Y.Y, Deal, M.S, Kornev, A.P, Ma, Y, Blumenthal, D.K, Taylor, S.S. | | Deposit date: | 2012-01-31 | | Release date: | 2012-07-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Localization and quaternary structure of the PKA RI Beta holoenzyme
Proc.Natl.Acad.Sci.USA, 109, 2012
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5JR7
 | | Crystal structure of an ACRDYS heterodimer [RIa(92-365):C] of PKA | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type I-alpha regulatory subunit | | Authors: | Bruystens, J.G.H, Wu, J, Taylor, S.S. | | Deposit date: | 2016-05-05 | | Release date: | 2017-03-15 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.56 Å) | | Cite: | Structure of a PKA RI alpha Recurrent Acrodysostosis Mutant Explains Defective cAMP-Dependent Activation.
J. Mol. Biol., 428, 2016
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8OTX
 | | Cryo-EM structure of Strongylocentrotus purpuratus sperm-specific Na+/H+ exchanger SLC9C1 in nanodisc | | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, Sperm-specific sodium proton exchanger | | Authors: | Yeo, H, Mehta, V, Gulati, A, Drew, D. | | Deposit date: | 2023-04-21 | | Release date: | 2023-11-01 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | Structure and electromechanical coupling of a voltage-gated Na + /H + exchanger.
Nature, 623, 2023
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8OTW
 | | Cryo-EM structure of Strongylocentrotus purpuratus SLC9C1 in presence of cAMP | | Descriptor: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Sperm-specific sodium proton exchanger | | Authors: | Yeo, H, Mehta, V, Gulati, A, Drew, D. | | Deposit date: | 2023-04-21 | | Release date: | 2023-11-01 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (3.68 Å) | | Cite: | Structure and electromechanical coupling of a voltage-gated Na + /H + exchanger.
Nature, 623, 2023
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8OTQ
 | | Cryo-EM structure of Strongylocentrotus purpuratus sperm-specific Na+/H+ exchanger SLC9C1 in GDN | | Descriptor: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, PALMITIC ACID, Sperm-specific sodium proton exchanger | | Authors: | Yeo, H, Mehta, V, Gulati, A, Drew, D. | | Deposit date: | 2023-04-21 | | Release date: | 2023-11-01 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (3.22 Å) | | Cite: | Structure and electromechanical coupling of a voltage-gated Na + /H + exchanger.
Nature, 623, 2023
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8PD8
 | | cAMP-bound SpSLC9C1 in lipid nanodiscs, dimer | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Sperm-specific sodium proton exchanger | | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | | Deposit date: | 2023-06-12 | | Release date: | 2023-11-08 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
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8PD9
 | | cAMP-bound SpSLC9C1 in lipid nanodiscs, protomer state 1 | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Sperm-specific sodium proton exchanger | | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | | Deposit date: | 2023-06-12 | | Release date: | 2023-11-08 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
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8PD5
 | | Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 3 | | Descriptor: | Sperm-specific sodium proton exchanger | | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | | Deposit date: | 2023-06-11 | | Release date: | 2023-11-08 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
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8PD2
 | | Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 1 | | Descriptor: | Sperm-specific sodium proton exchanger | | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | | Deposit date: | 2023-06-11 | | Release date: | 2023-11-08 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
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8PD7
 | | Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 4 | | Descriptor: | Sperm-specific sodium proton exchanger | | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | | Deposit date: | 2023-06-11 | | Release date: | 2023-11-08 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
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8PCZ
 | | Ligand-free SpSLC9C1 in lipid nanodiscs, dimer | | Descriptor: | Sperm-specific sodium proton exchanger | | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | | Deposit date: | 2023-06-11 | | Release date: | 2023-11-08 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.21 Å) | | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
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8PD3
 | | Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 2 | | Descriptor: | Sperm-specific sodium proton exchanger | | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | | Deposit date: | 2023-06-11 | | Release date: | 2023-11-08 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
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8PDU
 | | cGMP-bound SpSLC9C1 in lipid nanodiscs, dimer | | Descriptor: | CYCLIC GUANOSINE MONOPHOSPHATE, Sperm-specific sodium proton exchanger | | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | | Deposit date: | 2023-06-12 | | Release date: | 2023-11-08 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.22 Å) | | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
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4EV0
 | | Crystal Structure of Thermus thermophilus Catabolite Activator Protein | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MAGNESIUM ION, SULFATE ION, ... | | Authors: | Hudson, B.P, Turo, K, Birktoft, J.J, Lawson, C.L. | | Deposit date: | 2012-04-25 | | Release date: | 2012-06-20 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.402 Å) | | Cite: | Crystal Structure of T. thermophilius Catabolite Activator Protein
To be Published
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8PDV
 | | cGMP-bound SpSLC9C1 in lipid nanodiscs, protomer | | Descriptor: | CYCLIC GUANOSINE MONOPHOSPHATE, Sperm-specific sodium proton exchanger | | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | | Deposit date: | 2023-06-12 | | Release date: | 2023-11-08 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
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8QTO
 | | CRYSTAL STRUCTURE OF HOLO-L28H-FNR OF A. FISCHERI | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, FNR type regulator, IRON/SULFUR CLUSTER | | Authors: | Volbeda, A, Fontecilla-Camps, J.C. | | Deposit date: | 2023-10-13 | | Release date: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Probing the Reactivity of [4Fe-4S] Fumarate and Nitrate Reduction (FNR) Regulator with O2 and NO: Increased O2 Resistance and Relative Specificity for NO of the [4Fe-4S] L28H FNR Cluster
Inorganics (Basel), 11, 2023
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4F7Z
 | | Conformational dynamics of exchange protein directly activated by cAMP | | Descriptor: | GLYCEROL, Rap guanine nucleotide exchange factor 4 | | Authors: | White, M.A, Tsalkova, T.N, Mei, F.C, Liu, T, Woods, V.L, Cheng, X. | | Deposit date: | 2012-05-16 | | Release date: | 2012-10-03 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural analyses of a constitutively active mutant of exchange protein directly activated by cAMP.
Plos One, 7, 2012
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4FT8
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4I01
 | | Structure of the mutant Catabolite gen activator protein V140L | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator | | Authors: | Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M.J. | | Deposit date: | 2012-11-16 | | Release date: | 2013-10-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors.
Plos Biol., 11, 2013
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4I0A
 | | structure of the mutant Catabolite gene activator protein V132A | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, GLYCEROL | | Authors: | Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M.J. | | Deposit date: | 2012-11-16 | | Release date: | 2013-10-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors.
Plos Biol., 11, 2013
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4I09
 | | structure of the mutant Catabolite gene activator protein V132L | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator | | Authors: | Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M.J. | | Deposit date: | 2012-11-16 | | Release date: | 2013-10-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors.
Plos Biol., 11, 2013
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4HZF
 | | structure of the wild type Catabolite gene Activator Protein | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, GLYCEROL, ... | | Authors: | Pohl, E, Townsend, P.D, Rodgers, T, Burnell, D, McLeish, T.C.B, Wilson, M.R, Cann, M. | | Deposit date: | 2012-11-15 | | Release date: | 2013-10-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors.
Plos Biol., 11, 2013
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