PDB: 522 resultsInfo pagesStatus searchChemie searchBIRD

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5QU1	Crystal Structure of the monomeric human Nck SH3.1 domain, triclinic, 1.08A Descriptor: Cytoplasmic protein NCK1, SULFATE ION Authors: Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.08 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU5	Domain Swap in the first SH3 domain of human Nck1 Descriptor: Cytoplasmic protein NCK1 Authors: Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.11 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU2	Crystal Structure of human Nck SH3.1 in complex with peptide PPPVPNPDY Descriptor: ACE-PRO-PRO-PRO-VAL-PRO-ASN-PRO-ASP-TYR-NH2, Cytoplasmic protein NCK1, SULFATE ION Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.04 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU7	Crystal Structure of swapped human Nck SH3.1 domain, 1.3A, orthorhombic form III Descriptor: Cytoplasmic protein NCK1 Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.27 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU4	Crystal Structure of swapped human Nck SH3.1 domain, 1.05A, orthorhombic form I Descriptor: Cytoplasmic protein NCK1 Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.05 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
4IIM	Crystal structure of the Second SH3 Domain of ITSN1 bound with a synthetic peptide Descriptor: Intersectin-1, UNKNOWN ATOM OR ION, peptide ligand Authors: Dong, A, Guan, X, Huang, H, Wernimont, A, Gu, J, Sidhu, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) Deposit date: 2012-12-20 Release date: 2013-01-23 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the Second SH3 Domain of ITSN1 bound with a synthetic peptide To be Published
1ABO	CRYSTAL STRUCTURE OF THE COMPLEX OF THE ABL TYROSINE KINASE SH3 DOMAIN WITH 3BP-1 SYNTHETIC PEPTIDE Descriptor: 3BP-1 SYNTHETIC PEPTIDE, 10 RESIDUES, ABL TYROSINE KINASE, ... Authors: Musacchio, A, Wilmanns, M, Saraste, M. Deposit date: 1995-05-19 Release date: 1995-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nat.Struct.Biol., 1, 1994
4J9E	Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P17 Descriptor: P17, SULFATE ION, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P17 To be Published
1A0N	NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE COMPLEXED WITH THE SYNTHETIC PEPTIDE P2L CORRESPONDING TO RESIDUES 91-104 OF THE P85 SUBUNIT OF PI3-KINASE, FAMILY OF 25 STRUCTURES Descriptor: FYN, PRO-PRO-ARG-PRO-LEU-PRO-VAL-ALA-PRO-GLY-SER-SER-LYS-THR Authors: Renzoni, D.A, Pugh, D.J.R, Siligardi, G, Das, P, Morton, C.J, Rossi, C, Waterfield, M.D, Campbell, I.D, Ladbury, J.E. Deposit date: 1997-12-05 Release date: 1998-02-25 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase. Biochemistry, 35, 1996
4J9B	Crystal structure of the Abl-SH3 domain H59Q-N96T mutant Descriptor: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.702 Å) Cite: Crystal structure of the Abl-SH3 domain H59Q-N96T mutant To be Published
1AEY	ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, SOLUTION NMR, 15 STRUCTURES Descriptor: ALPHA-SPECTRIN Authors: Blanco, F.J, Ortiz, A.R, Serrano, L. Deposit date: 1997-03-02 Release date: 1997-05-15 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: 1H and 15N NMR assignment and solution structure of the SH3 domain of spectrin: comparison of unrefined and refined structure sets with the crystal structure. J.Biomol.NMR, 9, 1997
4JJB	Crystal structure of the Abl-SH3 domain at pH3 Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A, Martin-Garcia, J.M. Deposit date: 2013-03-07 Release date: 2014-03-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of the Abl-SH3 domain at pH3 To be Published
4J9D	Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P0 Descriptor: P0, SULFATE ION, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P0 To be Published
1ABQ	CRYSTAL STRUCTURE OF THE UNLIGANDED ABL TYROSINE KINASE SH3 DOMAIN Descriptor: ABL TYROSINE KINASE SRC-HOMOLOGY 3 (SH3) DOMAIN Authors: Musacchio, A, Wilmanns, M, Saraste, M. Deposit date: 1995-05-19 Release date: 1995-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.8 Å) Cite: High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nat.Struct.Biol., 1, 1994
4J9C	Crystal structure of the Abl-SH3 domain H59Q-N96T mutant complexed with the designed high-affinity peptide ligand P17 Descriptor: DI(HYDROXYETHYL)ETHER, P17, TRIETHYLENE GLYCOL, ... Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.051 Å) Cite: Crystal structure of the Abl-SH3 domain H59Q-N96T mutant complexed with the designed high-affinity peptide ligand P17 To be Published
4J9H	Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 at pH 8 Descriptor: P7, SULFATE ION, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 To be Published
4J9G	Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 at pH7 Descriptor: GLYCEROL, P7, SULFATE ION, ... Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 To be Published
1BBZ	CRYSTAL STRUCTURE OF THE ABL-SH3 DOMAIN COMPLEXED WITH A DESIGNED HIGH-AFFINITY PEPTIDE LIGAND: IMPLICATIONS FOR SH3-LIGAND INTERACTIONS Descriptor: ABL TYROSINE KINASE, PEPTIDE P41, SULFATE ION Authors: Pisabarro, M.T, Serrano, L, Wilmanns, M. Deposit date: 1998-04-28 Release date: 1998-11-25 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of the abl-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions. J.Mol.Biol., 281, 1998
4JJD	Crystal structure of the N114A Abl-SH3 domain mutant at pH4 Descriptor: DI(HYDROXYETHYL)ETHER, SODIUM ION, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A, Martin-Garcia, J.M. Deposit date: 2013-03-07 Release date: 2014-03-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of the Abl-SH3 domain at pH5 To be Published
1B07	CRK SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR Descriptor: PHENYLETHANE, PROTEIN (PROTO-ONCOGENE CRK (CRK)), PROTEIN (SH3 PEPTOID INHIBITOR) Authors: Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. Deposit date: 1998-11-17 Release date: 1999-01-06 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science, 282, 1998
4JJC	Crystal structure of the Abl-SH3 domain at pH5 Descriptor: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A, Martin-Garcia, J.M. Deposit date: 2013-03-07 Release date: 2014-03-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of the Abl-SH3 domain at pH5 To be Published
4J9F	Crystal structure of the Abl-SH3 domain complexed with the high affinity peptide P0 Descriptor: GLYCEROL, P0, SULFATE ION, ... Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.094 Å) Cite: Crystal structure of the Abl-SH3 domain complexed with the high affinity peptide P0 To be Published
4J9I	Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P17 Descriptor: GLYCEROL, P17, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P17 To be Published
1AWJ	INTRAMOLECULAR ITK-PROLINE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: ITK Authors: Andreotti, A.H, Bunnell, S.C, Feng, S, Berg, L.J, Schreiber, S.L. Deposit date: 1997-10-02 Release date: 1998-01-14 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Regulatory intramolecular association in a tyrosine kinase of the Tec family. Nature, 385, 1997
4JZ4	Crystal structure of chicken c-Src-SH3 domain: monomeric form Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A. Deposit date: 2013-04-02 Release date: 2014-04-23 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014

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