5OAV
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5OB2
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5OAZ
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5QU8
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5QU3
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5QUA
| Crystal Structure of swapped human Nck SH3.1 domain, 1.5A, C2221 | Descriptor: | Cytoplasmic protein NCK1 | Authors: | Rudolph, M.G. | Deposit date: | 2019-12-13 | Release date: | 2020-02-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
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5QU1
| Crystal Structure of the monomeric human Nck SH3.1 domain, triclinic, 1.08A | Descriptor: | Cytoplasmic protein NCK1, SULFATE ION | Authors: | Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. | Deposit date: | 2019-12-13 | Release date: | 2020-02-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
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5QU5
| Domain Swap in the first SH3 domain of human Nck1 | Descriptor: | Cytoplasmic protein NCK1 | Authors: | Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. | Deposit date: | 2019-12-13 | Release date: | 2020-02-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.11 Å) | Cite: | Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
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5QU2
| Crystal Structure of human Nck SH3.1 in complex with peptide PPPVPNPDY | Descriptor: | ACE-PRO-PRO-PRO-VAL-PRO-ASN-PRO-ASP-TYR-NH2, Cytoplasmic protein NCK1, SULFATE ION | Authors: | Rudolph, M.G. | Deposit date: | 2019-12-13 | Release date: | 2020-02-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.04 Å) | Cite: | Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
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5QU7
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5QU4
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5O2Q
| p130Cas SH3 domain Vinculin peptide chimera | Descriptor: | Breast cancer anti-estrogen resistance 1,Vinculin | Authors: | Hexnerova, R, Veverka, V. | Deposit date: | 2017-05-22 | Release date: | 2017-09-20 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners. Sci Rep, 7, 2017
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5O2M
| p130Cas SH3 domain | Descriptor: | Breast cancer anti-estrogen resistance 1 | Authors: | Hexnerova, R, Veverka, V. | Deposit date: | 2017-05-22 | Release date: | 2017-09-20 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners. Sci Rep, 7, 2017
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5QU6
| Crystal Structure of swapped human Nck SH3.1 domain, 1.8A, triclinic | Descriptor: | Cytoplasmic protein NCK1 | Authors: | Rudolph, M.G. | Deposit date: | 2019-12-13 | Release date: | 2020-02-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.816 Å) | Cite: | Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
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1I07
| EPS8 SH3 DOMAIN INTERTWINED DIMER | Descriptor: | EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8 | Authors: | Kishan, K.V.R, Newcomer, M.E. | Deposit date: | 2001-01-29 | Release date: | 2001-05-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain. Protein Sci., 10, 2001
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1I0C
| EPS8 SH3 CLOSED MONOMER | Descriptor: | EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8 | Authors: | Kishan, K.V.R, Newcomer, M.E. | Deposit date: | 2001-01-29 | Release date: | 2001-05-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain. Protein Sci., 10, 2001
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1H92
| SH3 domain of human Lck tyrosine kinase | Descriptor: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK | Authors: | Schweimer, K, Hoffmann, S, Friedrich, U, Biesinger, B, Roesch, P, Sticht, H. | Deposit date: | 2001-02-22 | Release date: | 2001-10-22 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck Biochemistry, 41, 2002
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1H8K
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1JEG
| Solution structure of the SH3 domain from C-terminal Src Kinase complexed with a peptide from the tyrosine phosphatase PEP | Descriptor: | HEMATOPOIETIC CELL PROTEIN-TYROSINE PHOSPHATASE 70Z-PEP, TYROSINE-PROTEIN KINASE CSK | Authors: | Ghose, R, Shekhtman, A, Goger, M.J, Ji, H, Cowburn, D. | Deposit date: | 2001-06-17 | Release date: | 2001-10-31 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | A novel, specific interaction involving the Csk SH3 domain and its natural ligand. Nat.Struct.Biol., 8, 2001
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1K1Z
| Solution structure of N-terminal SH3 domain mutant(P33G) of murine Vav | Descriptor: | vav | Authors: | Ogura, K, Nagata, K, Horiuchi, M, Ebisui, E, Hasuda, T, Yuzawa, S, Nishida, M, Hatanaka, H, Inagaki, F. | Deposit date: | 2001-09-26 | Release date: | 2001-10-10 | Last modified: | 2021-11-10 | Method: | SOLUTION NMR | Cite: | Solution structure of N-terminal SH3 domain of Vav and the recognition site for Grb2 C-terminal SH3 domain J.BIOMOL.NMR, 22, 2002
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1JO8
| Structural analysis of the yeast actin binding protein Abp1 SH3 domain | Descriptor: | ACTIN BINDING PROTEIN, SULFATE ION | Authors: | Fazi, B, Cope, M.J, Douangamath, A, Ferracuti, S, Schirwitz, K, Zucconi, A, Drubin, D.G, Wilmanns, M, Cesareni, G, Castagnoli, L. | Deposit date: | 2001-07-27 | Release date: | 2002-03-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis. J.Biol.Chem., 277, 2002
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1K76
| Solution Structure of the C-terminal Sem-5 SH3 Domain (Minimized Average Structure) | Descriptor: | SEX MUSCLE ABNORMAL PROTEIN 5 | Authors: | Ferreon, J, Volk, D, Luxon, B, Gorenstein, D, Hilser, V. | Deposit date: | 2001-10-18 | Release date: | 2003-05-20 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Solution Structure, Dynamics and Thermodynamics of the Native State Ensemble
of Sem-5 C-Terminal SH3 Domain Biochemistry, 42, 2003
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1IO6
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1KFZ
| Solution Structure of C-terminal Sem-5 SH3 Domain (Ensemble of 16 Structures) | Descriptor: | SEX MUSCLE ABNORMAL PROTEIN 5 | Authors: | Ferreon, J.C, Volk, D.E, Luxon, B.A, Gorenstein, D, Hilser, V.J. | Deposit date: | 2001-11-24 | Release date: | 2003-05-20 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Solution Structure, Dynamics and Thermodynamics of the Native State Ensemble
of Sem-5 C-Terminal SH3 Domain Biochemistry, 42, 2003
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1KIK
| SH3 Domain of Lymphocyte Specific Kinase (LCK) | Descriptor: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK | Authors: | Briese, L, Willbold, D. | Deposit date: | 2001-12-03 | Release date: | 2001-12-12 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Structure determination of human Lck unique and SH3 domains by nuclear magnetic resonance spectroscopy. Bmc Struct.Biol., 3, 2003
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