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2YUQ
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Solution structure of the SH3 domain of human Tyrosine-protein kinase ITK/TSK
Descriptor: Tyrosine-protein kinase ITK/TSK
Authors:Abe, H, Miyamoto, K, Tochio, N, Sato, M, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-06
Release date:2007-10-09
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain of human Tyrosine-protein kinase ITK/TSK
To be Published
6A9C
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BU of 6a9c by Molmil
Crystal Structure c-terminal SH3 domain of Myosin IB from Entamoeba histolytica bound to EhFP10(GEF) peptide.
Descriptor: Peptide from Rho guanine nucleotide exchange factor, SULFATE ION, Unconventional myosin IB
Authors:Gautam, G, Gourinath, S.
Deposit date:2018-07-13
Release date:2019-06-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:EhFP10: A FYVE family GEF interacts with myosin IB to regulate cytoskeletal dynamics during endocytosis in Entamoeba histolytica.
Plos Pathog., 15, 2019
6XVM
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BU of 6xvm by Molmil
Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 2
Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A, Plaza-Garrido, M.
Deposit date:2020-01-22
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XVN
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Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 1
Descriptor: Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A, Plaza-Garrido, M.
Deposit date:2020-01-22
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
3IQL
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BU of 3iql by Molmil
Crystal structure of the rat endophilin-A1 SH3 domain
Descriptor: CHLORIDE ION, Endophilin-A1
Authors:Trempe, J.F, Kozlov, G, Camacho, E.M, Gehring, K.
Deposit date:2009-08-20
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.
Mol.Cell, 36, 2009
6ATV
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BU of 6atv by Molmil
The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions
Descriptor: Adapter molecule crk, proline-rich motif in IAV-NS1
Authors:Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H.
Deposit date:2017-08-29
Release date:2018-08-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Molecular Mechanisms of Tight Binding through Fuzzy Interactions.
Biophys. J., 114, 2018
3I9Q
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BU of 3i9q by Molmil
Crystal Structure of the triple mutant S19G-P20D-R21S of alpha spectrin SH3 domain
Descriptor: SULFATE ION, Spectrin alpha chain
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2009-07-12
Release date:2009-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The effect of a proline residue on the rate of growth and the space group of alpha-spectrin SH3-domain crystals.
Acta Crystallogr.,Sect.D, 65, 2009
2XMF
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BU of 2xmf by Molmil
Myosin 1e SH3
Descriptor: MYOSIN 1E SH3, OCTANE 1,8-DIAMINE
Authors:Edwards, T, Allsop, G, Peckham, M.
Deposit date:2010-07-27
Release date:2011-08-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Myosin 1E SH3
To be Published
6XX3
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Crystal structure of the c-Src SH3 domain H122R-Q128E mutant in complex with Cu(II) at pH 6.5 co-crystallized with methyl beta-cyclodextrin
Descriptor: COPPER (II) ION, Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2020-01-26
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
2YUP
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BU of 2yup by Molmil
Solution structure of the second SH3 domain of human Vinexin
Descriptor: Vinexin
Authors:Abe, H, Tochio, N, Miyamoto, K, Saito, K, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-06
Release date:2007-10-09
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the second SH3 domain of human Vinexin
To be Published
6XVO
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Crystal structure of the intertwined dimer of the c-Src SH3 domain without ATCUN motif
Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
Authors:Camara-Artigas, A, Plaza-Garrido, M.
Deposit date:2020-01-22
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XX4
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BU of 6xx4 by Molmil
Crystal structure of the c-Src SH3 domain H122R-Q128E mutant in complex with Ni(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin
Descriptor: Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2020-01-26
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XX5
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BU of 6xx5 by Molmil
Crystal structure of the c-Src SH3 domain H122R-Q128K mutant in complex with Ni(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin
Descriptor: Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2020-01-26
Release date:2020-05-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XX2
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BU of 6xx2 by Molmil
Crystal structure of the c-Src SH3 domain H122R-Q128K mutant in complex with Cu(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin
Descriptor: COPPER (II) ION, Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2020-01-26
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6C4S
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BU of 6c4s by Molmil
Human cSrc SH3 Domain in complex with Choline Kinase fragment 60-69
Descriptor: Proto-oncogene tyrosine-protein kinase Src,cSrc SH3 Domain, ZINC ION
Authors:Kall, S.L, Lavie, A.
Deposit date:2018-01-12
Release date:2019-01-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase.
Sci Rep, 9, 2019
3H0F
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BU of 3h0f by Molmil
Crystal structure of the human Fyn SH3 R96W mutant
Descriptor: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, Proto-oncogene tyrosine-protein kinase Fyn
Authors:Ponchon, L, Hoh, F, Labesse, G, Dumas, C, Arold, S.T.
Deposit date:2009-04-09
Release date:2010-04-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
3H0I
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BU of 3h0i by Molmil
human Fyn SH3 domain R96I mutant, crystal form II
Descriptor: Proto-oncogene tyrosine-protein kinase Fyn
Authors:Dumas, C, Strub, M.-P, Arold, S.T.
Deposit date:2009-04-09
Release date:2010-04-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
3GBQ
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BU of 3gbq by Molmil
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE
Descriptor: GRB2, SOS-1
Authors:Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
Deposit date:1996-12-23
Release date:1997-09-04
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997
3C0C
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BU of 3c0c by Molmil
X-ray Crystal Structure of the Rat Endophilin A2 SH3 Domain
Descriptor: Endophilin-A2
Authors:Loll, P.J, Swain, E.
Deposit date:2008-01-19
Release date:2008-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the SH3 domain of rat endophilin A2
To be Published
3EG2
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BU of 3eg2 by Molmil
Crystal structure of the N114Q mutant of ABL-SH3 domain
Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2008-09-10
Release date:2009-09-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.
J.Biol.Chem., 285, 2010
5HCK
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BU of 5hck by Molmil
HUMAN HCK SH3 DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: HEMATOPOIETIC CELL KINASE
Authors:Horita, D.A, Baldisseri, D.M, Zhang, W, Altieri, A.S, Smithgall, T.E, Gmeiner, W.H, Byrd, R.A.
Deposit date:1998-03-09
Release date:1998-06-17
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the human Hck SH3 domain and identification of its ligand binding site.
J.Mol.Biol., 278, 1998
3EG0
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BU of 3eg0 by Molmil
Crystal structure of the N114T mutant of ABL-SH3 domain
Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2008-09-10
Release date:2009-09-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.
J.Biol.Chem., 285, 2010
5IHK
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BU of 5ihk by Molmil
Crystal Structure of the alpha spectrin SH3 domain mutant N47A
Descriptor: ACETATE ION, PROLINE, SULFATE ION, ...
Authors:Camara-Artigas, A.
Deposit date:2016-02-29
Release date:2017-03-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal Structure of the alpha spectrin SH3 domain mutant N47A
to be published
3FJ5
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BU of 3fj5 by Molmil
Crystal structure of the c-src-SH3 domain
Descriptor: ACETATE ION, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ...
Authors:Camara-Artigas, A.
Deposit date:2008-12-14
Release date:2009-03-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Intertwined dimeric structure for the SH3 domain of the c-Src tyrosine kinase induced by polyethylene glycol binding
Febs Lett., 583, 2009
5I11
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BU of 5i11 by Molmil
Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain T114S-Q128R mutant
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, ...
Authors:Camara-Artigas, A.
Deposit date:2016-02-05
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain T114S-Q128R mutant
To Be Published

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