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1SHG
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CRYSTAL STRUCTURE OF A SRC-HOMOLOGY 3 (SH3) DOMAIN
Descriptor: ALPHA-SPECTRIN SH3 DOMAIN
Authors:Noble, M, Pauptit, R, Musacchio, A, Saraste, M, Wierenga, R.K.
Deposit date:1993-05-19
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a Src-homology 3 (SH3) domain.
Nature, 359, 1992
1RLQ
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TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS
Descriptor: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND RLP2 (RALPPLPRY)
Authors:Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L.
Deposit date:1994-10-10
Release date:1995-02-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.
Science, 266, 1994
1RUW
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Crystal structure of the SH3 domain from S. cerevisiae Myo3
Descriptor: IMIDAZOLE, Myosin-3 isoform
Authors:Kursula, P, Kursula, I, Lehmann, F, Song, Y.H, Wilmanns, M.
Deposit date:2003-12-12
Release date:2005-03-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the SH3 domain from S. cerevisiae Myo3
To be Published
1TUD
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ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48
Descriptor: ALPHA-SPECTRIN
Authors:Viguera, A.R, Serrano, L, Wilmanns, M.
Deposit date:1996-02-29
Release date:1996-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics.
J.Mol.Biol., 247, 1995
1RLP
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TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS
Descriptor: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND RLP2 (RALPPLPRY)
Authors:Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L.
Deposit date:1994-10-10
Release date:1995-02-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.
Science, 266, 1994
1U06
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crystal structure of chicken alpha-spectrin SH3 domain
Descriptor: AZIDE ION, Spectrin alpha chain, brain
Authors:Chevelkov, V, Faelber, K, Diehl, A, Heinemann, U, Oschkinat, H, Reif, B.
Deposit date:2004-07-13
Release date:2005-01-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Detection of dynamic water molecules in a microcrystalline sample of the SH3 domain of alpha-spectrin by MAS solid-state NMR.
J.Biomol.Nmr, 31, 2005
1U3O
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BU of 1u3o by Molmil
Solution structure of rat Kalirin N-terminal SH3 domain
Descriptor: Huntingtin-associated protein-interacting protein
Authors:Schiller, M.R, Chakrabarti, K, King, G.F, Schiller, N.I, Eipper, B.A, Maciejewski, M.W.
Deposit date:2004-07-22
Release date:2005-07-26
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Regulation of RhoGEF Activity by Intramolecular and Intermolecular SH3 Domain Interactions.
J.Biol.Chem., 281, 2006
1UE9
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Solution structure of the fourth SH3 domain of human intersectin 2 (KIAA1256)
Descriptor: Intersectin 2
Authors:Tochio, N, Kigawa, T, Koshiba, S, Kobayashi, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-09
Release date:2003-11-09
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the fourth SH3 domain of human intersectin 2 (KIAA1256)
To be Published
1TUC
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ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT S19-P20
Descriptor: ALPHA-SPECTRIN
Authors:Wilmanns, M, Serrano, L, Viguera, A.R.
Deposit date:1996-02-29
Release date:1996-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics.
J.Mol.Biol., 247, 1995
1SSH
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BU of 1ssh by Molmil
Crystal structure of the SH3 domain from a S. cerevisiae hypothetical 40.4 kDa protein in complex with a peptide
Descriptor: 12-mer peptide from Cytoskeleton assembly control protein SLA1, Hypothetical 40.4 kDa protein in PES4-HIS2 intergenic region
Authors:Kursula, P, Kursula, I, Lehmann, F, Song, Y.-H, Wilmanns, M.
Deposit date:2004-03-24
Release date:2005-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Yeast SH3 domain structural genomics
To be Published
1UHF
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BU of 1uhf by Molmil
Solution Structure of the third SH3 domain of human intersectin 2(KIAA1256)
Descriptor: INTERSECTIN 2
Authors:Suzuki, S, Hatanaka, H, Koshiba, S, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-07-03
Release date:2004-08-10
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of the third SH3 domain of human intersectin 2(KIAA1256)
To be Published
1UJ0
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BU of 1uj0 by Molmil
Crystal Structure of STAM2 SH3 domain in complex with a UBPY-derived peptide
Descriptor: PHOSPHATE ION, deubiquitinating enzyme UBPY, signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
Authors:Kaneko, T, Kumasaka, T, Ganbe, T, Sato, T, Miyazawa, K, Kitamura, N, Tanaka, N.
Deposit date:2003-07-24
Release date:2003-12-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain.
J.Biol.Chem., 278, 2003
1TG0
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0.97-A structure of the SH3 domain of bbc1
Descriptor: Myosin tail region-interacting protein MTI1
Authors:Kursula, P, Kursula, I, Lehmann, F, Song, Y.H, Wilmanns, M.
Deposit date:2004-05-28
Release date:2005-06-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Saccharomyces cerevisiae SH3 domain structural genomics
To be Published
1VA7
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BU of 1va7 by Molmil
Yeast Myo3 SH3 domain, triclinic crystal form
Descriptor: GLYCEROL, Myosin-3 isoform
Authors:Kursula, P, Lehmann, F, Song, Y.H, Wilmanns, M.
Deposit date:2004-02-12
Release date:2005-06-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:High-throughput structural genomics of yeast SH3 domains
To be Published
1UTI
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BU of 1uti by Molmil
Mona/Gads SH3C in complex with HPK derived peptide
Descriptor: GRB2-RELATED ADAPTOR PROTEIN 2, MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 1
Authors:Lewitzky, M, Harkiolaki, M, Domart, M.C, Feller, S.M.
Deposit date:2003-12-09
Release date:2004-05-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mona/Gads Sh3C Binding to Hematopoietic Progenitor Kinase 1 (Hpk1) Combines an Atypical SH3 Binding Motif, R/Kxxk, with a Classical Pxxp Motif Embedded in a Polyproline Type II (Ppii) Helix
J.Biol.Chem., 279, 2004
1UUE
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a-SPECTRIN SH3 DOMAIN (V44T, D48G MUTANT)
Descriptor: SPECTRIN ALPHA CHAIN
Authors:Vega, M.C, Fernandez, A, Wilmanns, M, Serrano, L.
Deposit date:2003-12-18
Release date:2004-02-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Solvation in Protein Folding Analysis: Combination of Theoretical and Experimental Approaches
Proc.Natl.Acad.Sci.USA, 101, 2004
1SRM
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BU of 1srm by Molmil
1H AND 15N ASSIGNMENTS AND SECONDARY STRUCTURE OF THE SRC SH3 DOMAIN
Descriptor: SRC TYROSINE KINASE SH3 DOMAIN
Authors:Yu, H, Rosen, M.K, Shin, T.B, Seidel-Dugan, C, Brugge, J.S, Schreiber, S.L.
Deposit date:1994-03-07
Release date:1994-05-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:1H and 15N assignments and secondary structure of the Src SH3 domain.
FEBS Lett., 324, 1993
1SHF
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BU of 1shf by Molmil
CRYSTAL STRUCTURE OF THE SH3 DOMAIN IN HUMAN FYN; COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF SH3 DOMAINS IN TYROSINE KINASES AND SPECTRIN
Descriptor: FYN TYROSINE KINASE SH3 DOMAIN
Authors:Noble, M, Musacchio, A, Saraste, M, Wierenga, R.
Deposit date:1993-05-19
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the SH3 domain in human Fyn; comparison of the three-dimensional structures of SH3 domains in tyrosine kinases and spectrin.
EMBO J., 12, 1993
1M3A
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BU of 1m3a by Molmil
Solution structure of a circular form of the truncated N-terminal SH3 domain from oncogene protein c-Crk.
Descriptor: Proto-oncogene C-crk
Authors:Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D.
Deposit date:2002-06-27
Release date:2003-08-05
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
To be Published
1M8M
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BU of 1m8m by Molmil
SOLID-STATE MAS NMR STRUCTURE OF THE A-SPECTRIN SH3 DOMAIN
Descriptor: SPECTRIN ALPHA CHAIN, BRAIN
Authors:Castellani, F, Van Rossum, B, Diehl, A, Schubert, M, Rehbein, K, Oschkinat, H.
Deposit date:2002-07-25
Release date:2002-11-20
Last modified:2022-12-21
Method:SOLID-STATE NMR
Cite:Structure of a protein determined by solid-state magic-angle-spinning NMR spectroscopy
Nature, 420, 2002
2GQI
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BU of 2gqi by Molmil
Solution structure of the SH3 domain of human Ras GTPase-activating protein 1
Descriptor: Ras GTPase-activating protein 1
Authors:Kurosaki, C, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-21
Release date:2006-10-21
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain of human Ras GTPase-activating protein 1
To be Published
2IIM
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BU of 2iim by Molmil
SH3 Domain of Human Lck
Descriptor: CALCIUM ION, Proto-oncogene tyrosine-protein kinase LCK, TETRAETHYLENE GLYCOL, ...
Authors:Romir, J, Egerer-Sieber, C, Muller, Y.A.
Deposit date:2006-09-28
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1 Å)
Cite:Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs.
J.Mol.Biol., 365, 2007
1M30
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BU of 1m30 by Molmil
Solution structure of N-terminal SH3 domain from oncogene protein c-Crk
Descriptor: Proto-oncogene C-crk
Authors:Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D.
Deposit date:2002-06-26
Release date:2003-08-05
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
To be Published
1M3C
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BU of 1m3c by Molmil
Solution structure of a circular form of the N-terminal SH3 domain (E132C, E133G, R191G mutant) from oncogene protein c-Crk
Descriptor: Proto-oncogene C-crk
Authors:Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D.
Deposit date:2002-06-27
Release date:2003-08-05
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain
To be Published
2J05
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Crystal structure of the RasGAP SH3 domain at 1.5 Angstrom resolution
Descriptor: RAS GTPASE-ACTIVATING PROTEIN 1
Authors:Ross, B, Gajhede, M, Kristensen, O.
Deposit date:2006-08-01
Release date:2007-01-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High Resolution Crystal Structures of the P120 Rasgap SH3 Domain.
Biochem.Biophys.Res.Commun., 353, 2007

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