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4ZNX
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BU of 4znx by Molmil
Crystal structure of the Fyn-SH3 domain in complex with the high affinity peptide APP12
Descriptor: APP12, Tyrosine-protein kinase Fyn
Authors:Camara-Artigas, A.
Deposit date:2015-05-05
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase.
Acta Crystallogr.,Sect.F, 72, 2016
5VEI
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BU of 5vei by Molmil
Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
Descriptor: Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION
Authors:Liu, Y, Tempel, W, Huang, H, Gu, J, Liu, K, Sidhu, S.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2017-04-04
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
To be Published
3CQT
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BU of 3cqt by Molmil
N53I V55L MUTANT of FYN SH3 DOMAIN
Descriptor: Proto-oncogene tyrosine-protein kinase Fyn
Authors:Neculai, A.M, Zarrine-Afsar, A, Howell, P.L, Davidson, A, Chan, H.S.
Deposit date:2008-04-03
Release date:2008-07-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
8KDX
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BU of 8kdx by Molmil
Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current
Descriptor: Microtubule-associated protein tau, Tyrosine-protein kinase Fyn
Authors:Padavattan, S, Jos, S.
Deposit date:2023-08-10
Release date:2024-02-28
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current.
J.Mol.Biol., 436, 2024
4OMO
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BU of 4omo by Molmil
Crystal structure of the c-Src tyrosine kinase SH3 domain mutant Q128E
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2014-01-27
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
7JT9
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BU of 7jt9 by Molmil
Fgr SH3 domain crystal structure
Descriptor: Tyrosine-protein kinase Fgr
Authors:Perez, I, Berndt, S, Gurevich, V.V, Iverson, T.M.
Deposit date:2020-08-17
Release date:2022-01-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr.
J.Mol.Biol., 434, 2022
5UL6
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BU of 5ul6 by Molmil
The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions
Descriptor: Adapter molecule crk, Proline-rich motif of nonstructural protein 1 of influenza a virus
Authors:Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H.
Deposit date:2017-01-24
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus.
ACS Chem. Biol., 12, 2017
6NMW
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BU of 6nmw by Molmil
Crystal structure of the human Lyn SH3 domain
Descriptor: Tyrosine-protein kinase Lyn
Authors:Berndt, S, Gurevich, V.V, Iverson, T.M.
Deposit date:2019-01-12
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:Crystal structure of the SH3 domain of human Lyn non-receptor tyrosine kinase.
PLoS ONE, 14, 2019
4RTW
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BU of 4rtw by Molmil
Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12
Descriptor: APP12 peptide, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ...
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2014-11-16
Release date:2015-10-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12
To be Published
6IPY
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BU of 6ipy by Molmil
His-tagged Fyn SH3 domain R96I mutant
Descriptor: Tyrosine-protein kinase Fyn
Authors:Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.343 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
6IPZ
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BU of 6ipz by Molmil
Fyn SH3 domain R96W mutant, crystallized with 18-crown-6
Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Tyrosine-protein kinase Fyn
Authors:Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
4Y92
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BU of 4y92 by Molmil
Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain E97T-Q128R mutant
Descriptor: GLYCEROL, Protein-tyrosine kinase, SULFATE ION, ...
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2015-02-16
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain E97T-Q128R mutant
to be published
8WFF
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BU of 8wff by Molmil
The Crystal Structure of LYN from Biortus.
Descriptor: CHLORIDE ION, CITRATE ANION, Tyrosine-protein kinase Lyn
Authors:Wang, F, Cheng, W, Yuan, Z, Qi, J, Lu, Y.
Deposit date:2023-09-19
Release date:2023-11-22
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The Crystal Structure of LYN from Biortus.
To Be Published
5XGG
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BU of 5xgg by Molmil
Crystal Structure C-terminal SH3 domain of Myosin IB from Entamoeba histolytica
Descriptor: SULFATE ION, Unconventional myosin IB
Authors:Gautam, G, Gourinath, S.
Deposit date:2017-04-13
Release date:2017-08-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition
Acta Crystallogr D Struct Biol, 73, 2017
4ESR
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BU of 4esr by Molmil
Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors
Descriptor: DI(HYDROXYETHYL)ETHER, Jouberin
Authors:Van Petegem, X.F, Liu, P.X, Lobo, P, Jiang, X.
Deposit date:2012-04-23
Release date:2012-06-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL(+) chronic myeloid leukemia cells to tyrosine kinase inhibitors.
Proteomics, 12, 2012
4F16
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BU of 4f16 by Molmil
Crystal Structure of the alpha spectrin SH3 domain at pH 5
Descriptor: Spectrin alpha chain, brain
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2012-05-06
Release date:2013-05-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal Structure of the alpha spectrin SH3 domain at pH 5
To be Published
4F17
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BU of 4f17 by Molmil
Crystal Structure of the alpha spectrin SH3 domain at pH 9
Descriptor: Spectrin alpha chain, brain
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2012-05-06
Release date:2013-05-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structure of the alpha spectrin SH3 domain at pH 9
To be Published
7S4R
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BU of 7s4r by Molmil
Serial Macromolecular Crystallography at ALBA Synchrotron Light Source - alpha Spectrin-SH3 domain
Descriptor: Spectrin alpha chain, non-erythrocytic 1
Authors:Martin-Garcia, J.M, Botha, S, Hu, H, Jernigan, R, Castellvi, A, Lisova, S, Gil, F, Calisto, B, Crespo, I, Roy-Chowdbury, S, Grieco, A, Ketawala, G, Weierstall, U, Spence, J, Fromme, P, Zatsepin, N, Boer, R, Carpena, X.
Deposit date:2021-09-09
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Serial macromolecular crystallography at ALBA Synchrotron Light Source.
J.Synchrotron Radiat., 29, 2022
6EDF
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BU of 6edf by Molmil
Fragment of a tyrosine-protein kinase
Descriptor: FYN, GLYCEROL, UNKNOWN ATOM OR ION
Authors:Tempel, W, Huang, H, Sochirca, I, Liu, K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Sidhu, S.S, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-08-09
Release date:2018-08-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Fragment of a tyrosine-protein kinase
To be Published
6SCW
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BU of 6scw by Molmil
SH3-subunit of chicken alpha spectrin solved by NMR
Descriptor: Spectrin alpha chain, non-erythrocytic 1 isoform X11
Authors:Grohe, K, Hebrank, C, Linser, R.
Deposit date:2019-07-25
Release date:2020-08-12
Last modified:2024-01-31
Method:SOLUTION NMR
Cite:Protein Motional Details Revealed by Complementary Structural Biology Techniques.
Structure, 28, 2020
6SDF
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BU of 6sdf by Molmil
N-terminal SH3 domain of Grb2 protein
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Growth factor receptor-bound protein 2
Authors:Bolgov, A.A, Korban, S.A, Luzik, D.A, Rogacheva, O.N, Zhemkov, V.A, Kim, M, Skrynnikov, N.R, Bezprozvanny, I.B.
Deposit date:2019-07-26
Release date:2020-01-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the SH3 domain of growth factor receptor-bound protein 2.
Acta Crystallogr.,Sect.F, 76, 2020
5XG9
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BU of 5xg9 by Molmil
Crystal Structure of PEG-bound SH3 domain of Myosin IB from Entamoeba histolytica
Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, PENTAETHYLENE GLYCOL, ...
Authors:Gautam, G, Gourinath, S.
Deposit date:2017-04-13
Release date:2017-08-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition
Acta Crystallogr D Struct Biol, 73, 2017
6RO9
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BU of 6ro9 by Molmil
Human spectrin SH3 domain D48G, E7V, K60V
Descriptor: Spectrin alpha, non-erythrocytic 1
Authors:Reverter, D, Navarro, S, Ventura, S.
Deposit date:2019-05-10
Release date:2020-06-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.814 Å)
Cite:Human spectrin SH3 domain D48G, E7V, K60V
To Be Published
3THK
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BU of 3thk by Molmil
Structure of SH3 chimera with a type II ligand linked to the chain C-terminal
Descriptor: BETA-MERCAPTOETHANOL, Proline-rich peptide, SULFATE ION, ...
Authors:Gabdulkhakov, A.G, Gushchina, L.V, Nikulin, A.D, Nikonov, S.V, Filimonov, V.V.
Deposit date:2011-08-19
Release date:2011-11-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:High-Resolution Crystal Structure of Spectrin SH3 Domain Fused with a Proline-Rich Peptide.
J.Biomol.Struct.Dyn., 29, 2011
3UA6
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BU of 3ua6 by Molmil
Crystal Structure of the Human Fyn SH3 domain
Descriptor: FORMIC ACID, GLYCEROL, SODIUM ION, ...
Authors:Camara-Artigas, A, Martin-Garcia, J.M.
Deposit date:2011-10-21
Release date:2012-07-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A protein.
Acta Crystallogr.,Sect.D, 68, 2012

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