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4JUS
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BU of 4jus by Molmil
Crystal structure of a fragment of Human HSPB6
Descriptor: GLYCEROL, Heat shock protein beta-6
Authors:Weeks, S.D, Baranova, E.V, Beelen, S, Heirbaut, M, Gusev, N.B, Strelkov, S.V.
Deposit date:2013-03-25
Release date:2014-02-05
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular structure and dynamics of the dimeric human small heat shock protein HSPB6.
J.Struct.Biol., 185, 2014
4YLB
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BU of 4ylb by Molmil
Crystal Structure of A102D mutant of hsp14.1 from Sulfolobus solfatataricus P2
Descriptor: CHLORIDE ION, Heat shock protein Hsp20
Authors:Liu, L, Chen, J.Y, Yun, C.H.
Deposit date:2015-03-05
Release date:2015-11-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Active-State Structures of a Small Heat-Shock Protein Revealed a Molecular Switch for Chaperone Function
Structure, 23, 2015
3VQM
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BU of 3vqm by Molmil
Small heat shock protein hsp14.0 of C-terminal deletion variant with C-terminal peptide
Descriptor: C-terminal peptide from Small heat shock protein StHsp14.0, Small heat shock protein StHsp14.0
Authors:Hanazono, Y, Takeda, K, Miki, K.
Deposit date:2012-03-26
Release date:2012-06-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural studies on the oligomeric transition of a small heat shock protein, StHsp14.0
J.Mol.Biol., 422, 2012
4MJH
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BU of 4mjh by Molmil
Human Hsp27 core domain in complex with C-terminal peptide
Descriptor: Heat shock protein beta-1
Authors:Laganowsky, A, Cascio, D, Sawaya, M.R, Eisenberg, D.
Deposit date:2013-09-03
Release date:2014-04-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.599 Å)
Cite:The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Proc.Natl.Acad.Sci.USA, 111, 2014
5LUM
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BU of 5lum by Molmil
Alpha-crystallin domain of human HSPB6 patched with its N-terminal peptide
Descriptor: Heat shock protein beta-6, SULFATE ION
Authors:Sluchanko, N.N, Beelen, S, Kulikova, A.A, Weeks, S.D, Antson, A.A, Gusev, N.B, Strelkov, S.V.
Deposit date:2016-09-09
Release date:2017-02-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator.
Structure, 25, 2017
5DS1
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BU of 5ds1 by Molmil
Core domain of the class II small heat-shock protein HSP 17.7 from Pisum sativum
Descriptor: 17.1 kDa class II heat shock protein
Authors:Hochberg, G.K.A, Laganoswky, A, Allison, T.A, Shepherd, D.A, Benesch, J.L.P.
Deposit date:2015-09-16
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions.
Science, 359, 2018
2WJ7
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BU of 2wj7 by Molmil
human alphaB crystallin
Descriptor: ALPHA-CRYSTALLIN B CHAIN
Authors:Naylor, C.E, Bagneris, C, Bateman, O.A, Cronin, N, Keep, N.H, Slingsby, C.
Deposit date:2009-05-22
Release date:2009-08-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.631 Å)
Cite:Crystal Structures of Alpha-Crystallin Domain Dimers of Alphab-Crystallin and Hsp20.
J.Mol.Biol., 392, 2009
4RZK
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BU of 4rzk by Molmil
Crystal structure of Sulfolobus solfataricus Hsp20.1 ACD
Descriptor: Small heat shock protein hsp20 family
Authors:Liang, L, Yun, C.H.
Deposit date:2014-12-22
Release date:2015-12-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.677 Å)
Cite:Crystal structure and function of an unusual dimeric Hsp20.1 provide insight into the thermal protection mechanism of small heat shock proteins.
Biochem.Biophys.Res.Commun., 2015
1GME
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BU of 1gme by Molmil
Crystal structure and assembly of an eukaryotic small heat shock protein
Descriptor: HEAT SHOCK PROTEIN 16.9B
Authors:Van Montfort, R.L.M, Basha, E, Friedrich, K.L, Slingsby, C, Vierling, E.
Deposit date:2001-09-13
Release date:2001-11-29
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure and Assembly of an Eukaryotic Small Heat Shock Protein
Nat.Struct.Biol., 8, 2001
4ELD
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BU of 4eld by Molmil
Crystal Structure of an Activated Variant of Small Heat Shock Protein Hsp16.5
Descriptor: Small heat shock protein HSP16.5
Authors:Spiller, B.W, Mchaourab, H.S, Lin, Y.-L.
Deposit date:2012-04-10
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Crystal structure of an activated variant of small heat shock protein hsp16.5.
Biochemistry, 51, 2012
5ZS6
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BU of 5zs6 by Molmil
Dodecameric structure of a small Heat Shock Protein from Mycobacterium marinum M: Form-2
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLY-ARG-LEU-LEU, ...
Authors:Bhandari, S, Suguna, K.
Deposit date:2018-04-28
Release date:2019-01-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.81191349 Å)
Cite:Dodecameric structure of a small heat shock protein from Mycobacterium marinum M.
Proteins, 87, 2019
4I88
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BU of 4i88 by Molmil
R107G HSP16.5
Descriptor: Small heat shock protein HSP16.5
Authors:Pohl, E, Williamson, I.R, Quinlan, R.A.
Deposit date:2012-12-03
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Changes in the quaternary structure and function of MjHSP16.5 attributable to deletion of the IXI motif and introduction of the substitution, R107G, in the alpha-crystallin domain.
PHILOS.TRANS.R.SOC.LOND.B BIOL.SCI., 368, 2013
1SHS
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BU of 1shs by Molmil
SMALL HEAT SHOCK PROTEIN FROM METHANOCOCCUS JANNASCHII
Descriptor: SMALL HEAT SHOCK PROTEIN
Authors:Kim, K.K, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
Deposit date:1998-07-30
Release date:1999-07-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a small heat-shock protein.
Nature, 394, 1998
5J7N
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BU of 5j7n by Molmil
Crystal structure of a small heat-shock protein from Xylella fastidiosa reveals a distinct high order structure
Descriptor: Low molecular weight heat shock protein
Authors:Fonseca, E.M.B, Scorsato, V, dos Santos, C.A, Tomazini Jr, A, Aparicio, R, Polikarpov, I.
Deposit date:2016-04-06
Release date:2017-04-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a small heat-shock protein from Xylella fastidiosa reveals a distinct high-order structure.
Acta Crystallogr F Struct Biol Commun, 73, 2017
4YLC
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BU of 4ylc by Molmil
Crystal Structure of Del-C4 mutant of hsp14.1 from Sulfolobus solfatataricus P2
Descriptor: CHLORIDE ION, Heat shock protein Hsp20
Authors:Liu, L, Chen, J.Y, Yun, C.H.
Deposit date:2015-03-05
Release date:2015-11-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Active-State Structures of a Small Heat-Shock Protein Revealed a Molecular Switch for Chaperone Function
Structure, 23, 2015
6L6M
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BU of 6l6m by Molmil
HSP18.5 from E. histolytica
Descriptor: Heat shock protein hsp20 family putative
Authors:Kurre, D, Suguna, K.
Deposit date:2019-10-29
Release date:2020-11-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.28000379 Å)
Cite:Network of Entamoeba histolytica HSP18.5 dimers formed by two overlapping [IV]-X-[IV] motifs.
Proteins, 2021
3L1G
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BU of 3l1g by Molmil
Human AlphaB crystallin
Descriptor: Alpha-crystallin B chain, SULFATE ION
Authors:Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D.
Deposit date:2009-12-11
Release date:2010-05-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function.
Protein Sci., 19, 2010
6DV5
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BU of 6dv5 by Molmil
Oligomeric complex of a Hsp27 24-mer at 3.6 A resolution
Descriptor: Heat shock protein beta-1
Authors:Aguda, A.H, Brayer, G.D.
Deposit date:2018-06-22
Release date:2019-06-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Structure-Guided Discovery of Ivermectin as an Inhibitor of Heat Shock Protein-27 Phosphorylation and Depolymerization.
To Be Published
4YDZ
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BU of 4ydz by Molmil
Stress-induced protein 1 from Caenorhabditis elegans
Descriptor: Stress-induced protein 1
Authors:Fleckenstein, T, Kastenmueller, A, Stein, M.L, Peters, C, Daake, M, Krause, M, Weinfurtner, D, Haslbeck, M, Weinkauf, S, Groll, M, Buchner, J.
Deposit date:2015-02-23
Release date:2015-06-10
Last modified:2015-07-01
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pH-Dependent Conformational Changes.
Mol.Cell, 58, 2015
7BZY
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BU of 7bzy by Molmil
Hsp21-DXPS
Descriptor: 1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic, Heat shock protein 21
Authors:Lau, W.C.Y.
Deposit date:2020-04-29
Release date:2021-07-28
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of substrate recognition and thermal protection by a small heat shock protein.
Nat Commun, 12, 2021
2Y22
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BU of 2y22 by Molmil
Human AlphaB-crystallin Domain (residues 67-157)
Descriptor: ALPHA-CRYSTALLIN B
Authors:Naylor, C.E, Bagneris, C, Clark, A.R, Keep, N.H, Slingsby, C.
Deposit date:2010-12-13
Release date:2011-03-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal Structure of R120G Disease Mutant of Human Alphab-Crystallin Domain Dimer Shows Closure of a Groove
J.Mol.Biol., 408, 2011
5ZUL
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BU of 5zul by Molmil
Small heat shock protein from Mycobacterium marinum M : Form-3
Descriptor: Small heat shock protein
Authors:Bhandari, S, Suguna, K.
Deposit date:2018-05-08
Release date:2019-01-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Dodecameric structure of a small heat shock protein from Mycobacterium marinum M.
Proteins, 87, 2019
6F2R
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BU of 6f2r by Molmil
A heterotetramer of human HspB2 and HspB3
Descriptor: Heat shock protein beta-2, Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-2, HspB2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2, ...
Authors:Clark, A.R, Cole, A.R, Boelens, W.C, Keep, N.H, Slingsby, C.
Deposit date:2017-11-27
Release date:2018-07-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3.
J.Mol.Biol., 430, 2018
4ZJA
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BU of 4zja by Molmil
Small heat shock protein AgsA from Salmonella typhimurium: C-terminal truncated construct
Descriptor: Aggregation suppressing protein
Authors:Mani, N, Suguna, K.
Deposit date:2015-04-29
Release date:2016-04-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (4.101 Å)
Cite:Multiple oligomeric structures of a bacterial small heat shock protein
Sci Rep, 6, 2016
5LTW
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BU of 5ltw by Molmil
Complex of human 14-3-3 sigma CLU1 mutant with phosphorylated heat shock protein B6
Descriptor: 14-3-3 protein sigma, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Heat shock protein beta-6, ...
Authors:Sluchanko, N.N, Beelen, S, Kulikova, A.A, Weeks, S.D, Antson, A.A, Gusev, N.B, Strelkov, S.V.
Deposit date:2016-09-07
Release date:2017-02-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator.
Structure, 25, 2017

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