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8FS5
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BU of 8fs5 by Molmil
Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 3 (open 9-1-1 and stably bound chamber DNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2023-01-09
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology.
Biorxiv, 2023
8FS4
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BU of 8fs4 by Molmil
Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 2 (open 9-1-1 ring and flexibly bound chamber DNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2023-01-09
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology.
Biorxiv, 2023
8FS6
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BU of 8fs6 by Molmil
Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 4 (partially closed 9-1-1 and stably bound chamber DNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2023-01-09
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology.
Biorxiv, 2023
8GLV
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BU of 8glv by Molmil
96-nm repeat unit of doublet microtubules from Chlamydomonas reinhardtii flagella
Descriptor: 28 kDa inner dynein arm light chain, axonemal, AAA+ ATPase domain-containing protein, ...
Authors:Walton, T, Brown, A.
Deposit date:2023-03-23
Release date:2023-05-31
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023
7OAT
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BU of 7oat by Molmil
Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Petrovic, S, Heinemann, U, Roske, Y.
Deposit date:2021-04-20
Release date:2022-08-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.995 Å)
Cite:Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.
Proc.Natl.Acad.Sci.USA, 120, 2023
8H3H
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BU of 8h3h by Molmil
Human ATAD2 Walker B mutant, ATP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase family AAA domain-containing protein 2
Authors:Cho, C, Song, J.
Deposit date:2022-10-08
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
Commun Biol, 6, 2023
7P0M
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BU of 7p0m by Molmil
Human mitochondrial Lon protease with substrate in the ATPase and protease domains
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
Authors:Valentin Gese, G, Shahzad, S, Hallberg, B.M.
Deposit date:2021-06-30
Release date:2021-08-11
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:A dual allosteric pathway drives human mitochondrial Lon
To Be Published
7P09
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BU of 7p09 by Molmil
Human mitochondrial Lon protease with substrate in the ATPase domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
Authors:Valentin Gese, G, Shahzad, S, Hallberg, B.M.
Deposit date:2021-06-29
Release date:2021-08-11
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A dual allosteric pathway drives human mitochondrial Lon
To Be Published
7P0B
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BU of 7p0b by Molmil
Human mitochondrial Lon protease without substrate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Valentin Gese, G, Shahzad, S, Hallberg, B.M.
Deposit date:2021-06-29
Release date:2021-08-11
Method:ELECTRON MICROSCOPY (4 Å)
Cite:A dual allosteric pathway drives human mitochondrial Lon
To Be Published
7P6U
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BU of 7p6u by Molmil
Lon protease from Thermus Thermophilus
Descriptor: (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK), Lon protease, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Coscia, F, Lowe, J.
Deposit date:2021-07-18
Release date:2021-10-27
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of the full-length Lon protease from Thermus thermophilus.
Febs Lett., 595, 2021
7OXO
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BU of 7oxo by Molmil
human LonP1, R-state, incubated in AMPPCP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Abrahams, J.P, Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T.
Deposit date:2021-06-22
Release date:2021-12-22
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
8HL7
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BU of 8hl7 by Molmil
Crystal structure of p97 N/D1 in complex with a valosin-containing protein methyltransferase
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Kang, W, Yang, J.K.
Deposit date:2022-11-29
Release date:2023-07-12
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for recognition and methylation of p97 by METTL21D, a valosin-containing protein lysine methyltransferase.
Iscience, 26, 2023
8HRZ
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BU of 8hrz by Molmil
Crystal structure of the p97-N/D1 hexamer in complex with six p47-UBX domains
Descriptor: ADENOSINE-5'-DIPHOSPHATE, NSFL1 cofactor p47, Transitional endoplasmic reticulum ATPase
Authors:Nguyen, T.Q, Kang, W.
Deposit date:2022-12-16
Release date:2023-12-20
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the p97-N/D1 hexmaer in complex with six p47-UBX domains
J. Korean Chem. Soc., 68, 2024
7PXA
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BU of 7pxa by Molmil
Open-gate mycobacterium 20S CP proteasome in complex MPA - global 3D refinement
Descriptor: AAA ATPase forming ring-shaped complexes, Proteasome subunit alpha, Proteasome subunit beta
Authors:Jomaa, A, Kavalchuk, M, Weber-Ban, E.
Deposit date:2021-10-08
Release date:2022-01-19
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
Nat Commun, 13, 2022
7PXB
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BU of 7pxb by Molmil
Substrate-engaged mycobacterial Proteasome-associated ATPase - focused 3D refinement (state B)
Descriptor: AAA ATPase forming ring-shaped complexes, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Jomaa, A, Kavalchuk, M, Weber-Ban, E.
Deposit date:2021-10-08
Release date:2022-01-19
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
Nat Commun, 13, 2022
7PXC
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BU of 7pxc by Molmil
Substrate-engaged mycobacterial Proteasome-associated ATPase in complex with open-gate 20S CP - composite map (state A)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Jomaa, A, Kavalchuk, M, Weber-Ban, E.
Deposit date:2021-10-08
Release date:2022-01-19
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
Nat Commun, 13, 2022
7PX9
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BU of 7px9 by Molmil
Substrate-engaged mycobacterial Proteasome-associated ATPase - focused 3D refinement (state A)
Descriptor: AAA ATPase forming ring-shaped complexes, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Jomaa, A, Kavalchuk, M, Weber-Ban, E.
Deposit date:2021-10-08
Release date:2022-01-19
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
Nat Commun, 13, 2022
7PXD
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BU of 7pxd by Molmil
Substrate-engaged mycobacterial Proteasome-associated ATPase in complex with open-gate 20S CP - composite map (state B)
Descriptor: AAA ATPase forming ring-shaped complexes, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Jomaa, A, Kavalchuk, M, Weber-Ban, E.
Deposit date:2021-10-08
Release date:2022-01-19
Last modified:2022-01-26
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
Nat Commun, 13, 2022
8J07
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BU of 8j07 by Molmil
96nm repeat of human respiratory doublet microtubule and associated axonemal complexes
Descriptor: ACTA2, Axonemal dynein light intermediate polypeptide 1, Calaxin, ...
Authors:Gui, M, Brown, A.
Deposit date:2023-04-09
Release date:2023-07-26
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023
8K3Y
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BU of 8k3y by Molmil
The "5+1" heteromeric structure of Lon protease consisting of a spiral pentamer with Y224S mutation and an N-terminal-truncated monomeric E613K mutant
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease
Authors:Li, S, Hsieh, K.Y, Kuo, C.I, Zhang, K, Chang, C.I.
Deposit date:2023-07-17
Release date:2023-10-25
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (4.42 Å)
Cite:A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
8JUY
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BU of 8juy by Molmil
Human ATAD2 Walker B mutant-H3/H4K5Q complex, ATP state (Class II)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase family AAA domain-containing protein 2
Authors:Cho, C, Song, J.
Deposit date:2023-06-27
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (4.34 Å)
Cite:Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
Commun Biol, 6, 2023
8JUZ
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BU of 8juz by Molmil
Human ATAD2 Walker B mutant-H3/H4K5Q complex, ATP state (Class III)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase family AAA domain-containing protein 2
Authors:Cho, C, Song, J.
Deposit date:2023-06-27
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (4.29 Å)
Cite:Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
Commun Biol, 6, 2023
8JUW
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BU of 8juw by Molmil
Human ATAD2 Walker B mutant-H3/H4K5Q complex, ATP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase family AAA domain-containing protein 2
Authors:Cho, C, Song, J.
Deposit date:2023-06-27
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
Commun Biol, 6, 2023
8OOI
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BU of 8ooi by Molmil
Full composite cryo-EM map of p97/VCP in ADP.Pi state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Cheng, T.C, Sakata, E, Schuetz, A.K.
Deposit date:2023-04-05
Release date:2024-01-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Characterizing ATP processing by the AAA+ protein p97 at the atomic level.
Nat.Chem., 16, 2024
8OKA
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BU of 8oka by Molmil
Human Mitochondrial Lon Y394F Mutant ADP Bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
Deposit date:2023-03-28
Release date:2024-04-10
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024

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數據於2024-05-29公開中

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