6PXL
| 3.74 Angstroms resolution structure of HlsU with an axial-channel plug | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, MAGNESIUM ION, ... | Authors: | Baytshtok, V, Grant, R.A, Sauer, R.T. | Deposit date: | 2019-07-26 | Release date: | 2020-07-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.741 Å) | Cite: | Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug. Cell Rep, 34, 2021
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6PXK
| 3.65 Angstroms resolution structure of HslU with an axial-channel plug | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, SULFATE ION, ... | Authors: | Baytshtok, V, Grant, R.A, Sauer, R.T. | Deposit date: | 2019-07-26 | Release date: | 2020-07-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.647 Å) | Cite: | Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug. Cell Rep, 34, 2021
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5OG1
| Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state | Descriptor: | Chaperone protein ClpB,ATP-dependent Clp protease ATP-binding subunit ClpA,Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Deville, C, Carroni, M, Franke, K.B, Topf, M, Bukau, B, Mogk, A, Saibil, H.R. | Deposit date: | 2017-07-11 | Release date: | 2017-08-16 | Last modified: | 2019-08-21 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase. Sci Adv, 3, 2017
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5OFO
| Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state, bound to the model substrate casein | Descriptor: | Chaperone protein ClpB,ATP-dependent Clp protease ATP-binding subunit ClpA,Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Deville, C, Carroni, M, Franke, K.B, Topf, M, Bukau, B, Mogk, A, Saibil, H.R. | Deposit date: | 2017-07-11 | Release date: | 2017-08-16 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase. Sci Adv, 3, 2017
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1YYF
| Correction of X-ray Intensities from an HslV-HslU co-crystal containing lattice translocation defects | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent hsl protease ATP-binding subunit hslU, ATP-dependent protease hslV | Authors: | Wang, J, Rho, S.H, Park, H.H, Eom, S.H. | Deposit date: | 2005-02-24 | Release date: | 2005-07-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (4.16 Å) | Cite: | Correction of X-ray intensities from an HslV-HslU co-crystal containing lattice-translocation defects. Acta Crystallogr.,Sect.D, 61, 2005
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1XWI
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6CHS
| Cdc48-Npl4 complex in the presence of ATP-gamma-S | Descriptor: | MAGNESIUM ION, Npl4, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Kim, K.H, Bodnar, N.O, Walz, T, Rapoport, T.A. | Deposit date: | 2018-02-22 | Release date: | 2018-07-04 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4. Nat. Struct. Mol. Biol., 25, 2018
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6DJV
| Mtb ClpB in complex with ATPgammaS and casein, Conformer 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Yu, H.J, Li, H.L. | Deposit date: | 2018-05-26 | Release date: | 2018-09-26 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | ATP hydrolysis-coupled peptide translocation mechanism ofMycobacterium tuberculosisClpB. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6DJU
| Mtb ClpB in complex with ATPgammaS and casein, Conformer 1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Yu, H.J, Li, H.L. | Deposit date: | 2018-05-26 | Release date: | 2018-09-26 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | ATP hydrolysis-coupled peptide translocation mechanism ofMycobacterium tuberculosisClpB. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1OFI
| Asymmetric complex between HslV and I-domain deleted HslU (H. influenzae) | Descriptor: | 4-IODO-3-NITROPHENYL ACETYL-LEUCINYL-LEUCINYL-LEUCINYL-VINYLSULFONE, ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ... | Authors: | Kwon, A.R, Kessler, B.M, Overkleeft, H.S, McKay, D.B. | Deposit date: | 2003-04-14 | Release date: | 2003-07-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and Reactivity of an Asymmetric Complex between Hslv and I-Domain Deleted Hslu, a Prokaryotic Homolog of the Eukaryotic Proteasome J.Mol.Biol., 330, 2003
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1OFH
| Asymmetric complex between HslV and I-domain deleted HslU (H. influenzae) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV, ... | Authors: | Kwon, A.R, Kessler, B.M, Overkleeft, H.S, McKay, D.B. | Deposit date: | 2003-04-14 | Release date: | 2003-07-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure and Reactivity of an Asymmetric Complex between Hslv and I-Domain Deleted Hslu, a Prokaryotic Homolog of the Eukaryotic Proteasome J.Mol.Biol., 330, 2003
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7BPB
| Human AAA+ ATPase VCP mutant - T76E, AMP-PNP bound form, Conformation I | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | Authors: | Yang, C, Zhang, H. | Deposit date: | 2020-03-22 | Release date: | 2021-03-31 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
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7BP9
| Human AAA+ ATPase VCP mutant - T76E, ADP-bound form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | Authors: | Yang, C, Zhang, H. | Deposit date: | 2020-03-21 | Release date: | 2021-03-31 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
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7BP8
| Human AAA+ ATPase VCP mutant - T76A, ADP-bound form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | Authors: | Yang, C, Zhang, H. | Deposit date: | 2020-03-21 | Release date: | 2021-03-31 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
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7BPA
| Human AAA+ ATPase VCP mutant - T76A, AMP-PNP-bound form, Conformation I | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | Authors: | Yang, C, Zhang, H. | Deposit date: | 2020-03-21 | Release date: | 2021-03-31 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle. Cell Death Differ., 2022
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2ZAM
| Crystal structure of mouse SKD1/VPS4B apo-form | Descriptor: | Vacuolar protein sorting-associating protein 4B | Authors: | Inoue, M, Kawasaki, M, Kamikubo, H, Kataoka, M, Kato, R, Yoshimori, T, Wakatsuki, S. | Deposit date: | 2007-10-08 | Release date: | 2008-10-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B Traffic, 9, 2008
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8OOI
| Full composite cryo-EM map of p97/VCP in ADP.Pi state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Cheng, T.C, Sakata, E, Schuetz, A.K. | Deposit date: | 2023-04-05 | Release date: | 2024-01-31 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.61 Å) | Cite: | Characterizing ATP processing by the AAA+ protein p97 at the atomic level. Nat.Chem., 16, 2024
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8RHN
| Structure of the 55LCC ATPase complex | Descriptor: | ATPase family gene 2 protein homolog A, ATPase family gene 2 protein homolog B, Cyclin-dependent kinase 2-interacting protein, ... | Authors: | Foglizzo, M, Degtjarik, O, Zeqiraj, E. | Deposit date: | 2023-12-15 | Release date: | 2024-03-27 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity. Cell, 2024
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8TH8
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2ZAN
| Crystal structure of mouse SKD1/VPS4B ATP-form | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Vacuolar protein sorting-associating protein 4B | Authors: | Inoue, M, Kawasaki, M, Kamikubo, H, Kataoka, M, Kato, R, Yoshimori, T, Wakatsuki, S. | Deposit date: | 2007-10-08 | Release date: | 2008-10-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B Traffic, 9, 2008
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8TID
| Combined linker domain of N-DRC and associated proteins Tetrahymena | Descriptor: | AAA family ATPase CDC48 subfamily protein, CFAP20, Calmodulin 7-2, ... | Authors: | Ghanaeian, A.G, Majhi, S.M, McCaffrey, C.M, Nami, B.N, Black, C.B, Yang, S.K, Legal, T.L, Papoulas, O.P, Janowska, M.J, Valente-Paterno, M.V, Marcotte, E.M, Wloga, D.W, Bui, K.H. | Deposit date: | 2023-07-19 | Release date: | 2023-09-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism. Nat Commun, 14, 2023
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2ZAO
| Crystal structure of mouse SKD1/VPS4B ADP-form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Vacuolar protein sorting-associating protein 4B | Authors: | Inoue, M, Kawasaki, M, Kamikubo, H, Kataoka, M, Kato, R, Yoshimori, T, Wakatsuki, S. | Deposit date: | 2007-10-08 | Release date: | 2008-10-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B Traffic, 9, 2008
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3B9P
| Spastin | Descriptor: | CG5977-PA, isoform A, CHLORIDE ION | Authors: | Roll-Mecak, A, Vale, R.D. | Deposit date: | 2007-11-06 | Release date: | 2008-01-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin. Nature, 451, 2008
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6WJN
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1QVR
| Crystal Structure Analysis of ClpB | Descriptor: | ClpB protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PLATINUM (II) ION | Authors: | Lee, S, Sowa, M.E, Watanabe, Y, Sigler, P.B, Chiu, W, Yoshida, M, Tsai, F.T.F. | Deposit date: | 2003-08-28 | Release date: | 2003-10-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The Structure of ClpB: A Molecular Chaperone that Rescues Proteins from an Aggregated State Cell(Cambridge,Mass.), 115, 2003
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