PDB: 56 resultsInfo pagesStatus searchChemie searchBIRD

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7O9T	Crystal structure of Human Menin in apo form Descriptor: 1,2-ETHANEDIOL, Menin Authors: Groves, M.R, Gao, K. Deposit date: 2021-04-17 Release date: 2022-07-27 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.159 Å) Cite: Crystal structure of Human Menin in apo form To Be Published
7O9X	Crystal structure of Human Menin with fragment 16 Descriptor: (2-methoxyphenyl)methanamine, 1,2-ETHANEDIOL, GLYCEROL, ... Authors: Groves, M.R, Gao, K. Deposit date: 2021-04-17 Release date: 2022-07-27 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.299 Å) Cite: Crystal structure of Human Menin with fragment 16 To Be Published
7O9Z	Crystal structure of Human Menin in complex with BD-08 Descriptor: (~{E})-2-cyano-3-(2~{H}-indazol-6-yl)-~{N}-(2-morpholin-4-ylethyl)prop-2-enamide, 1,2-ETHANEDIOL, GLYCEROL, ... Authors: Groves, M.R, Gao, K. Deposit date: 2021-04-18 Release date: 2022-07-27 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.979 Å) Cite: Crystal structure of Human Menin in complex with BD-08 To Be Published
6BXY	Menin in complex with MI-1481 Descriptor: 1,2-ETHANEDIOL, 4-methyl-1-{[(2S)-5-oxomorpholin-2-yl]methyl}-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile, DIMETHYL SULFOXIDE, ... Authors: Borkin, D, Klossowski, S, Pollock, J, Linhares, B, Cierpicki, T, Grembecka, J. Deposit date: 2017-12-19 Release date: 2018-11-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction. J.Med.Chem., 61, 2018
4FXX	Structure of SF1 coiled-coil domain Descriptor: IMIDAZOLE, MALONATE ION, Splicing factor 1 Authors: Gupta, A, Bauer, W.J, Wang, W, Kielkopf, C.L. Deposit date: 2012-07-03 Release date: 2013-01-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4801 Å) Cite: Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex. Structure, 21, 2013
4FXW	Structure of phosphorylated SF1 complex with U2AF65-UHM domain Descriptor: SULFATE ION, Splicing factor 1, Splicing factor U2AF 65 kDa subunit Authors: Wang, W, Bauer, W.J, Wedekind, J.E, Kielkopf, C.L. Deposit date: 2012-07-03 Release date: 2013-01-16 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex. Structure, 21, 2013

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