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PDB: 400 results

3UCH
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BU of 3uch by Molmil
Crystal structure of a peptidyl-prolyl cis-trans isomerase E (PPIE) from Homo sapiens at 2.50 A resolution
Descriptor: Peptidyl-prolyl cis-trans isomerase E
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2011-10-26
Release date:2011-11-16
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a Hypotherical Peptidyl-prolyl cis-trans isomerase E (PPIE) from Homo sapiens at 2.50 A resolution
To be published
1DYW
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BU of 1dyw by Molmil
Biochemical and structural characterization of a divergent loop cyclophilin from Caenorhabditis elegans
Descriptor: CYCLOPHILIN 3
Authors:Dornan, J, Page, A.P, Taylor, P, Wu, S.Y, Winter, A.D, Husi, H, Walkinshaw, M.D.
Deposit date:2000-02-10
Release date:2000-06-22
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Biochemical and Structural Characterization of a Divergent Loop Cyclophilin from Caenorhabditis Elegans
J.Biol.Chem., 274, 1999
3CYH
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BU of 3cyh by Molmil
CYCLOPHILIN A COMPLEXED WITH DIPEPTIDE SER-PRO
Descriptor: CYCLOPHILIN A, PROLINE, SERINE
Authors:Zhao, Y, Ke, H.
Deposit date:1996-02-27
Release date:1996-07-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanistic implication of crystal structures of the cyclophilin-dipeptide complexes.
Biochemistry, 35, 1996
1E3B
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BU of 1e3b by Molmil
CYCLOPHILIN 3 FROM C.ELEGANS COMPLEXED WITH AUP(ET)3
Descriptor: CYCLOPHILIN 3, GOLD ION, TRIETHYLPHOSPHANE
Authors:Zou, J, Taylor, P, Dornan, J, Robinson, S.P, Walkinshaw, M.D, Sadler, P.J.
Deposit date:2000-06-08
Release date:2000-10-22
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:First Crystal Structure of a Medicinally Relevant Gold Protein Complex:Unexpected Binding of [Au(Pet (3))](+) to Histidine
Angew.Chem.Int.Ed.Engl., 39, 2000
3CYS
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BU of 3cys by Molmil
DETERMINATION OF THE NMR SOLUTION STRUCTURE OF THE CYCLOPHILIN A-CYCLOSPORIN A COMPLEX
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Spitzfaden, C, Braun, W, Wider, G, Widmer, H, Wuthrich, K.
Deposit date:1994-02-28
Release date:1994-08-31
Last modified:2017-11-01
Method:SOLUTION NMR
Cite:Determination of the NMR Solution Structure of the Cyclophilin A-Cyclosporin a Complex.
J.Biomol.NMR, 4, 1994
1E8K
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BU of 1e8k by Molmil
Cyclophilin 3 Complexed With Dipeptide Ala-Pro
Descriptor: ALANINE, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 3, PROLINE
Authors:Wu, S.Y, Dornan, J, Kontopidis, G, Taylor, P, Walkinshaw, M.D.
Deposit date:2000-09-25
Release date:2001-09-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The First Direct Determination of a Ligand Binding Constant in Protein Crystals
Angew.Chem.Int.Ed.Engl., 40, 2001
8EJX
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BU of 8ejx by Molmil
Crystal structure of human cyclophilin D (CypD) with in complex with the covalently bound Ebselen inhibitor
Descriptor: N-phenyl-2-selanylbenzamide, Peptidyl-prolyl cis-trans isomerase F, mitochondrial
Authors:Lovell, S, Battaile, K.P, Yan, S.
Deposit date:2022-09-19
Release date:2023-10-18
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:New cyclophilin D inhibitor rescues mitochondrial and cognitive function in Alzheimer's disease.
Brain, 147, 2024
3EOV
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BU of 3eov by Molmil
Crystal structure of cyclophilin from Leishmania donovani ligated with cyclosporin A
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
Authors:Venugopal, V, Dasgupta, D, Datta, A.K, Banerjee, R.
Deposit date:2008-09-29
Release date:2008-11-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Cyclophilin from Leishmania Donovani Bound to Cyclosporin at 2.6 A Resolution: Correlation between Structure and Thermodynamic Data.
Acta Crystallogr.,Sect.D, 65, 2009
6FK1
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BU of 6fk1 by Molmil
Cyclophilin A
Descriptor: 1,2-ETHANEDIOL, Peptidyl-prolyl cis-trans isomerase A
Authors:Lisboa, J, dos Santos, N.M.S.
Deposit date:2018-01-23
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.299 Å)
Cite:Production, crystallization and structure determination of cyclophilin A from Mus musculus
To Be Published
7L6Y
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BU of 7l6y by Molmil
Crystal Structure of the Peptidyl-Prolyl Cis-Trans Isomerase (PpiB) from Streptococcus pyogenes.
Descriptor: Peptidyl-prolyl cis-trans isomerase
Authors:Minasov, G, Shuvalova, L, Kiryukhina, O, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-12-24
Release date:2021-12-01
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Crystal Structure of the Peptidyl-Prolyl Cis-Trans Isomerase (PpiB) from Streptococcus pyogenes.
To Be Published
7L6Z
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Crystal Structure of Peptidyl-Prolyl Cis-Trans Isomerasefrom (PpiB) Streptococcus pneumoniae R6
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-12-24
Release date:2021-12-01
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal Structure of Peptidyl-Prolyl Cis-Trans Isomerasefrom (PpiB) Streptococcus pneumoniae R6
To Be Published
8B58
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Crystal Structure of Cyclophilin TgCyp23 from Toxoplasma gondii in complex with Cyclosporin A
Descriptor: Cyclosporin A, Peptidyl-prolyl cis-trans isomerase
Authors:Jimenez-Faraco, E, Hermoso, J.A.
Deposit date:2022-09-22
Release date:2023-02-01
Last modified:2023-02-22
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural Basis for Cyclosporin Isoform-Specific Inhibition of Cyclophilins from Toxoplasma gondii .
Acs Infect Dis., 9, 2023
6U5C
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RT XFEL structure of CypA solved using MESH injection system
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Wolff, A.M, Thompson, M.C.
Deposit date:2019-08-27
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals
Iucrj, 7, 2020
6U5E
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BU of 6u5e by Molmil
RT XFEL structure of CypA solved using celloluse carrier media
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Wolff, A.M, Nango, E, Nakane, T, Young, I.D, Brewster, A.S, Sugahara, M, Tanaka, R, Sauter, N.K, Tono, K, Iwata, S, Fraser, J.S, Thompson, M.C.
Deposit date:2019-08-27
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals
Iucrj, 7, 2020
6U5G
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BU of 6u5g by Molmil
MicroED structure of a FIB-milled CypA Crystal
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Wolff, A.M, Martynowycz, M.W, Zhao, W, Gonen, T, Fraser, J.S, Thompson, M.C.
Deposit date:2019-08-27
Release date:2020-01-29
Last modified:2023-10-11
Method:ELECTRON CRYSTALLOGRAPHY (2.5 Å)
Cite:Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals
Iucrj, 7, 2020
6U5D
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BU of 6u5d by Molmil
RT XFEL structure of CypA solved using LCP injection system
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Wolff, A.M, Young, I.D, Sierra, R.G, Brewster, A.S, Koralek, J.D, Boutet, S, Sauter, N.K, Fraser, J.S, Thompson, M.C.
Deposit date:2019-08-27
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals
Iucrj, 7, 2020
7N3J
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BU of 7n3j by Molmil
E. coli peptidyl-prolyl cis-trans isomerase, mutant Phe27CF3-Tyr/Phe98CF3-Tyr
Descriptor: Peptidyl-prolyl cis-trans isomerase B
Authors:Frkic, R.L, Otting, G, Jackson, C.J.
Deposit date:2021-06-01
Release date:2021-09-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Through-Space Scalar 19 F- 19 F Couplings between Fluorinated Noncanonical Amino Acids for the Detection of Specific Contacts in Proteins.
J.Am.Chem.Soc., 143, 2021
8CU5
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Crystal Structure of Putative Cyclophilin B from Brugia malayi
Descriptor: 1,2-ETHANEDIOL, Peptidyl-prolyl cis-trans isomerase, SULFATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-05-16
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of Putative Cyclophilin B from Brugia malayi
to be published
7OGI
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BU of 7ogi by Molmil
Human Cyclophilin D in complex with N-(5-ethyl-4-oxo-1,2,3,4,5,6-hexahydro-1,5-benzodiazocin-8-yl)-7methyl-2-oxo-1H,2H-pyrazolo[1,5-a]pyrimidine-6-carboxamide
Descriptor: DIMETHYL SULFOXIDE, N-(5-ethyl-4-oxidanylidene-1,2,3,6-tetrahydro-1,5-benzodiazocin-8-yl)-7-methyl-2-oxidanylidene-1H-pyrazolo[1,5-a]pyrimidine-6-carboxamide, Peptidyl-prolyl cis-trans isomerase F, ...
Authors:Silva, D.O, Graedler, U, Bandeiras, T.M.
Deposit date:2021-05-06
Release date:2022-06-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:Human Cyclophilin D in complex with N-(5-ethyl-4-oxo-1,2,3,4,5,6-hexahydro-1,5-benzodiazocin-8-yl)-7methyl-2-oxo-1H,2H-pyrazolo[1,5-a]pyrimidine-6-carboxamide
To Be Published
7PCJ
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X-ray structure of CypA-C52AK125C/CsA/aromatic foldamer complex
Descriptor: 8-azanyl-4-(2-methylpropoxy)quinoline-2-carboxylic acid, 8-azanyl-4-(3-azanylpropoxy)quinoline-2-carboxylic acid, 8-azanyl-4-oxidanyl-quinoline-2-carboxylic acid, ...
Authors:Vallade, M, Langlois d'Estaintot, B, Fischer, L, Buratto, J, Savko, M, Huc, I.
Deposit date:2021-08-03
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:X-ray structure of a cystein mutant of Cyclophilin A tethered to an aromatic oligoamide foldamer complexed with Cyclosporin A
To Be Published
8HZ8
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BU of 8hz8 by Molmil
Structure of PPIA in complex with the peptide of NRF2
Descriptor: NRF2 peptide, Peptidyl-prolyl cis-trans isomerase A, N-terminally processed
Authors:Wanyan, W, Hui, M, Jin, H, Lu, W.
Deposit date:2023-01-08
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structure of PPIA in complex with the peptide of NRF2
To Be Published
7PMT
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Human Cyclophilin D in complex with N-[(5-ethyl-4-oxo-1,2,3,4,5,6- hexahydro-1,5-benzodiazocin-8-yl)methyl]-7-methyl-2-oxo-1H,2H-pyrazolo[1,5-a]pyrimidine-6-carboxamide
Descriptor: DIMETHYL SULFOXIDE, Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ...
Authors:Silva, D.O, Graedler, U, Bandeiras, T.M.
Deposit date:2021-09-02
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Human Cyclophilin D in complex with N-[(4-aminophenyl)methyl]-7-methyl-2-oxo-1H,2H-pyrazolo[1,5-a]pyrimidine-6-carboxamide
To Be Published
7Q6P
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Crystal Structure of bacterial Prolyl Peptidyl Isomerase with 5,5'-difluoroleucines
Descriptor: Peptidyl-prolyl cis-trans isomerase B, SULFATE ION
Authors:Tars, K, Jaudzems, K, Recacha, R.
Deposit date:2021-11-09
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal Structure of bacterial Prolyl Peptidyl Isomerase with 5,5'-difluoroleucines
To Be Published
7QBW
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Human Cyclophilin A double mutant C52AK125C
Descriptor: GLYCEROL, Peptidyl-prolyl cis-trans isomerase A
Authors:Fischer, L, Buratto, J, Langlois d'Estaintot, B.
Deposit date:2021-11-19
Release date:2022-11-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Human Cyclophilin A double mutant C52AK125C
To Be Published
2X25
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Free acetyl-CypA orthorhombic form
Descriptor: PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Lammers, M, Neumann, H, Chin, J.W, James, L.C.
Deposit date:2010-01-11
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerization.
Nat.Chem.Biol., 6, 2010

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