PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

Human Ecto-5'-nucleotidase (CD73) in complex with A2396 (compound 74 in publication) in the closed form in crystal form IV
Descriptor:	4-[[5-[7-chloranyl-3-(1~{H}-indazol-6-yl)benzotriazol-5-yl]pyrazol-1-yl]methyl]benzenecarbonitrile, 5'-nucleotidase, CALCIUM ION, ...
Authors:	Strater, N.
Deposit date:	2020-01-19
Release date:	2020-04-22
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (1.94 Å)
Cite:	Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73. J.Med.Chem., 63, 2020

Human Ecto-5'-nucleotidase (CD73) in complex with A2410 (compound 53 in publication) in the closed form in crystal form IV
Descriptor:	4-chloranyl-1-(1~{H}-indazol-6-yl)-6-[2-(3-methylphenyl)pyrazol-3-yl]benzotriazole, 5'-nucleotidase, CALCIUM ION, ...
Authors:	Strater, N.
Deposit date:	2020-01-19
Release date:	2020-04-22
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (2.09 Å)
Cite:	Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73. J.Med.Chem., 63, 2020

Human Ecto-5'-nucleotidase (CD73) in complex with A1618 (compound 1b in publication) in the closed state in crystal form III
Descriptor:	5'-nucleotidase, CALCIUM ION, ZINC ION, ...
Authors:	Strater, N.
Deposit date:	2020-01-20
Release date:	2020-04-22
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (1.97 Å)
Cite:	Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73. J.Med.Chem., 63, 2020