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PDB: 1 results

Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378
Descriptor:	ALK tyrosine kinase receptor, GLYCEROL, N~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Authors:	Lee, C.C, Spraggon, G.
Deposit date:	2015-04-02
Release date:	2016-02-03
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (1.55 Å)
Cite:	Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors. Bioorg.Med.Chem.Lett., 26, 2016