PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket
Descriptor:	(5R)-5-[(5-methoxy-3-oxo-1,3-dihydro-2H-indazol-2-yl)methyl]-5-methylimidazolidine-2,4-dione, Disintegrin and metalloproteinase domain-containing protein 17, ZINC ION
Authors:	Orth, P.
Deposit date:	2009-12-10
Release date:	2010-03-02
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Discovery and SAR of hydantoin TACE inhibitors. Bioorg.Med.Chem.Lett., 20, 2010

Crystal structure of catalytic domain of TACE with hydantoin inhibitor
Descriptor:	Disintegrin and metalloproteinase domain-containing protein 17, ISOPROPYL ALCOHOL, N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide, ...
Authors:	Orth, P.
Deposit date:	2009-12-10
Release date:	2010-03-02
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.92 Å)
Cite:	Discovery and SAR of hydantoin TACE inhibitors. Bioorg.Med.Chem.Lett., 20, 2010