5AOR
 
 | | Structure of MLE RNA ADP AlF4 complex | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, DOSAGE COMPENSATION REGULATOR, ... | | Authors: | Prabu, J.R, Conti, E. | | Deposit date: | 2015-09-11 | | Release date: | 2015-11-18 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structure of the RNA Helicase Mle Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling.
Mol.Cell, 60, 2015
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7Q3L
 | | Human 17S U2 snRNP 5' domain | | Descriptor: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... | | Authors: | Tholen, J, Galej, W.P. | | Deposit date: | 2021-10-28 | | Release date: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Structural basis of branch site recognition by the human spliceosome.
Science, 375, 2022
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7QTT
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7W0B
 | | Dicer2-LoqsPD complex at apo status | | Descriptor: | Dicer-2, isoform A, Loquacious, ... | | Authors: | Su, S, Wang, J, Wang, H.W, Ma, J. | | Deposit date: | 2021-11-18 | | Release date: | 2022-04-27 | | Last modified: | 2022-07-27 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
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7W0E
 | | dmDicer2-LoqsPD-dsRNA Active-dicing status | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ... | | Authors: | Su, S, Wang, J, Wang, H.W, Ma, J. | | Deposit date: | 2021-11-18 | | Release date: | 2022-04-27 | | Last modified: | 2022-07-27 | | Method: | ELECTRON MICROSCOPY (4.03 Å) | | Cite: | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
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7W0D
 | | Dicer2-LoqsPD-dsRNA complex at mid-translocation state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Dicer-2, isoform A, ... | | Authors: | Su, S, Wang, J, Wang, H.W, Ma, J. | | Deposit date: | 2021-11-18 | | Release date: | 2022-04-27 | | Last modified: | 2022-07-27 | | Method: | ELECTRON MICROSCOPY (4.18 Å) | | Cite: | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
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7W0F
 | | dmDicer2-LoqsPD-dsRNA Post-dicing status | | Descriptor: | Dicer-2, isoform A, Loquacious, ... | | Authors: | Su, S, Wang, J, Wang, H.W, Ma, J. | | Deposit date: | 2021-11-18 | | Release date: | 2022-04-27 | | Last modified: | 2022-07-27 | | Method: | ELECTRON MICROSCOPY (4.55 Å) | | Cite: | Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD.
Nature, 607, 2022
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8E5T
 | | Yeast co-transcriptional Noc1-Noc2 RNP assembly checkpoint intermediate | | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | | Authors: | Sanghai, Z.A, Piwowarczyk, R, Vanden Broeck, A, Klinge, S. | | Deposit date: | 2022-08-22 | | Release date: | 2023-04-12 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | A co-transcriptional ribosome assembly checkpoint controls nascent large ribosomal subunit maturation.
Nat.Struct.Mol.Biol., 30, 2023
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7R72
 | | State E1 nucleolar 60S ribosome biogenesis intermediate - Spb4 local model | | Descriptor: | 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... | | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | | Deposit date: | 2021-06-24 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.07 Å) | | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
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7R6Q
 | | State E2 nucleolar 60S ribosome biogenesis intermediate - Foot region model | | Descriptor: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | | Deposit date: | 2021-06-23 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
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7R7A
 | | State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model | | Descriptor: | 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | | Deposit date: | 2021-06-24 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
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7VPX
 | | The cryo-EM structure of the human pre-A complex | | Descriptor: | 5SS, DnaJ homolog subfamily C member 8, PHD finger-like domain-containing protein 5A, ... | | Authors: | Zhang, X, Zhan, X, Shi, Y. | | Deposit date: | 2021-10-18 | | Release date: | 2023-05-03 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
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8EUP
 | | Ytm1 associated 60S nascent ribosome State 1A | | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... | | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | | Deposit date: | 2022-10-19 | | Release date: | 2022-11-30 | | Last modified: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Mol.Cell, 82, 2022
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8EV3
 | | Ytm1 associated 60S nascent ribosome (-Fkbp39) State 1B | | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... | | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | | Deposit date: | 2022-10-19 | | Release date: | 2022-11-30 | | Last modified: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Mol.Cell, 82, 2022
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8ESQ
 | | Ytm1 associated nascent 60S ribosome State 2 | | Descriptor: | 25S rRNA (cytosine-C(5))-methyltransferase nop2, 60S ribosomal protein L13, 60S ribosomal protein L14, ... | | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | | Deposit date: | 2022-10-14 | | Release date: | 2022-11-30 | | Last modified: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Mol.Cell, 82, 2022
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8ETI
 | | Fkbp39 associated 60S nascent ribosome State 1 | | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... | | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | | Deposit date: | 2022-10-17 | | Release date: | 2022-11-30 | | Last modified: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Mol.Cell, 82, 2022
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8EUY
 | | Ytm1 associated nascent 60S ribosome (-fkbp39) State 1A | | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... | | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | | Deposit date: | 2022-10-19 | | Release date: | 2022-11-30 | | Last modified: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Mol.Cell, 82, 2022
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8ETH
 | | Ytm1 associated 60S nascent ribosome State 1B | | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... | | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | | Deposit date: | 2022-10-17 | | Release date: | 2022-11-30 | | Last modified: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Mol.Cell, 82, 2022
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8ETG
 | | Fkbp39 associated 60S nascent ribosome State 3 | | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... | | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | | Deposit date: | 2022-10-17 | | Release date: | 2022-11-30 | | Last modified: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Mol.Cell, 82, 2022
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8ESR
 | | Ytm1 associated nascent 60S ribosome (-fkbp39) State 2 | | Descriptor: | 25S rRNA (cytosine-C(5))-methyltransferase nop2, 60S ribosomal protein L13, 60S ribosomal protein L14, ... | | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | | Deposit date: | 2022-10-14 | | Release date: | 2022-11-30 | | Last modified: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Mol.Cell, 82, 2022
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7V6B
 | | Structure of the Dicer-2-R2D2 heterodimer | | Descriptor: | Dicer-2, isoform A, R2D2 | | Authors: | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | | Deposit date: | 2021-08-20 | | Release date: | 2022-03-23 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.
Nature, 607, 2022
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7V6C
 | | Structure of the Dicer-2-R2D2 heterodimer bound to small RNA duplex | | Descriptor: | Dicer-2, isoform A, R2D2, ... | | Authors: | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | | Deposit date: | 2021-08-20 | | Release date: | 2022-03-23 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.
Nature, 607, 2022
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7W59
 | | The cryo-EM structure of human pre-C*-I complex | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | Authors: | Zhan, X, Lu, Y, Shi, Y. | | Deposit date: | 2021-11-29 | | Release date: | 2022-06-22 | | Last modified: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
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7W5A
 | | The cryo-EM structure of human pre-C*-II complex | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | Authors: | Zhan, X, Lu, Y, Shi, Y. | | Deposit date: | 2021-11-29 | | Release date: | 2022-06-22 | | Last modified: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
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7W5B
 | | The cryo-EM structure of human C* complex | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | Authors: | Zhan, X, Lu, Y, Shi, Y. | | Deposit date: | 2021-11-29 | | Release date: | 2022-06-22 | | Last modified: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
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