3J6F
| Minimized average structure of GDP-bound dynamic microtubules | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. | Deposit date: | 2014-02-19 | Release date: | 2014-06-04 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis. Cell(Cambridge,Mass.), 157, 2014
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3JAS
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3JAT
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3J6H
| Nucleotide-free Kinesin motor domain complexed with GMPCPP-microtubule | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin heavy chain isoform 5C, MAGNESIUM ION, ... | Authors: | Morikawa, M, Yajima, H, Nitta, R, Inoue, S, Ogura, T, Sato, C, Hirokawa, N. | Deposit date: | 2014-02-21 | Release date: | 2015-04-01 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (8.1 Å) | Cite: | X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding Embo J., 2015
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3J6G
| Minimized average structure of microtubules stabilized by taxol | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. | Deposit date: | 2014-02-19 | Release date: | 2014-06-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis. Cell(Cambridge,Mass.), 157, 2014
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3J7I
| Structure of alpha- and beta- tubulin in GMPCPP-microtubules | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Tubulin alpha-1A chain, ... | Authors: | Yajima, H, Ogura, T, Nitta, R, Okada, Y, Sato, C, Hirokawa, N. | Deposit date: | 2014-07-01 | Release date: | 2014-12-10 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy J.Cell Biol., 198, 2012
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3JAR
| Cryo-EM structure of GDP-microtubule co-polymerized with EB3 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Zhang, R, Nogales, E. | Deposit date: | 2015-06-19 | Release date: | 2015-08-12 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins. Cell(Cambridge,Mass.), 162, 2015
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3JAW
| Atomic model of a microtubule seam based on a cryo-EM reconstruction of the EB3-bound microtubule (merged dataset containing tubulin bound to GTPgammaS, GMPCPP, and GDP) | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Zhang, R, Nogales, E. | Deposit date: | 2015-06-30 | Release date: | 2015-08-12 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins. Cell(Cambridge,Mass.), 162, 2015
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5KMG
| Near-atomic cryo-EM structure of PRC1 bound to the microtubule | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Kellogg, E.H, Howes, S, Ti, S.-C, Ramirez-Aportela, E, Kapoor, T.M, Chacon, P, Nogales, E. | Deposit date: | 2016-06-27 | Release date: | 2016-08-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Near-atomic cryo-EM structure of PRC1 bound to the microtubule. Proc.Natl.Acad.Sci.USA, 113, 2016
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5KX5
| Crystal structure of tubulin-stathmin-TTL-Compound 11 complex | Descriptor: | (2~{S},4~{R})-4-[[2-[(1~{R},3~{R})-1-acetyloxy-3-[[(2~{S},3~{S})-2-[[(2~{R})-1,2-dimethylpyrrolidin-2-yl]carbonylamino]-3-methyl-pentanoyl]-methyl-amino]-4-methyl-pentyl]-1,3-thiazol-4-yl]carbonylamino]-5-(4-aminophenyl)-2-methyl-pentanoic acid, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | Authors: | Parris, K. | Deposit date: | 2016-07-20 | Release date: | 2016-12-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads. ACS Med Chem Lett, 7, 2016
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3J1T
| High affinity dynein microtubule binding domain - tubulin complex | Descriptor: | Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ... | Authors: | Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E. | Deposit date: | 2012-06-25 | Release date: | 2012-09-26 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Structural basis for microtubule binding and release by dynein. Science, 337, 2012
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3J1U
| Low affinity dynein microtubule binding domain - tubulin complex | Descriptor: | Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ... | Authors: | Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E. | Deposit date: | 2012-06-25 | Release date: | 2012-09-26 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Structural basis for microtubule binding and release by dynein. Science, 337, 2012
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3J6P
| Pseudo-atomic model of dynein microtubule binding domain-tubulin complex based on a cryoEM map | Descriptor: | Dynein heavy chain, cytoplasmic, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Uchimura, S, Fujii, T, Takazaki, H, Ayukawa, R, Nishikawa, Y, Minoura, I, Hachikubo, Y, Kurisu, G, Sutoh, K, Kon, T, Namba, K, Muto, E. | Deposit date: | 2014-03-20 | Release date: | 2014-12-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | A flipped ion pair at the dynein-microtubule interface is critical for dynein motility and ATPase activation J.Cell Biol., 208, 2015
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3JAL
| Cryo-EM structure of GMPCPP-microtubule co-polymerized with EB3 | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Microtubule-associated protein RP/EB family member 3, ... | Authors: | Zhang, R, Nogales, E. | Deposit date: | 2015-06-16 | Release date: | 2015-08-12 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins. Cell(Cambridge,Mass.), 162, 2015
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3J8X
| High-resolution structure of no-nucleotide kinesin on microtubules | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | Authors: | Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V. | Deposit date: | 2014-11-20 | Release date: | 2014-12-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation. Elife, 3, 2014
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3JAK
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3JAO
| Ciliary microtubule doublet | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Maheshwari, A, Obbineni, J.M, Bui, K.H, Shibata, K, Toyoshima, Y.Y, Ishikawa, T. | Deposit date: | 2015-06-18 | Release date: | 2015-08-05 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (23 Å) | Cite: | alpha- and beta-Tubulin Lattice of the Axonemal Microtubule Doublet and Binding Proteins Revealed by Single Particle Cryo-Electron Microscopy and Tomography. Structure, 23, 2015
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5LA6
| Tubulin-pironetin complex | Descriptor: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Prota, A.E, Setter, J, Waight, A.B, Bargsten, K, Murga, J, Diaz, J.F, Steinmetz, M.O. | Deposit date: | 2016-06-13 | Release date: | 2016-07-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Pironetin Binds Covalently to alpha Cys316 and Perturbs a Major Loop and Helix of alpha-Tubulin to Inhibit Microtubule Formation. J.Mol.Biol., 428, 2016
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3J2U
| Kinesin-13 KLP10A HD in complex with CS-tubulin and a microtubule | Descriptor: | Kinesin-like protein Klp10A, Tubulin alpha-1A chain, Tubulin beta-2B chain | Authors: | Asenjo, A.B, Chatterjee, C, Tan, D, DePaoli, V, Rice, W.J, Diaz-Avalos, R, Silvestry, M, Sosa, H. | Deposit date: | 2013-01-10 | Release date: | 2013-03-06 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (10.8 Å) | Cite: | Structural model for tubulin recognition and deformation by Kinesin-13 microtubule depolymerases. Cell Rep, 3, 2013
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3J8Y
| High-resolution structure of ATP analog-bound kinesin on microtubules | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V. | Deposit date: | 2014-11-20 | Release date: | 2014-12-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation. Elife, 3, 2014
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5LOV
| DZ-2384 tubulin complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, DZ 2384, ... | Authors: | Prota, A.E, Steinmetz, M.O, Shore, G.C, Brouhard, G, Roulston, A. | Deposit date: | 2016-08-10 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity. Sci Transl Med, 8, 2016
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5LXS
| Tubulin-KS-1-199-32 complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Prota, A.E, Steinmetz, M.O. | Deposit date: | 2016-09-22 | Release date: | 2017-09-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis of Microtubule Stabilization by Discodermolide. Chembiochem, 18, 2017
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5LP6
| Crystal structure of Tubulin-Stathmin-TTL-Thiocolchicine Complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Marangon, J, Christodoulou, M, Casagrande, F, Tiana, G, Dalla Via, L, Aliverti, A, Passarella, D, Cappelletti, G, Ricagno, S. | Deposit date: | 2016-08-11 | Release date: | 2016-09-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Tools for the rational design of bivalent microtubule-targeting drugs. Biochem. Biophys. Res. Commun., 479, 2016
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5M54
| Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins | Descriptor: | Calmodulin-regulated spectrin-associated protein 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Akhmanova, A, Moores, C.A, Baldus, M, Steinmetz, M.O, Topf, M, Roberts, A.J, Grant, B.J, Scarabelli, G, Joseph, A.-J, van Hooff, J.J.E, Houben, K, Hua, S, Luo, Y, Stangier, M.M, Jiang, K, Atherton, J. | Deposit date: | 2016-10-20 | Release date: | 2017-10-04 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | A structural model for microtubule minus-end recognition and protection by CAMSAP proteins. Nat. Struct. Mol. Biol., 24, 2017
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5LYJ
| Tubulin-Combretastatin A4 complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Combretastatin A4, ... | Authors: | Gaspari, R, Prota, A.E, Cavalli, A, Steinmetz, M.O. | Deposit date: | 2016-09-28 | Release date: | 2017-01-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.397 Å) | Cite: | Structural basis of cis- and trans-combretastatin binding to tubulin Chem, 2017
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