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3TSZ
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BU of 3tsz by Molmil
crystal structure of PDZ3-SH3-GUK core module from human ZO-1 in complex with 12mer peptide from human JAM-A cytoplasmic tail
Descriptor: Junctional adhesion molecule A, Tight junction protein ZO-1
Authors:Nomme, J, Lavie, A.
Deposit date:2011-09-13
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1.
J.Biol.Chem., 286, 2011
3TSW
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BU of 3tsw by Molmil
crystal structure of the PDZ3-SH3-GUK core module of Human ZO-1
Descriptor: SULFATE ION, Tight junction protein ZO-1
Authors:Nomme, J, Lavie, A.
Deposit date:2011-09-13
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.847 Å)
Cite:The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1.
J.Biol.Chem., 286, 2011
6JJL
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BU of 6jjl by Molmil
Crystal structure of the DegP dodecamer with a modulator
Descriptor: CYS-TYR-ARG-LYS-LEU, Periplasmic serine endoprotease DegP
Authors:Cho, H, Choi, Y, Lee, H.H, Kim, S.
Deposit date:2019-02-26
Release date:2020-09-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy.
Commun Biol, 3, 2020
6JJK
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BU of 6jjk by Molmil
Crystal structure of the DegP dodecamer with a modulator
Descriptor: CYS-TYR-TYR-LYS-ILE, Periplasmic serine endoprotease DegP
Authors:Cho, H, Choi, Y, Lee, H.H, Kim, S.
Deposit date:2019-02-26
Release date:2020-09-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy
Commun Biol, 3, 2020
6JJO
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BU of 6jjo by Molmil
Crystal structure of the DegP dodecamer with a modulator
Descriptor: Periplasmic serine endoprotease DegP, TMB-CYRKL modulator
Authors:Cho, H, Choi, Y, Lee, H.H, Kim, S.
Deposit date:2019-02-26
Release date:2020-09-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.157 Å)
Cite:Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy
Commun Biol, 3, 2020
3SHW
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BU of 3shw by Molmil
Crystal structure of ZO-1 PDZ3-SH3-Guk supramodule complex with Connexin-45 peptide
Descriptor: Gap junction gamma-1 protein, Tight junction protein ZO-1
Authors:Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M.
Deposit date:2011-06-17
Release date:2011-09-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
3STJ
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BU of 3stj by Molmil
Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli
Descriptor: Protease degQ, peptide (UNK)
Authors:Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T.
Deposit date:2011-07-11
Release date:2011-07-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J.Biol.Chem., 286, 2011
6IQR
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BU of 6iqr by Molmil
Crystal structure of Prc with S452I and L252Y mutations
Descriptor: Tail-specific protease
Authors:Chueh, C.K, Chang, C.I.
Deposit date:2018-11-08
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases.
Mbio, 10, 2019
4QL6
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BU of 4ql6 by Molmil
Structure of C. trachomatis CT441
Descriptor: Carboxy-terminal processing protease
Authors:Kohlmann, F, Hilgenfeld, R, Hansen, G.
Deposit date:2014-06-10
Release date:2014-11-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structural basis of the proteolytic and chaperone activity of Chlamydia trachomatis CT441
J.Bacteriol., 197, 2015
6SAK
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BU of 6sak by Molmil
Structure of the OTULINcat C129A - SNX27 PDZ domain complex.
Descriptor: GLYCEROL, SULFATE ION, Sorting nexin-27, ...
Authors:Elliott, P.R, Komander, D.
Deposit date:2019-07-17
Release date:2019-10-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Regulation of the endosomal SNX27-retromer by OTULIN.
Nat Commun, 10, 2019
3OU0
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BU of 3ou0 by Molmil
re-refined 3CS0
Descriptor: Periplasmic serine endoprotease DegP, heptapeptide, pentapeptide
Authors:Sauer, R.T, Grant, R.A, Kim, S.
Deposit date:2010-09-14
Release date:2011-01-19
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Covalent Linkage of Distinct Substrate Degrons Controls Assembly and Disassembly of DegP Proteolytic Cages.
Cell(Cambridge,Mass.), 145, 2011
5E6P
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BU of 5e6p by Molmil
PlexinB2 cytoplasmic region/PDZ-RhoGEF PDZ domain complex
Descriptor: Plexin-B2, Rho guanine nucleotide exchange factor 11
Authors:Pascoe, H.G, Zhang, X.
Deposit date:2015-10-10
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.215 Å)
Cite:Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.
Proc.Natl.Acad.Sci.USA, 112, 2015
3CS0
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BU of 3cs0 by Molmil
Crystal structure of DegP24
Descriptor: Periplasmic serine endoprotease DegP, pentapeptide
Authors:Krojer, T, Sawa, J, Schaefer, E, Saibil, H.R, Ehrmann, M, Clausen, T.
Deposit date:2008-04-08
Release date:2008-05-27
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
1P1D
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BU of 1p1d by Molmil
Structural Insights into the Inter-domain Chaperoning of Tandem PDZ Domains in Glutamate Receptor Interacting Proteins
Descriptor: Glutamate receptor interacting protein
Authors:Feng, W, Shi, Y, Li, M, Zhang, M.
Deposit date:2003-04-12
Release date:2003-11-11
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Tandem PDZ repeats in glutamate receptor-interacting proteins have a novel mode of PDZ domain-mediated target binding
Nat.Struct.Biol., 10, 2003
4L8N
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BU of 4l8n by Molmil
Crystal structure of a PDZ domain protein (BDI_1242) from Parabacteroides distasonis ATCC 8503 at 2.50 A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ETHANOL, MAGNESIUM ION, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2013-06-17
Release date:2013-06-26
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a PDZ domain protein (BDI_1242) from Parabacteroides distasonis ATCC 8503 at 2.50 A resolution
To be published
4P2A
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BU of 4p2a by Molmil
Structure of mouse VPS26A bound to rat SNX27 PDZ domain
Descriptor: MERCURY (II) ION, Sorting nexin-27, Vacuolar protein sorting-associated protein 26A
Authors:Clairfeuille, T, Gallon, M, Mas, C, Ghai, R, Teasdale, R, Cullen, P, Collins, B.
Deposit date:2014-03-03
Release date:2014-09-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.
Proc.Natl.Acad.Sci.USA, 111, 2014
1Z87
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BU of 1z87 by Molmil
solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
Descriptor: Alpha-1-syntrophin
Authors:Yan, J, Xu, W, Wen, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M.
Deposit date:2005-03-30
Release date:2006-01-24
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
7YKF
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BU of 7ykf by Molmil
Crystal structure of MAGI2 PDZ0-GK/pEphexin4 complex
Descriptor: Ephexin4, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
Authors:Zhang, M, Lin, L, Zhu, J.
Deposit date:2022-07-22
Release date:2023-08-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs.
Sci Adv, 9, 2023
7YKI
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BU of 7yki by Molmil
Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR3 peptide
Descriptor: GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ...
Authors:Zhang, M, Lin, L, Zhu, J.
Deposit date:2022-07-22
Release date:2023-08-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs.
Sci Adv, 9, 2023
7YKG
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BU of 7ykg by Molmil
Crystal structure of MAGI2 PDZ0-GK/pSGEF complex
Descriptor: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, SGEF
Authors:Zhang, M, Lin, L, Zhu, J.
Deposit date:2022-07-22
Release date:2023-08-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs.
Sci Adv, 9, 2023
7YKH
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BU of 7ykh by Molmil
Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR2 peptide
Descriptor: GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ...
Authors:Zhang, M, Lin, L, Zhu, J.
Deposit date:2022-07-22
Release date:2023-08-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs.
Sci Adv, 9, 2023
2HGA
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BU of 2hga by Molmil
Solution NMR Structure of Conserved protein MTH1368, Northeast Structural Genomics Consortium Target TT821A
Descriptor: Conserved protein MTH1368
Authors:Liu, G, Lin, Y, Parish, D, Shen, Y, Sukumaran, D, Yee, A, Semesi, A, Arrowsmith, C, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-06-26
Release date:2006-07-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution NMR Structure of Conserved protein MTH1368, Northeast Structural Genomics Consortium Target TT821A
TO BE PUBLISHED
2XKX
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BU of 2xkx by Molmil
Single particle analysis of PSD-95 in negative stain
Descriptor: DISKS LARGE HOMOLOG 4
Authors:Fomina, S, Howard, T.D, Sleator, O.K, Golovanova, M, O'Ryan, L, Leyland, M.L, Grossmann, J.G, Collins, R.F, Prince, S.M.
Deposit date:2010-07-15
Release date:2011-07-20
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (22.9 Å), SOLUTION SCATTERING
Cite:Self-Directed Assembly and Clustering of the Cytoplasmic Domains of Inwardly Rectifying Kir2.1 Potassium Channels on Association with Psd-95
Biochim.Biophys.Acta, 1808, 2011
8BW8
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BU of 8bw8 by Molmil
Crystal structure of the dCNK-SAM-CRIC-PDZ/dHYP-SAM complex
Descriptor: Connector enhancer of KSR protein CNK, GLYCEROL, Protein aveugle
Authors:Maisonneuve, P, Kurinov, I, Sicheri, F.
Deposit date:2022-12-06
Release date:2024-02-21
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction.
Nat.Struct.Mol.Biol., 31, 2024
8BW9
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BU of 8bw9 by Molmil
Cryo-EM structure of the RAF activating complex KSR-MEK-CNK-HYP
Descriptor: Connector enhancer of KSR protein CNK, Dual specificity mitogen-activated protein kinase kinase dSOR1, KSR, ...
Authors:Maisonneuve, P, Fronzes, R, Sicheri, F.
Deposit date:2022-12-06
Release date:2024-02-21
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction.
Nat.Struct.Mol.Biol., 31, 2024

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