PDB: 730 resultsInfo pagesStatus searchChemie searchBIRD

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7GTP	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000688a Descriptor: (4-acetylphenoxy)acetic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (2.47 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GSZ	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMSOA000686b Descriptor: 1-[4-methyl-2-(pyridin-4-yl)-1,3-thiazol-5-yl]methanamine, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.91 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GT7	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMSOA001181b Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1, {2-[(oxan-4-yl)oxy]phenyl}methanol Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.84 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GSR	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with XST00000055b Descriptor: 2-(piperidin-1-yl)benzamide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.69 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GTT	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000148a Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-(3,4-dihydroquinoline-1(2H)-carbothioyl)propanamide, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.93 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GSV	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMSOA000830b Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(ethylamino)benzoic acid, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.92 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GTD	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOMB000110a Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-[2-(4-chlorophenyl)ethyl]hydrazinecarbothioamide, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.91 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GSW	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with XST00000422b Descriptor: (3M)-3-(furan-2-yl)benzoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.79 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GTR	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000587a Descriptor: 2-(benzyloxy)benzohydrazide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.78 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GSQ	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOMB000149a Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-[(4-chlorophenyl)methyl]methanesulfonamide, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.73 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GTE	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with XST00000646b Descriptor: (5S)-5-(trifluoromethyl)-1,4-diazepane, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GTU	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOMB000297a Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[(2-acetylphenyl)sulfanyl]benzoic acid, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (2.08 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GST	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOMB000056a Descriptor: 1-(methanesulfonyl)-1,2,3,4-tetrahydroquinoline, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.64 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GT6	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOOA000530a Descriptor: (3aS,8aS)-6-benzoyloctahydropyrrolo[3,4-d]azepin-1(2H)-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.66 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GSY	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMSOA001175b Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-[(pyridin-2-yl)oxy]benzonitrile, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.97 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GTH	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOOA000637a Descriptor: (6aR,8R,12R,12aS)-2-methyl-6a,10,11,12a-tetrahydro-6H,7H,9H-[1]benzopyrano[4,3-c]pyrazolo[1,2-a]pyrazol-9-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.66 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GSN	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with XST00000519b Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-[(thiophen-2-yl)methyl]benzoic acid, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.87 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GT0	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOMB000275a Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-benzyl-N'-methyl-N-[(pyridin-3-yl)methyl]thiourea, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.76 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GT2	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with XST00000752b Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1, [(4-chlorophenyl)sulfanyl]acetic acid Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GTF	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with XST00000754b Descriptor: 1,2-benzoxazol-3-ol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.97 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GTV	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with XST00000765c Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 9~{H}-xanthene-9-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.72 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
8XQD	The Crystal Structure of PTPRG from Biortus. Descriptor: Receptor-type tyrosine-protein phosphatase gamma Authors: Wang, F, Cheng, W, Lv, Z, Ju, C, Ni, C. Deposit date: 2024-01-05 Release date: 2024-03-06 Method: X-RAY DIFFRACTION (2.55 Å) Cite: The Crystal Structure of PTPRG from Biortus. To Be Published
7GU4	PanDDA analysis group deposition of ground-state model of PTP1B, using pre-clustering, cluster11 Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-05 Release date: 2024-01-31 Method: X-RAY DIFFRACTION (1.59 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
7GTY	PanDDA analysis group deposition of ground-state model of PTP1B, using pre-clustering, cluster3 Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-05 Release date: 2024-01-31 Method: X-RAY DIFFRACTION (1.54 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published
7GU3	PanDDA analysis group deposition of ground-state model of PTP1B, using pre-clustering, cluster9 Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-05 Release date: 2024-01-31 Method: X-RAY DIFFRACTION (1.74 Å) Cite: PanDDA analysis group deposition of ground-state model To Be Published

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