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6F4H
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BU of 6f4h by Molmil
Crystal structure of the Drosophila melanogaster SNF/U1-SL2 complex
Descriptor: CITRATE ANION, U1 small nuclear ribonucleoprotein A, U1-SL2
Authors:Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C.
Deposit date:2017-11-29
Release date:2018-06-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
6F4G
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BU of 6f4g by Molmil
'Crystal structure of the Drosophila melanogaster SNF/U2A'/U2-SL4 complex
Descriptor: CHLORIDE ION, Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ...
Authors:Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C.
Deposit date:2017-11-29
Release date:2018-06-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
6F4J
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BU of 6f4j by Molmil
Crystal structure of Drosophila melanogaster SNF/U2A' complex
Descriptor: POLYETHYLENE GLYCOL (N=34), Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ...
Authors:Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C.
Deposit date:2017-11-29
Release date:2018-06-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
6F4I
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BU of 6f4i by Molmil
Crystal structure of Drosophila melanogaster SNF
Descriptor: U1 small nuclear ribonucleoprotein A
Authors:Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C.
Deposit date:2017-11-29
Release date:2018-06-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
6DCL
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BU of 6dcl by Molmil
Crystal structure of UP1 bound to pri-miRNA-18a terminal loop
Descriptor: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3')
Authors:Kooshapur, H, Sattler, M.
Deposit date:2018-05-07
Release date:2018-06-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.
Nat Commun, 9, 2018
5YLZ
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BU of 5ylz by Molmil
Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y.
Deposit date:2017-10-20
Release date:2018-07-18
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae
Cell, 171, 2017
5Y88
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BU of 5y88 by Molmil
Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.cerevisiae at 3.5 angstrom
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat, ...
Authors:Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y.
Deposit date:2017-08-20
Release date:2018-08-01
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Structure of an Intron Lariat Spliceosome from Saccharomyces cerevisiae
Cell(Cambridge,Mass.), 171, 2017
5YZG
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BU of 5yzg by Molmil
The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y.
Deposit date:2017-12-14
Release date:2018-08-08
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of a human catalytic step I spliceosome
Science, 359, 2018
6G90
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BU of 6g90 by Molmil
Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2)
Descriptor: 56 kDa U1 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing factor 39, ...
Authors:Plaschka, C, Lin, P.-C, Charenton, C, Nagai, K.
Deposit date:2018-04-10
Release date:2018-08-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Prespliceosome structure provides insights into spliceosome assembly and regulation.
Nature, 559, 2018
6FF4
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BU of 6ff4 by Molmil
human Bact spliceosome core structure
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H.
Deposit date:2018-01-03
Release date:2018-08-29
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
5ZWO
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BU of 5zwo by Molmil
Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom
Descriptor: 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ...
Authors:Bai, R, Wan, R, Yan, C, Shi, Y.
Deposit date:2018-05-16
Release date:2018-08-29
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
5ZWN
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BU of 5zwn by Molmil
Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 angstrom (Part II: U1 snRNP region)
Descriptor: 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Pre-mRNA-splicing ATP-dependent RNA helicase PRP28, ...
Authors:Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y.
Deposit date:2018-05-16
Release date:2018-08-29
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
5ZWM
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BU of 5zwm by Molmil
Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom (tri-snRNP and U2 snRNP Part)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, ...
Authors:Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y.
Deposit date:2018-05-16
Release date:2018-08-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
6FQ1
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BU of 6fq1 by Molmil
Crystal structure of the RRM12 domain of IMP3
Descriptor: 1,2-ETHANEDIOL, Insulin-like growth factor 2 mRNA-binding protein 3
Authors:Jia, M, Gut, H, Chao, A.J.
Deposit date:2018-02-12
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Structural basis of IMP3 RRM12 recognition of RNA.
RNA, 24, 2018
6FQR
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BU of 6fqr by Molmil
Crystal structure of IMP3 RRM12 in complex with RNA (CCCC)
Descriptor: Insulin-like growth factor 2 mRNA-binding protein 3, RNA CCCC
Authors:Jia, M, Gut, H, Chao, A.J.
Deposit date:2018-02-14
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of IMP3 RRM12 recognition of RNA.
RNA, 24, 2018
6GML
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BU of 6gml by Molmil
Structure of paused transcription complex Pol II-DSIF-NELF
Descriptor: DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Vos, S.M, Farnung, L, Urlaub, H, Cramer, P.
Deposit date:2018-05-27
Release date:2018-09-05
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of paused transcription complex Pol II-DSIF-NELF.
Nature, 560, 2018
6GX6
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BU of 6gx6 by Molmil
Crystal structure of IMP3 RRM12 in complex with RNA (ACAC)
Descriptor: 1,2-ETHANEDIOL, Insulin-like growth factor 2 mRNA-binding protein 3, PHOSPHATE ION, ...
Authors:Jia, M, Gut, H, Chao, A.J.
Deposit date:2018-06-26
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of IMP3 RRM12 recognition of RNA.
RNA, 24, 2018
6DG1
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BU of 6dg1 by Molmil
NMR structure of the second qRRM2 domain of human hnRNP H
Descriptor: qRRM2 domain of Heterogeneous nuclear ribonucleoprotein H2
Authors:Srinivasa, R.P.
Deposit date:2018-05-16
Release date:2018-09-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Differential Conformational Dynamics Encoded by the Inter-qRRM linker of hnRNP H.
J. Am. Chem. Soc., 2018
6DHS
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BU of 6dhs by Molmil
Structure of hnRNP H qRRM1,2
Descriptor: Heterogeneous nuclear ribonucleoprotein H
Authors:Meagher, J.L, Stuckey, J.A.
Deposit date:2018-05-21
Release date:2018-09-12
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Differential Conformational Dynamics Encoded by the Inter-qRRM linker of hnRNP H.
J. Am. Chem. Soc., 2018
5Z56
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BU of 5z56 by Molmil
cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom.
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y.
Deposit date:2018-01-17
Release date:2018-09-19
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
5Z58
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BU of 5z58 by Molmil
Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom.
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y.
Deposit date:2018-01-17
Release date:2018-09-19
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
5Z57
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BU of 5z57 by Molmil
Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ...
Authors:Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y.
Deposit date:2018-01-17
Release date:2018-09-19
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
6ELD
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BU of 6eld by Molmil
Crystal structure of TIA-1 RRM1 in complex with U1C
Descriptor: Nucleolysin TIA-1 isoform p40,U1 small nuclear ribonucleoprotein C
Authors:Jagtap, P.K.A, Sattler, M.
Deposit date:2017-09-28
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.485 Å)
Cite:Crystal structure of TIA-1 RRM1 in complex with U1C
To Be Published
6GD2
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BU of 6gd2 by Molmil
Structure of HuR RRM3 in complex with RNA
Descriptor: ELAV-like protein 1, RNA (5'-R(P*UP*UP*UP*AP*UP*UP*U)-3')
Authors:Pabis, M, Sattler, M.
Deposit date:2018-04-21
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
6GD3
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BU of 6gd3 by Molmil
Structure of HuR RRM3 in complex with RNA (UAUUUA)
Descriptor: ELAV-like protein 1, RNA (5'-R(P*UP*AP*UP*UP*UP*A)-3'), SODIUM ION
Authors:Pabis, M, Sattler, M.
Deposit date:2018-04-21
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019

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