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2PKT
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BU of 2pkt by Molmil
Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Uppenberg, J, Gileadi, C, Elkins, J, Bray, J, Burgess-Brown, N, Salah, E, Gileadi, O, Bunkoczi, G, Ugochukwu, E, Umeano, C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2007-04-18
Release date:2007-05-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms
Protein Sci., 19, 2010
2PDZ
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BU of 2pdz by Molmil
SOLUTION STRUCTURE OF THE SYNTROPHIN PDZ DOMAIN IN COMPLEX WITH THE PEPTIDE GVKESLV, NMR, 15 STRUCTURES
Descriptor: PEPTIDE GVKESLV, SYNTROPHIN
Authors:Schultz, J, Hoffmueller, U, Ashurst, J, Krause, G, Schmieder, P, Macias, M, Schneider-Mergener, J, Oschkinat, H.
Deposit date:1997-12-10
Release date:1998-12-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Specific interactions between the syntrophin PDZ domain and voltage-gated sodium channels.
Nat.Struct.Biol., 5, 1998
2PA1
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BU of 2pa1 by Molmil
Structure of the PDZ domain of human PDLIM2 bound to a C-terminal extension from human beta-tropomyosin
Descriptor: CHLORIDE ION, PDZ and LIM domain protein 2
Authors:Uppenberg, J, Shrestha, L, Elkins, J, Burgess-Brown, N, Salah, E, Bunkoczi, G, Papagrigoriou, E, Pike, A.C.W, Turnbull, A.P, Ugochukwu, E, Umeano, C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2007-03-27
Release date:2007-05-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms
Protein Sci., 19, 2010
2OZF
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BU of 2ozf by Molmil
The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1)
Descriptor: Ezrin-radixin-moesin-binding phosphoprotein 50
Authors:Phillips, C, Papagrigoriou, E, Gileadi, C, Fedorov, O, Elkins, J, Berridge, G, Turnbull, A.P, Gileadi, O, Schoch, G, Smee, C, Bray, J, Savitsky, P, Uppenberg, J, von Delft, F, Gorrec, F, Umeano, C, Salah, E, Colebrook, S, Weigelt, J, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2007-02-26
Release date:2007-03-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1)
To be Published
2OSG
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BU of 2osg by Molmil
Solution Structure and Binding Property of the Domain-swapped Dimer of ZO2PDZ2
Descriptor: Tight junction protein ZO-2
Authors:Wu, J.W, Yang, Y.S, Zhang, J.H, Ji, P, Wu, J.H, Shi, Y.Y.
Deposit date:2007-02-05
Release date:2007-09-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Domain-swapped Dimerization of the Second PDZ Domain of ZO2 May Provide a Structural Basis for the Polymerization of Claudins
J.Biol.Chem., 282, 2007
2OS6
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BU of 2os6 by Molmil
Solution structure of LARG PDZ domain in complex with C-terminal octa-peptide of Plexin B1
Descriptor: C-terminal peptide of Plexin-B1, Rho guanine nucleotide exchange factor 12
Authors:Liu, J, Huang, H, Yang, Y.
Deposit date:2007-02-05
Release date:2008-02-12
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the LARG PDZ domain in complex with C-terminal peptide of Plexin B1
To be Published
2OQS
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BU of 2oqs by Molmil
Structure of the hDLG/SAP97 PDZ2 in complex with HPV-18 papillomavirus E6 peptide
Descriptor: C-terminal HPV-18 E6 peptide, Disks large homolog 1
Authors:Liu, Y, Baleja, J.D, Henry, G.D, Hegde, R.S.
Deposit date:2007-02-01
Release date:2007-09-04
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the hDlg/SAP97 PDZ2 domain and its mechanism of interaction with HPV-18 papillomavirus E6 protein.
Biochemistry, 46, 2007
2OPG
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BU of 2opg by Molmil
The crystal structure of the 10th PDZ domain of MPDZ
Descriptor: Multiple PDZ domain protein, SODIUM ION
Authors:Gileadi, C, Phillips, C, Elkins, J, Papagrigoriou, E, Ugochukwu, E, Gorrec, F, Savitsky, P, Umeano, C, Berridge, G, Gileadi, O, Salah, E, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2007-01-29
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of the 10th PDZ domain of MPDZ
To be Published
2OMJ
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BU of 2omj by Molmil
solution structure of LARG PDZ domain
Descriptor: Rho guanine nucleotide exchange factor 12
Authors:Liu, J, Huang, H, Hu, Q.
Deposit date:2007-01-22
Release date:2008-01-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:solution structure and dynamics of the LARG PDZ domain
To be Published
2OGP
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BU of 2ogp by Molmil
Solution structure of the second PDZ domain of Par-3
Descriptor: Partitioning-defective 3 homolog
Authors:Feng, W, Wu, H, Chen, J, Chan, L.-N, Zhang, M.
Deposit date:2007-01-07
Release date:2007-12-25
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:PDZ domains of par-3 as potential phosphoinositide signaling integrators
Mol.Cell, 28, 2007
2OCS
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BU of 2ocs by Molmil
The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2)
Descriptor: 1,2-ETHANEDIOL, Na(+)/H(+) exchange regulatory cofactor NHE-RF2, THIOCYANATE ION
Authors:Papagrigoriou, E, Phillips, C, Gileadi, C, Elkins, J, Salah, E, Berridge, G, Savitsky, P, Gorrec, F, Umeano, C, Ugochukwu, E, Gileadi, O, Burgess, N, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2006-12-21
Release date:2007-01-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2)
To be Published
2O2T
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BU of 2o2t by Molmil
The crystal structure of the 1st PDZ domain of MPDZ
Descriptor: Multiple PDZ domain protein
Authors:Papagrigoriou, E, Gileadi, C, Phillips, C, Johansson, C, Salah, E, Savitsky, P, Gorrec, F, Umeano, C, Berridge, G, Pike, A.C.W, Elkins, J, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2006-11-30
Release date:2006-12-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of the 1st PDZ domain of MPDZ
To be Published
2MX6
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BU of 2mx6 by Molmil
Complex structure of Dvl PDZ domain with ligand
Descriptor: (PHQ)WV peptide, Segment polarity protein dishevelled homolog DVL-1
Authors:Zhang, X, Zheng, J.J.
Deposit date:2014-12-15
Release date:2015-12-30
Method:SOLUTION NMR
Cite:Protein-ligand interaction decoded by NMR chemical shift analysis
To be Published
2MHO
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BU of 2mho by Molmil
Solution State Structure PSD-95 PDZ1 with 5HT2C Receptor peptide
Descriptor: Disks large homolog 4, peptide from 5-hydroxytryptamine receptor 2C
Authors:Dorr, L.A, Phelan, M.M, Lian, L.
Deposit date:2013-11-29
Release date:2014-03-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Interactions of the 5-Hydroxytryptamine Receptor 2a and 2c Variants with the PSD-MAGUK proteins, PSD-95 and SAP997
To be Published
2M3M
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BU of 2m3m by Molmil
Solution structure of a complex consisting of hDlg/SAP-97 residues 318-406 and HPV51 oncoprotein E6 residues 141-151
Descriptor: Disks large homolog 1, Protein E6
Authors:Mischo, A, Ohlenschlager, O, Gorlach, M.
Deposit date:2013-01-22
Release date:2013-05-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural insights into a wildtype domain of the oncoprotein E6 and its interaction with a PDZ domain.
Plos One, 8, 2013
2M10
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BU of 2m10 by Molmil
trans form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative
Descriptor: 3,3'-(E)-diazene-1,2-diylbis{6-[(chloroacetyl)amino]benzenesulfonic acid}, Tyrosine-protein phosphatase non-receptor type 13
Authors:Walser, R.
Deposit date:2012-11-09
Release date:2013-07-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Kinetic response of a photoperturbed allosteric protein.
Proc.Natl.Acad.Sci.USA, 110, 2013
2M0Z
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BU of 2m0z by Molmil
cis form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative
Descriptor: 3,3'-(E)-diazene-1,2-diylbis{6-[(chloroacetyl)amino]benzenesulfonic acid}, Tyrosine-protein phosphatase non-receptor type 13
Authors:Walser, R, Zerbe, O, Hamm, P.
Deposit date:2012-11-09
Release date:2013-07-03
Last modified:2013-08-07
Method:SOLUTION NMR
Cite:Kinetic response of a photoperturbed allosteric protein.
Proc.Natl.Acad.Sci.USA, 110, 2013
2M0V
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BU of 2m0v by Molmil
Complex structure of C-terminal CFTR peptide and extended PDZ2 domain from NHERF1
Descriptor: C-terminal CFTR peptide, Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Authors:Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z.
Deposit date:2012-11-06
Release date:2013-04-24
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
2M0U
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BU of 2m0u by Molmil
Complex structure of C-terminal CFTR peptide and extended PDZ1 domain from NHERF1
Descriptor: C-terminal CFTR peptide, Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Authors:Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z.
Deposit date:2012-11-06
Release date:2013-04-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
2M0T
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BU of 2m0t by Molmil
Structural characterization of the extended PDZ1 domain from NHERF1
Descriptor: Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Authors:Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z.
Deposit date:2012-11-06
Release date:2013-04-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
2LUI
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BU of 2lui by Molmil
Structure of the PICK PDZ domain in complex with the DAT C-terminal
Descriptor: PICK1 PDZ DOMAIN FUSED TO THE C10 DAT LIGAND
Authors:Erlendsson, S, Rathje, M, Heidarsson, P.O, Poulsen, F.M, Madsen, K.L, Teilum, K, Gether, U.
Deposit date:2012-06-14
Release date:2013-06-19
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands.
J.Biol.Chem., 289, 2014
2LOB
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BU of 2lob by Molmil
PDZ Domain of CAL (Cystic Fibrosis Transmembrane Regulator-Associated Ligand)
Descriptor: Cystic fibrosis transmembrane conductance regulator, Golgi-associated PDZ and coiled-coil motif-containing protein
Authors:Piserchio, A, Fellows, A, Madden, D.R, Mierke, D.F.
Deposit date:2012-01-20
Release date:2012-06-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Association of the cystic fibrosis transmembrane regulator with CAL: structural features and molecular dynamics.
Biochemistry, 44, 2005
2LC7
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BU of 2lc7 by Molmil
Solution structure of the isolated Par-6 PDZ domain
Descriptor: Par-6
Authors:Volkman, B.F, Whitney, D.S, Peterson, F.C.
Deposit date:2011-04-25
Release date:2011-11-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A Conformational Switch in the CRIB-PDZ Module of Par-6.
Structure, 19, 2011
2LC6
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BU of 2lc6 by Molmil
Solution structure of Par-6 Q144C/L164C
Descriptor: Par-6
Authors:Volkman, B.F, Whitney, D.S, Peterson, F.C.
Deposit date:2011-04-25
Release date:2011-11-30
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Conformational Switch in the CRIB-PDZ Module of Par-6.
Structure, 19, 2011
2LA8
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BU of 2la8 by Molmil
Solution structure of INAD PDZ5 complexed with Kon-tiki peptide
Descriptor: Inactivation-no-after-potential D protein,kon-tiki peptide
Authors:Zhang, M, Wen, W.
Deposit date:2011-03-08
Release date:2011-11-30
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye
Cell(Cambridge,Mass.), 145, 2011

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