7SK8
| Cryo-EM structure of human ACKR3 in complex with CXCL12, a small molecule partial agonist CCX662, an extracellular Fab, and an intracellular Fab | Descriptor: | (1R)-4-[7-(3-carboxypropoxy)-6-methylquinolin-8-yl]-1-{[2-(4-hydroxypiperidin-1-yl)-1,3-thiazol-4-yl]methyl}-1,4-diazepan-1-ium, Atypical chemokine receptor 3, CHOLESTEROL, ... | Authors: | Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G. | Deposit date: | 2021-10-19 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv, 8, 2022
|
|
7SK3
| Cryo-EM structure of ACKR3 in complex with CXCL12, an intracellular Fab, and an extracellular Fab | Descriptor: | Atypical chemokine receptor 3, CHOLESTEROL, CID24 Fab heavy chain, ... | Authors: | Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G. | Deposit date: | 2021-10-19 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv, 8, 2022
|
|
7SK6
| Cryo-EM structure of human ACKR3 in complex with chemokine N-terminal mutant CXCL12_LRHQ and an intracellular Fab | Descriptor: | Atypical chemokine receptor 3, CID24 Fab heavy chain, CID24 Fab light chain, ... | Authors: | Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G. | Deposit date: | 2021-10-19 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv, 8, 2022
|
|
7SK4
| Cryo-EM structure of ACKR3 in complex with chemokine N-terminal mutant CXCL12_LRHQ, an intracellular Fab, and an extracellular Fab | Descriptor: | Atypical chemokine receptor 3, CHOLESTEROL, CID24 Fab heavy chain, ... | Authors: | Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G. | Deposit date: | 2021-10-19 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv, 8, 2022
|
|