7WCY
| Crystal Structure of H-2Kb with Cryptosporidium parvum gp40/15 epitope | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ... | Authors: | Wang, Y.L, Gao, M.H, Zhang, L.X, Fan, S.H. | Deposit date: | 2021-12-20 | Release date: | 2022-12-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structural Analyses of a Dominant Cryptosporidium parvum Epitope Presented by H-2K b Offer New Options To Combat Cryptosporidiosis. Mbio, 14, 2023
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3TBM
| Crystal structure of a type 4 CDGSH iron-sulfur protein. | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, L(+)-TARTARIC ACID, NONAETHYLENE GLYCOL, ... | Authors: | Lin, J, Zhang, L, Ye, K. | Deposit date: | 2011-08-07 | Release date: | 2011-10-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.797 Å) | Cite: | Structure and Molecular Evolution of CDGSH Iron-Sulfur Domains. Plos One, 6, 2011
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7VWP
| Structure of the flavin-dependent monooxygenase FlsO1 from the biosynthesis of fluostatinsin | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, FlsO1, PHOSPHATE ION, ... | Authors: | Zhang, Y, Yang, C, Zhang, L, Zhang, C. | Deposit date: | 2021-11-11 | Release date: | 2022-09-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Biochemical and structural insights of multifunctional flavin-dependent monooxygenase FlsO1-catalyzed unexpected xanthone formation Nat Commun, 13, 2022
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6J8W
| Structure of MOEN5-SSO7D fusion protein in complex with lig 1 | Descriptor: | (2S)-3-dimethoxyphosphoryloxy-2-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienoxy]propanoic acid, MoeN5,DNA-binding protein 7d | Authors: | Ko, T.P, Zhang, L.L, Chen, C.C, Guo, R.T. | Deposit date: | 2019-01-21 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism. Biochem. Biophys. Res. Commun., 511, 2019
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6J8V
| Structure of MOEN5-SSO7D fusion protein in complex with ligand 2 | Descriptor: | FARNESYL, MoeN5,DNA-binding protein 7d | Authors: | Ko, T.P, Zhang, L.L, Chen, C.C, Guo, R.T. | Deposit date: | 2019-01-21 | Release date: | 2019-04-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism. Biochem. Biophys. Res. Commun., 511, 2019
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7EBS
| Crystal structure of juvenile hormone acid methyltransferase JHAMT from silkworm | Descriptor: | Juvenile hormone acid methyltransferase | Authors: | Guo, P.C, Zhang, Y.S, Zhang, L, Xu, H.Y, Xia, Q.Y. | Deposit date: | 2021-03-11 | Release date: | 2021-09-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase. J.Biol.Chem., 297, 2021
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8PO8
| Structure of Escherichia coli HrpA in complex with ADP and oligonucleotide poly(dC)11 forming an i-motif | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase HrpA, DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), ... | Authors: | Xin, B.G, Yuan, L.G, Zhang, L.L, Xie, S.M, Liu, N.N, Ai, X, Li, H.H, Rety, S, Xi, X.G. | Deposit date: | 2023-07-03 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Structural insights into the N-terminal APHB domain of HrpA: mediating canonical and i-motif recognition. Nucleic Acids Res., 52, 2024
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8UNH
| Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Sliding clamp, ... | Authors: | Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J. | Deposit date: | 2023-10-19 | Release date: | 2023-12-13 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nat.Struct.Mol.Biol., 31, 2024
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8UNF
| Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp and DNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Sliding clamp, ... | Authors: | Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J. | Deposit date: | 2023-10-18 | Release date: | 2023-12-13 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nat.Struct.Mol.Biol., 31, 2024
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6J5I
| Cryo-EM structure of the mammalian DP-state ATP synthase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit epsilon, ... | Authors: | Gu, J, Zhang, L, Yi, J, Yang, M. | Deposit date: | 2019-01-11 | Release date: | 2019-06-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Science, 364, 2019
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6J54
| Cryo-EM structure of the mammalian E-state ATP synthase FO section | Descriptor: | ATP synthase membrane subunit 6.8PL, ATP synthase membrane subunit DAPIT, ATP synthase peripheral stalk-membrane subunit b, ... | Authors: | Gu, J, Zhang, L, Yi, J, Yang, M. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.94 Å) | Cite: | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Science, 364, 2019
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6J5A
| Cryo-EM structure of the mammalian DP-state ATP synthase FO section | Descriptor: | ATP synthase membrane subunit 6.8PL, ATP synthase membrane subunit DAPIT, ATP synthase peripheral stalk-membrane subunit b, ... | Authors: | Gu, J, Zhang, L, Yi, J, Yang, M. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.35 Å) | Cite: | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Science, 364, 2019
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6J5K
| Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit alpha, ... | Authors: | Gu, J, Zhang, L, Yi, J, Yang, M. | Deposit date: | 2019-01-11 | Release date: | 2019-06-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Science, 364, 2019
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6J5J
| Cryo-EM structure of the mammalian E-state ATP synthase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit epsilon, ... | Authors: | Gu, J, Zhang, L, Yi, J, Yang, M. | Deposit date: | 2019-01-11 | Release date: | 2019-06-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Science, 364, 2019
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8PO6
| Structure of Escherichia coli HrpA apo form | Descriptor: | ATP-dependent RNA helicase HrpA, PHOSPHATE ION | Authors: | Xin, B.G, Yuan, L.G, Zhang, L.L, Xie, S.M, Liu, N.N, Ai, X, Li, H.H, Rety, S, Xi, X.G. | Deposit date: | 2023-07-03 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Structural insights into the N-terminal APHB domain of HrpA: mediating canonical and i-motif recognition. Nucleic Acids Res., 52, 2024
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8PO7
| Structure of Escherichia coli HrpA in complex with ADP and dinucleotide dCdC | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase HrpA, DNA (5'-D(P*CP*C)-3'), ... | Authors: | Xin, B.G, Yuan, L.G, Zhang, L.L, Xie, S.M, Liu, N.N, Ai, X, Li, H.H, Rety, S, Xi, X.G. | Deposit date: | 2023-07-03 | Release date: | 2024-05-08 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structural insights into the N-terminal APHB domain of HrpA: mediating canonical and i-motif recognition. Nucleic Acids Res., 52, 2024
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7VPN
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7W5P
| Crystal Structure of the dioxygenase CcTet from Coprinopsis cinereain bound to 12bp N6-methyldeoxyadenine (6mA) containing duplex DNA | Descriptor: | CcTet, DNA, DNA (12-MER), ... | Authors: | Mu, Y.J, Zhang, L, Zhang, L. | Deposit date: | 2021-11-30 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA. Nat.Chem.Biol., 18, 2022
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4KT8
| The complex structure of Rv3378c-Y51FY90F with substrate, TPP | Descriptor: | (2E)-3-methyl-5-[(1R,2S,8aS)-1,2,5,5-tetramethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-1-yl]pent-2-en-1-yl trihydrogen diphosphate, Diterpene synthase, PHOSPHATE ION | Authors: | Chan, H.C, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Zheng, Y, Bogue, S, Nakano, C, Hoshino, T, Zhang, L, Lv, P, Liu, W, Crick, D.C, Liang, P.H, Wang, A.H, Oldfield, E, Guo, R.T. | Deposit date: | 2013-05-20 | Release date: | 2014-02-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc., 136, 2014
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7XSP
| Structure of gRAMP-target RNA | Descriptor: | RAMP superfamily protein, RNA (35-MER), RNA (5'-R(P*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*G)-3'), ... | Authors: | Feng, Y, Zhang, L.X. | Deposit date: | 2022-05-15 | Release date: | 2022-11-09 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Target RNA activates the protease activity of Craspase to confer antiviral defense. Mol.Cell, 82, 2022
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7EW9
| GDP-bound KRAS G12D in complex with TH-Z816 | Descriptor: | 7-(8-methylnaphthalen-1-yl)-4-[(2~{R})-2-methylpiperazin-1-yl]-2-[[(2~{S})-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidine, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | Authors: | Shen, P, Yang, Y, Yang, Y, Zhang, L, Chen, C.-C, Guo, R.-T. | Deposit date: | 2021-05-25 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge. Cell Discov, 8, 2022
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7EWB
| GDP-bound KRAS G12D in complex with TH-Z835 | Descriptor: | 4-[(1~{S},5~{R})-3,8-diazabicyclo[3.2.1]octan-3-yl]-7-(8-methylnaphthalen-1-yl)-2-[[(2~{S})-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidine, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | Authors: | Shen, P, Yang, Y, Yang, Y, Zhang, L, Chen, C.-C, Guo, R.-T. | Deposit date: | 2021-05-25 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge. Cell Discov, 8, 2022
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7EWA
| GDP-bound KRAS G12D in complex with TH-Z827 | Descriptor: | 4-[(1~{R},5~{S})-3,8-diazabicyclo[3.2.1]octan-8-yl]-7-(8-methylnaphthalen-1-yl)-2-[[(2~{S})-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidine, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | Authors: | Shen, P, Yang, Y, Yang, Y, Zhang, L, Chen, C.-C, Guo, R.-T. | Deposit date: | 2021-05-25 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge. Cell Discov, 8, 2022
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7Y4H
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5UP8
| Crystal Structure of the Zn-bound Human Heavy-Chain variant 122H-delta C-star with para-benzenedihydroxamate | Descriptor: | Ferritin heavy chain, N,N'-dihydroxybenzene-1,4-dicarboxamide, SODIUM ION, ... | Authors: | Bailey, J.B, Zhang, L, Chiong, J.C, Ahn, S, Tezcan, F.A. | Deposit date: | 2017-02-01 | Release date: | 2017-06-21 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.631 Å) | Cite: | Synthetic Modularity of Protein-Metal-Organic Frameworks. J. Am. Chem. Soc., 139, 2017
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