2CWO
 
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3UAI
 | | Structure of the Shq1-Cbf5-Nop10-Gar1 complex from Saccharomyces cerevisiae | | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 3, H/ACA ribonucleoprotein complex subunit 4, ... | | Authors: | Ye, K. | | Deposit date: | 2011-10-21 | | Release date: | 2011-12-14 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.06 Å) | | Cite: | Structure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenita
Embo J., 30, 2011
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3U28
 | | Crystal structure of a Cbf5-Nop10-Gar1 complex from Saccharomyces cerevisiae | | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 3, H/ACA ribonucleoprotein complex subunit 4 | | Authors: | Ye, K, Li, S. | | Deposit date: | 2011-10-02 | | Release date: | 2011-12-14 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase
Genes Dev., 25, 2011
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3UAH
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5LU8
 | | CRYSTAL STRUCTURE OF YVAD-CMK BOUND HUMAN LEGUMAIN (AEP) IN COMPLEX WITH COMPOUND 11B | | Descriptor: | 2,4-di(morpholin-4-yl)aniline, 2-acetamido-2-deoxy-beta-D-glucopyranose, AC-TYR-VAL-ALA-ASP-CHLOROMETHYLKETONE, ... | | Authors: | Dall, E, Ye, K, Brandstetter, H. | | Deposit date: | 2016-09-08 | | Release date: | 2017-03-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.
Nat Commun, 8, 2017
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4JDE
 | | Crystal structure of PUD-1/PUD-2 heterodimer | | Descriptor: | CHLORIDE ION, GLYCEROL, Protein F15E11.1, ... | | Authors: | Luo, S, Ye, K. | | Deposit date: | 2013-02-25 | | Release date: | 2013-11-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Characterization of PUD-1 and PUD-2, two proteins up-regulated in a long-lived daf-2 mutant.
Plos One, 8, 2013
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3PLA
 | | Crystal structure of a catalytically active substrate-bound box C/D RNP from Sulfolobus solfataricus | | Descriptor: | 50S ribosomal protein L7Ae, C/D guide RNA, Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, ... | | Authors: | Lin, J, Lai, S, Jia, R, Xu, A, Zhang, L, Lu, J, Ye, K. | | Deposit date: | 2010-11-15 | | Release date: | 2011-01-26 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Structural basis for site-specific ribose methylation by box C/D RNA protein complexes.
Nature, 469, 2011
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3TBO
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3TBN
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3TBM
 | | Crystal structure of a type 4 CDGSH iron-sulfur protein. | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, L(+)-TARTARIC ACID, NONAETHYLENE GLYCOL, ... | | Authors: | Lin, J, Zhang, L, Ye, K. | | Deposit date: | 2011-08-07 | | Release date: | 2011-10-05 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.797 Å) | | Cite: | Structure and Molecular Evolution of CDGSH Iron-Sulfur Domains.
Plos One, 6, 2011
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5LUA
 | | Crystal structure of human legumain (AEP) in complex with compound 11b | | Descriptor: | 2,4-di(morpholin-4-yl)aniline, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Dall, E, Ye, K, Brandstetter, H. | | Deposit date: | 2016-09-08 | | Release date: | 2017-03-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.
Nat Commun, 8, 2017
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5LUB
 | | Crystal structure of human legumain (AEP) in complex with compound 11 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-(morpholin-4-yl)-2,1,3-benzoxadiazol-4-amine, ... | | Authors: | Dall, E, Ye, K, Brandstetter, H. | | Deposit date: | 2016-09-08 | | Release date: | 2017-03-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.
Nat Commun, 8, 2017
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5LU9
 | | Crystal structure of YVAD-cmk bound human legumain (AEP) in complex with compound 11 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-(morpholin-4-yl)-2,1,3-benzoxadiazol-4-amine, AC-TYR-VAL-ALA-ASP-CHLOROMETHYLKETONE, ... | | Authors: | Dall, E, Ye, K, Brandstetter, H. | | Deposit date: | 2016-09-08 | | Release date: | 2017-03-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.
Nat Commun, 8, 2017
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4J0X
 | | Structure of Rrp9 | | Descriptor: | Ribosomal RNA-processing protein 9 | | Authors: | Zhang, L, Lin, J, Ye, K. | | Deposit date: | 2013-01-31 | | Release date: | 2013-06-05 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Structural and functional analysis of the U3 snoRNA binding protein Rrp9.
Rna, 19, 2013
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4J0W
 | | Structure of U3-55K | | Descriptor: | U3 small nucleolar RNA-interacting protein 2 | | Authors: | Zhang, L, Lin, J, Ye, K. | | Deposit date: | 2013-01-31 | | Release date: | 2013-06-05 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural and functional analysis of the U3 snoRNA binding protein Rrp9.
Rna, 19, 2013
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6SES
 | | Tubulin-B2 complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Guo, B, Rodriguez-Gabin, A, Prota, A.E, Muehlethaler, T, Zhang, N, Ye, K, Steinmetz, M.O, Band Horwitz, S, Smith III, A.B, McDaid, H.M. | | Deposit date: | 2019-07-30 | | Release date: | 2020-07-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence.
Mol.Pharmacol., 98, 2020
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4M5D
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4MJ7
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4WNZ
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5YAX
 | | Crystal structure of a human neutralizing antibody bound to a HBV preS1 peptide | | Descriptor: | Large envelope protein, SODIUM ION, scFv1 antibody | | Authors: | Liu, X, Zheng, S, Ye, K, Sui, J. | | Deposit date: | 2017-09-02 | | Release date: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A potent human neutralizing antibody Fc-dependently reduces established HBV infections
Elife, 6, 2017
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4NSX
 | | Crystal Structure of the Utp21 tandem WD Domain | | Descriptor: | CITRATE ANION, U3 small nucleolar RNA-associated protein 21 | | Authors: | Zhang, C, Ye, K. | | Deposit date: | 2013-11-29 | | Release date: | 2014-02-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of Utp21 Tandem WD Domain Provides Insight into the Organization of the UTPB Complex Involved in Ribosome Synthesis
Plos One, 9, 2014
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6IF4
 | | Crystal structure of Tbtudor | | Descriptor: | Histone acetyltransferase | | Authors: | Gao, J, Ye, K, Diwu, Y, Liao, S, Tu, X. | | Deposit date: | 2018-09-18 | | Release date: | 2019-09-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.934 Å) | | Cite: | Crystal structure of TbEsa1 presumed Tudor domain from Trypanosoma brucei.
J.Struct.Biol., 209, 2020
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4QMF
 | | Structure of the Krr1 and Faf1 complex from Saccharomyces cerevisiae | | Descriptor: | KRR1 small subunit processome component, Protein FAF1 | | Authors: | Zheng, S, Ye, K. | | Deposit date: | 2014-06-16 | | Release date: | 2014-07-09 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.804 Å) | | Cite: | Interaction between ribosome assembly factors Krr1 and Faf1 is essential for formation of small ribosomal subunit in yeast
J.Biol.Chem., 289, 2014
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4RKG
 | | Structure of the MSL2 CXC domain bound with a non-specific (GC)6 DNA | | Descriptor: | DNA (5'-D(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*C)-3'), E3 ubiquitin-protein ligase msl-2, ZINC ION | | Authors: | Zheng, S, Ye, K. | | Deposit date: | 2014-10-13 | | Release date: | 2015-01-21 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation.
Genes Dev., 28, 2014
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4RKH
 | | Structure of the MSL2 CXC domain bound with a specific MRE sequence | | Descriptor: | DNA (5'-D(*AP*TP*CP*CP*AP*TP*CP*TP*CP*GP*CP*TP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*GP*AP*GP*CP*GP*AP*GP*AP*TP*GP*GP*AP*T)-3'), E3 ubiquitin-protein ligase msl-2, ... | | Authors: | Zheng, S, Ye, K. | | Deposit date: | 2014-10-13 | | Release date: | 2015-01-21 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation.
Genes Dev., 28, 2014
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