6JIA
| Marine bacterial laminarinase mutant E135A complex with laminaritetraose | Descriptor: | CALCIUM ION, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-alpha-D-glucopyranose, laminarinase | Authors: | Yang, J, Xu, Y, Miyakawa, T, Tanokura, M, Long, L. | Deposit date: | 2019-02-20 | Release date: | 2019-05-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular Basis for Substrate Recognition and Catalysis by a Marine Bacterial Laminarinase. Appl.Environ.Microbiol., 86, 2020
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7EDX
| p53-bound TFIID-based core PIC on HDM2 promoter | Descriptor: | DNA (84-mer), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | Deposit date: | 2021-03-17 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EG7
| TFIID-based core PIC on SCP promoter | Descriptor: | DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGA
| TFIID-based intermediate PIC on PUMA promoter | Descriptor: | DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EG9
| TFIID-based intermediate PIC on SCP promoter | Descriptor: | DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Qi, Y, Wang, X, Wu, Z, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EG8
| TFIID-based core PIC on PUMA promoter | Descriptor: | DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (7.4 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGH
| TFIID lobe C subcomplex | Descriptor: | DNA (45-MER), Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGD
| SCP promoter-bound TFIID-TFIIA in initial TBP-loading state | Descriptor: | DNA (72-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (6.75 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGJ
| SCP promoter-bound TFIID-TFIIA in post TBP-loading state | Descriptor: | DNA (74-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (8.64 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGC
| p53-bound TFIID-based holo PIC on HDM2 promoter | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7ENA
| TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. | Deposit date: | 2021-04-16 | Release date: | 2021-05-26 | Last modified: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (4.07 Å) | Cite: | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
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7ENC
| TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. | Deposit date: | 2021-04-16 | Release date: | 2021-05-26 | Last modified: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (4.13 Å) | Cite: | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
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7YCX
| The structure of INTAC-PEC complex | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y. | Deposit date: | 2022-07-02 | Release date: | 2023-03-15 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Structural basis of INTAC-regulated transcription. Protein Cell, 14, 2023
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6JHJ
| Structure of Marine bacterial laminarinase mutant-E135A | Descriptor: | CALCIUM ION, LamCAT | Authors: | Yang, J, Xu, Y, Miyakawa, T, Tanokura, M, Long, L. | Deposit date: | 2019-02-18 | Release date: | 2019-04-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Molecular Basis for Substrate Recognition and Catalysis by a Marine Bacterial Laminarinase. Appl.Environ.Microbiol., 86, 2020
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1VRY
| Second and Third Transmembrane Domains of the Alpha-1 Subunit of Human Glycine Receptor | Descriptor: | Glycine receptor alpha-1 chain | Authors: | Ma, D, Liu, Z, Li, L, Tang, P, Xu, Y. | Deposit date: | 2005-07-20 | Release date: | 2005-07-26 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure and Dynamics of the Second and Third Transmembrane Domains of Human Glycine Receptor. Biochemistry, 44, 2005
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2KZ1
| Inter-molecular interactions in a 44 kDa interferon-receptor complex detected by asymmetric back-protonation and 2D NOESY | Descriptor: | Interferon alpha-2, Soluble IFN alpha/beta receptor | Authors: | Nudelman, I, Akabayov, S.R, Schnur, E, Biron, Z, Levy, R, Xu, Y, Yang, D, Anglister, J. | Deposit date: | 2010-06-10 | Release date: | 2010-06-23 | Last modified: | 2021-08-18 | Method: | SOLUTION NMR | Cite: | Intermolecular interactions in a 44 kDa interferon-receptor complex detected by asymmetric reverse-protonation and two-dimensional NOESY Biochemistry, 49, 2010
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2LLY
| NMR structures of the transmembrane domains of the nAChR a4 subunit | Descriptor: | Neuronal acetylcholine receptor subunit alpha-4 | Authors: | Bondarenko, V, Mowrey, D, Tillman, T, Cui, T, Liu, L.T, Xu, Y, Tang, P. | Deposit date: | 2011-11-18 | Release date: | 2012-03-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR structures of the transmembrane domains of the a4b2 nAChR. Biochim.Biophys.Acta, 1818, 2012
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2LM2
| NMR structures of the transmembrane domains of the AChR b2 subunit | Descriptor: | Neuronal acetylcholine receptor subunit beta-2 | Authors: | Bondarenko, V, Mowrey, D, Tillman, T, Cui, T, Liu, L.T, Xu, Y, Tang, P. | Deposit date: | 2011-11-18 | Release date: | 2012-03-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR structures of the transmembrane domains of the a4b2 nAChR. Biochim.Biophys.Acta, 1818, 2012
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2MAW
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7DPV
| SARS-CoV-2 3CL protease (3CLpro) in complex with 7-O-methyl-dihydromyricetin | Descriptor: | (2S,3S)-3,5-dihydroxy-7-methoxy-2-(3,4,5-trihydroxyphenyl)chroman-4-one, 3C-like proteinase | Authors: | Su, H.X, Zhao, W.F, Xie, H, Li, M.J, Xu, Y.C. | Deposit date: | 2020-12-21 | Release date: | 2021-05-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease. Nat Commun, 12, 2021
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7DPP
| SARS-CoV-2 3CL protease (3CLpro) in complex with myricetin | Descriptor: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, 3C-like proteinase | Authors: | Su, H.X, Zhao, W.F, Xie, H, Li, M.J, Xu, Y.C. | Deposit date: | 2020-12-21 | Release date: | 2021-05-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease. Nat Commun, 12, 2021
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2NBA
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2N59
| Solution Structure of R. palustris CsgH | Descriptor: | Putative uncharacterized protein CsgH | Authors: | Hawthorne, W.J, Taylor, J.D, Escalera-Maurer, A, Lambert, S, Koch, M, Scull, N, Sefer, L, Xu, Y, Matthews, S.J. | Deposit date: | 2015-07-13 | Release date: | 2016-05-11 | Method: | SOLUTION NMR | Cite: | Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones. Sci Rep, 6, 2016
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2MC5
| A bacteriophage transcription regulator inhibits bacterial transcription initiation by -factor displacement | Descriptor: | 45L | Authors: | Liu, B, Shadrin, A, Sheppard, C, Xu, Y, Severinov, K, Matthews, S, Wigneshweraraj, S. | Deposit date: | 2013-08-14 | Release date: | 2014-03-26 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement. Nucleic Acids Res., 42, 2014
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2MC6
| A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement | Descriptor: | DNA-directed RNA polymerase subunit beta', RNA polymerase inhibitor p7 | Authors: | Liu, B, Shadrin, A, Sheppard, C, Xu, Y, Severinov, K, Matthews, S, Wigneshweraraj, S. | Deposit date: | 2013-08-15 | Release date: | 2014-04-02 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement. Nucleic Acids Res., 42, 2014
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