4V6I
 
 | | Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome | | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein RACK1 (RACK1), ... | | Authors: | Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. | | Deposit date: | 2010-10-12 | | Release date: | 2014-07-09 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (8.8 Å) | | Cite: | Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
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1RMN
 | | A THREE-DIMENSIONAL MODEL FOR THE HAMMERHEAD RIBOZYME BASED ON FLUORESCENCE MEASUREMENTS | | Descriptor: | RNA (49-MER) | | Authors: | Tuschl, T, Gohlke, C, Jovin, T.M, Westhof, E, Eckstein, F. | | Deposit date: | 1994-10-20 | | Release date: | 1995-01-26 | | Last modified: | 2024-02-14 | | Method: | FLUORESCENCE TRANSFER | | Cite: | A three-dimensional model for the hammerhead ribozyme based on fluorescence measurements.
Science, 266, 1994
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1FQZ
 | | NMR VALIDATED MODEL OF DOMAIN IIID OF HEPATITIS C VIRUS INTERNAL RIBOSOME ENTRY SITE | | Descriptor: | HEPATITIS C VIRUS IRES DOMAIN IIID | | Authors: | Klinck, R, Westhof, E, Walker, S, Afshar, M, Collier, A, Aboul-ela, F. | | Deposit date: | 2000-09-07 | | Release date: | 2001-01-17 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | A potential RNA drug target in the hepatitis C virus internal ribosomal entry site.
RNA, 6, 2000
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1J7T
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2WWA
 | | Cryo-EM structure of idle yeast Ssh1 complex bound to the yeast 80S ribosome | | Descriptor: | 25S RRNA, 60S RIBOSOMAL PROTEIN L17-A, 60S RIBOSOMAL PROTEIN L19, ... | | Authors: | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | | Deposit date: | 2009-10-22 | | Release date: | 2009-12-08 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (8.9 Å) | | Cite: | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome.
Science, 326, 2009
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2WWB
 | | CRYO-EM STRUCTURE OF THE MAMMALIAN SEC61 COMPLEX BOUND TO THE ACTIVELY TRANSLATING WHEAT GERM 80S RIBOSOME | | Descriptor: | 25S RRNA, 5.8S RRNA, 60S RIBOSOMAL PROTEIN L17-A, ... | | Authors: | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | | Deposit date: | 2009-10-22 | | Release date: | 2009-12-08 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.48 Å) | | Cite: | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome.
Science, 326, 2009
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2WW9
 | | Cryo-EM structure of the active yeast Ssh1 complex bound to the yeast 80S ribosome | | Descriptor: | 25S RRNA, 60S RIBOSOMAL PROTEIN L17-A, 60S RIBOSOMAL PROTEIN L19, ... | | Authors: | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | | Deposit date: | 2009-10-22 | | Release date: | 2009-12-08 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (8.6 Å) | | Cite: | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome.
Science, 326, 2009
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1LC4
 | | Crystal Structure of Tobramycin Bound to the Eubacterial 16S rRNA A Site | | Descriptor: | 5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', TOBRAMYCIN | | Authors: | Vicens, Q, Westhof, E. | | Deposit date: | 2002-04-05 | | Release date: | 2003-04-08 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | Crystal Structure of a Complex between the Aminoglycoside Tobramycin and an
Oligonucleotide Containing the Ribosomal Decoding A Site
Chem.Biol., 9, 2002
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4V7E
 | | Model of the small subunit RNA based on a 5.5 A cryo-EM map of Triticum aestivum translating 80S ribosome | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S10E, ... | | Authors: | Barrio-Garcia, C, Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. | | Deposit date: | 2013-11-22 | | Release date: | 2014-07-09 | | Last modified: | 2023-02-01 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion.
Nature, 506, 2014
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6GYV
 | | Lariat-capping ribozyme (circular permutation form) | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Lariat-capping ribozyme, MAGNESIUM ION, ... | | Authors: | Masquida, B, Meyer, M, Nielsen, H, Olieric, V, Roblin, P, Johansen, S.D, Westhof, E. | | Deposit date: | 2018-07-02 | | Release date: | 2018-08-22 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.50003624 Å) | | Cite: | Speciation of a group I intron into a lariat capping ribozyme.
Proc. Natl. Acad. Sci. U.S.A., 111, 2014
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1KOC
 | | RNA APTAMER COMPLEXED WITH ARGININE, NMR | | Descriptor: | ARGININE, RNA (5'-R(P*AP*CP*AP*GP*GP*UP*AP*GP*GP*UP*CP*GP*CP*U)-3'), RNA (5'-R(P*AP*GP*AP*AP*GP*GP*AP*GP*CP*GP*U)-3') | | Authors: | Yang, Y.S, Kochoyan, M, Burgstaller, P, Westhof, E, Famulok, M. | | Deposit date: | 1996-03-28 | | Release date: | 1996-08-17 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Structural basis of ligand discrimination by two related RNA aptamers resolved by NMR spectroscopy.
Science, 272, 1996
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1KOD
 | | RNA APTAMER COMPLEXED WITH CITRULLINE, NMR | | Descriptor: | CITRULLINE, RNA (5'-R(P*AP*CP*GP*GP*UP*UP*AP*GP*GP*UP*CP*GP*CP*U)-3'), RNA (5'-R(P*AP*GP*AP*AP*GP*GP*AP*GP*UP*GP*U)-3') | | Authors: | Yang, Y.S, Kochoyan, M, Burgstaller, P, Westhof, E, Famulok, M. | | Deposit date: | 1996-03-28 | | Release date: | 1996-11-08 | | Last modified: | 2023-11-15 | | Method: | SOLUTION NMR | | Cite: | Structural basis of ligand discrimination by two related RNA aptamers resolved by NMR spectroscopy.
Science, 272, 1996
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4P20
 | | Crystal structures of the bacterial ribosomal decoding site complexed with amikacin | | Descriptor: | (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, 5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3' | | Authors: | Kondo, J, Francois, B, Russell, R.J.M, Murray, J.B, Westhof, E. | | Deposit date: | 2014-02-28 | | Release date: | 2014-05-07 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of the bacterial ribosomal decoding site complexed with amikacin containing the gamma-amino-alpha-hydroxybutyryl (haba) group.
Biochimie, 88, 2006
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4P9R
 | | Speciation of a group I intron into a lariat capping ribozyme (Heavy atom derivative) | | Descriptor: | IRIDIUM HEXAMMINE ION, MAGNESIUM ION, RNA (189-MER) | | Authors: | Meyer, M, Nielsen, H, Olieric, V, Roblin, P, Johansen, S.D, Westhof, E, Masquida, B. | | Deposit date: | 2014-04-04 | | Release date: | 2014-05-28 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.703 Å) | | Cite: | Speciation of a group I intron into a lariat capping ribozyme.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4P8Z
 | | Speciation of a group I intron into a lariat capping ribozyme | | Descriptor: | Didymium iridis partial IGS, 18S rRNA gene, I-DirI gene and partial ITS1 | | Authors: | Meyer, M, Nielsen, H, Olieric, V, Roblin, P, Johansen, S.D, Westhof, E, Masquida, B. | | Deposit date: | 2014-04-01 | | Release date: | 2014-05-28 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.85 Å) | | Cite: | Speciation of a group I intron into a lariat capping ribozyme.
Proc.Natl.Acad.Sci.USA, 111, 2014
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2NOQ
 | | Structure of ribosome-bound cricket paralysis virus IRES RNA | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S5, ... | | Authors: | Schuler, M, Connell, S.R, Lescoute, A, Giesebrecht, J, Dabrowski, M, Schroeer, B, Mielke, T, Penczek, P.A, Westhof, E, Spahn, C.M.T. | | Deposit date: | 2006-10-26 | | Release date: | 2006-11-21 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (7.3 Å) | | Cite: | Structure of the ribosome-bound cricket paralysis virus IRES RNA.
Nat.Struct.Mol.Biol., 13, 2006
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2O3X
 | | Crystal Structure of the Prokaryotic Ribosomal Decoding Site Complexed with Paromamine Derivative NB30 | | Descriptor: | (1R,2R,3S,4R,6S)-4,6-DIAMINO-2-[(5-AMINO-5-DEOXY-BETA-D-RIBOFURANOSYL)OXY]-3-HYDROXYCYCLOHEXYL 2-AMINO-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3') | | Authors: | Kondo, J, Hainrichson, M, Nudelman, I, Shallom-Shezifi, D, Baasov, T, Westhof, E. | | Deposit date: | 2006-12-02 | | Release date: | 2007-11-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites.
Chembiochem, 8, 2007
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2O3V
 | | Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site complexed with paromamine derivative NB33 | | Descriptor: | (2S,3R,4R,5S,6R)-3-AMINO-4-({[(2S,3R,4R,5S,6R)-3-AMINO-2-{[(1R,2R,3S,4R,6S)-4,6-DIAMINO-2,3-DIHYDROXYCYCLOHEXYL]OXY}-5-HYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-4-YL]OXY}METHOXY)-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2,5-DIOL, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3') | | Authors: | Kondo, J, Hainrichson, M, Nudelman, I, Shallom-Shezifi, D, Baasov, T, Westhof, E. | | Deposit date: | 2006-12-02 | | Release date: | 2007-11-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites.
Chembiochem, 8, 2007
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2O3W
 | | Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site in presence of paromomycin | | Descriptor: | PAROMOMYCIN, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3') | | Authors: | Kondo, J, Hainrichson, M, Nudelman, I, Shallom-Shezifi, D, Baasov, T, Westhof, E. | | Deposit date: | 2006-12-02 | | Release date: | 2007-11-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites.
Chembiochem, 8, 2007
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2O3Y
 | | Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site in Presence of Paromamine Derivative NB30 | | Descriptor: | RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3'), SPERMINE | | Authors: | Kondo, J, Hainrichson, M, Nudelman, I, Shallom-Shezifi, D, Baasov, T, Westhof, E. | | Deposit date: | 2006-12-02 | | Release date: | 2007-11-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites.
Chembiochem, 8, 2007
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2PWT
 | | Crystal structure of the bacterial ribosomal decoding site complexed with aminoglycoside containing the L-HABA group | | Descriptor: | 22-mer of the ribosomal decoding site, DOUBLY FUNCTIONALIZED PAROMOMYCIN PM-II-162 | | Authors: | Kondo, J, Pachamuthu, K, Francois, B, Szychowski, J, Hanessian, S, Westhof, E. | | Deposit date: | 2007-05-13 | | Release date: | 2007-09-18 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of the Bacterial Ribosomal Decoding Site Complexed with a Synthetic Doubly Functionalized Paromomycin Derivative: a New Specific Binding Mode to an A-Minor Motif Enhances in vitro Antibacterial Activity
Chemmedchem, 2, 2007
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5J02
 | | Structure of the lariat form of a chimeric derivative of the Oceanobacillus iheyensis group II intron in the presence of NH4+, MG2+ and an inactive 5' exon. | | Descriptor: | 5' EXON ANALOG (5'-R(*CP*UP*GP*UP*UP*AP*(5MU))-3'), AMMONIUM ION, GROUP II INTRON LARIAT, ... | | Authors: | Costa, M, Walbott, H, Monachello, D, Westhof, E, Michel, F. | | Deposit date: | 2016-03-26 | | Release date: | 2016-12-14 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.493 Å) | | Cite: | Crystal structures of a group II intron lariat primed for reverse splicing.
Science, 354, 2016
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5J01
 | | Structure of the lariat form of a chimeric derivative of the Oceanobacillus iheyensis group II intron in the presence of NH4+ and MG2+. | | Descriptor: | AMMONIUM ION, MAGNESIUM ION, group II intron lariat | | Authors: | Costa, M, Walbott, H, Monachello, D, Westhof, E, Michel, F. | | Deposit date: | 2016-03-26 | | Release date: | 2016-12-14 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.39 Å) | | Cite: | Crystal structures of a group II intron lariat primed for reverse splicing.
Science, 354, 2016
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3BNP
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3BNT
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