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PDB: 236 results
6U02
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BU of 6u02 by Molmil
CryoEM-derived model of NA-63 Fab in complex with N9 Shanghai2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab-63 Heavy Chain, Fab-63 Light Chain, ...
Authors:Ward, A.B, Turner, H.L, Zhu, X.
Deposit date:2019-08-13
Release date:2019-12-04
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6VL5
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BU of 6vl5 by Molmil
BG505 SOSIP reconstructed from a designed tetrahedral nanoparticle, BG505 SOSIP-T33_dn2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ...
Authors:Ward, A.B, Antanasijevic, A.
Deposit date:2020-01-22
Release date:2020-08-12
Last modified:2020-09-02
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations.
NPJ Vaccines, 5, 2020
6VL6
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BU of 6vl6 by Molmil
De novo designed tetrahedral nanoparticle T33_dn2 presenting BG505 SOSIP trimers
Descriptor: T33_dn2A, T33_dn2B
Authors:Ward, A.B, Antanasijevic, A.
Deposit date:2020-01-22
Release date:2020-08-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations.
NPJ Vaccines, 5, 2020
6PCI
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BU of 6pci by Molmil
EBOV GPdMuc (Makona) in complex with rEBOV-520 and rEBOV-548 Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Virion spike glycoprotein, Virion spike glycoprotein,Virion spike glycoprotein,Ebola Virus (Makona) GP2, ...
Authors:Ward, A.B, Murin, C.D, Alkutkar, T.
Deposit date:2019-06-17
Release date:2020-03-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.12 Å)
Cite:Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Immunity, 52, 2020
6PZW
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BU of 6pzw by Molmil
CryoEM derived model of NA-22 Fab in complex with N9 Shanghai2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NA-22 fragment antigen binding heavy chain, ...
Authors:Ward, A.B, Turner, H.L, Zhu, X.
Deposit date:2019-08-01
Release date:2019-12-04
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6PZZ
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BU of 6pzz by Molmil
CryoEM derived model of NA-80 Fab in complex with N9 Shanghai2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NA-80 fragment antibody heavy chain, ...
Authors:Ward, A.B, Turner, H.L, Zhu, X.
Deposit date:2019-08-01
Release date:2019-12-04
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6PZY
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BU of 6pzy by Molmil
CryoEM derived model of NA-73 Fab in complex with N9 Shanghai2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NA-73 fragment antibody heavy chain, ...
Authors:Ward, A.B, Turner, H.L, Zhu, X.
Deposit date:2019-08-01
Release date:2019-12-04
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
3J5M
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BU of 3j5m by Molmil
Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs
Descriptor: BG505 SOSIP gp120, BG505 SOSIP gp41, PGV04 heavy chain, ...
Authors:Lyumkis, D, Julien, J.-P, Wilson, I.A, Ward, A.B.
Deposit date:2013-10-26
Release date:2013-11-13
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
6X96
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BU of 6x96 by Molmil
Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 10A fragment antigen binding variable domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 HIV-1 Env gp120, ...
Authors:Ozorowski, G, Cottrell, C.A, Ward, A.B.
Deposit date:2020-06-02
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions
To Be Published
6X97
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BU of 6x97 by Molmil
Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 11A fragment antigen binding variable domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 HIV-1 Env gp120, ...
Authors:Ozorowski, G, Cottrell, C.A, Ward, A.B.
Deposit date:2020-06-02
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions
To Be Published
6X98
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BU of 6x98 by Molmil
Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 11B fragment antigen binding variable domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 HIV-1 Env gp120, ...
Authors:Ozorowski, G, Cottrell, C.A, Ward, A.B.
Deposit date:2020-06-02
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions
To Be Published
7M8L
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BU of 7m8l by Molmil
EBOV GP bound to rEBOV-442 and rEBOV-515 Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Virion spike glycoprotein 1, ...
Authors:Murin, C.D, Ward, A.B.
Deposit date:2021-03-30
Release date:2021-11-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Pan-ebolavirus protective therapy by two multifunctional human antibodies.
Cell, 184, 2021
7MDU
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BU of 7mdu by Molmil
BG505 SOSIP MD39 in complex with the monoclonal antibodies Rh.33104 mAb.1 and RM20A3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RM20A3 mAb Heavy Chain, ...
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2021-04-06
Release date:2022-01-26
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:From structure to sequence: Antibody discovery using cryoEM.
Sci Adv, 8, 2022
7MDT
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BU of 7mdt by Molmil
BG505 SOSIP.v5.2 in complex with the monoclonal antibody Rh4O9.8 (as Fab fragment)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Rh4O9.8 monoclonal antibody Heavy Chain, ...
Authors:Antanasijevic, A, Ozorowski, G, Nogal, B, Ward, A.B.
Deposit date:2021-04-06
Release date:2022-01-26
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:From structure to sequence: Antibody discovery using cryoEM.
Sci Adv, 8, 2022
7MEP
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BU of 7mep by Molmil
BG505 SOSIP.v5.2(7S) in complex with the monoclonal antibodies Rh.33172 mAb.1 and RM19R
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIPv5.2(7S) - gp120, ...
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2021-04-07
Release date:2022-01-26
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:From structure to sequence: Antibody discovery using cryoEM.
Sci Adv, 8, 2022
7N5G
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BU of 7n5g by Molmil
Structure of Mechanosensitive Ion Channel Flycatcher1 Protomer in 'Up' conformation in GDN
Descriptor: Mechanosensitive ion channel Flycatcher1, PALMITIC ACID
Authors:Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B.
Deposit date:2021-06-05
Release date:2022-02-16
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1.
Nat Commun, 13, 2022
7N5E
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BU of 7n5e by Molmil
Structure of Mechanosensitive Ion Channel Flycatcher1 in GDN
Descriptor: Mechanosensitive ion channel Flycatcher1, PALMITIC ACID
Authors:Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B.
Deposit date:2021-06-05
Release date:2022-02-16
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1.
Nat Commun, 13, 2022
7N5D
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BU of 7n5d by Molmil
Composite Structure of Mechanosensitive Ion Channel Flycatcher1 in GDN
Descriptor: Mechanosensitive ion channel Flycatcher1, PALMITIC ACID
Authors:Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B.
Deposit date:2021-06-05
Release date:2022-02-16
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1.
Nat Commun, 13, 2022
7N5F
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BU of 7n5f by Molmil
Structure of Mechanosensitive Ion Channel Flycatcher1 Protomer in 'Down' conformation in GDN
Descriptor: Mechanosensitive ion channel Flycatcher1, PALMITIC ACID
Authors:Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B.
Deposit date:2021-06-05
Release date:2022-02-16
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1.
Nat Commun, 13, 2022
5VYH
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BU of 5vyh by Molmil
Crystal Structure of MERS-CoV S1 N-terminal Domain
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
Authors:Wang, N, Wrapp, D, Pallesen, J, Ward, A.B, McLellan, J.S.
Deposit date:2017-05-25
Release date:2017-08-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9J
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BU of 5w9j by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: G4 VH, G4 VL, Spike glycoprotein
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9P
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BU of 5w9p by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: G4 VH, G4 VL, Spike glycoprotein
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9M
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BU of 5w9m by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: G4 VH, G4 VL, Spike glycoprotein
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9O
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BU of 5w9o by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: G4 VH, G4 VL, Spike glycoprotein
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9I
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BU of 5w9i by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, G4 VH, ...
Authors:Pallesen, J, Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

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