3ULX
 
 | |
6M71
 | | SARS-Cov-2 RNA-dependent RNA polymerase in complex with cofactors | | Descriptor: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase | | Authors: | Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z. | | Deposit date: | 2020-03-16 | | Release date: | 2020-04-01 | | Last modified: | 2021-03-10 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Science, 368, 2020
|
|
7BOK
 | | Cryo-EM structure of the encapsulated DyP-type peroxidase from Mycobacterium smegmatis | | Descriptor: | Dyp-type peroxidase, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Tang, Y.T, Mu, A, Gong, H.R, Wang, Q, Rao, Z.H. | | Deposit date: | 2020-03-19 | | Release date: | 2021-03-24 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cryo-EM structure of Mycobacterium smegmatis DyP-loaded encapsulin.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7BOJ
 | | Cryo-EM structure of the encapsulin shell from Mycobacterium smegmatis | | Descriptor: | 29 kDa antigen Cfp29 | | Authors: | Tang, Y.T, Mu, A, Gong, H.R, Wang, Q, Rao, Z.H. | | Deposit date: | 2020-03-19 | | Release date: | 2021-03-24 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Cryo-EM structure of Mycobacterium smegmatis DyP-loaded encapsulin.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7RPK
 | | Cryo-EM structure of murine Dispatched in complex with Sonic hedgehog | | Descriptor: | (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | | Deposit date: | 2021-08-03 | | Release date: | 2021-10-27 | | Last modified: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
|
|
7RPI
 | | Cryo-EM structure of murine Dispatched 'T' conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Lauryl Maltose Neopentyl Glycol, ... | | Authors: | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | | Deposit date: | 2021-08-03 | | Release date: | 2021-10-27 | | Last modified: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
|
|
7RPH
 | | Cryo-EM structure of murine Dispatched 'R' conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Lauryl Maltose Neopentyl Glycol, ... | | Authors: | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | | Deposit date: | 2021-08-03 | | Release date: | 2021-10-27 | | Last modified: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
|
|
7RPJ
 | | Cryo-EM structure of murine Dispatched NNN mutant | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1 | | Authors: | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | | Deposit date: | 2021-08-03 | | Release date: | 2021-10-27 | | Last modified: | 2021-11-24 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
|
|
3DP4
 | | Crystal structure of the binding domain of the AMPA subunit GluR3 bound to AMPA | | Descriptor: | (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 3, ZINC ION | | Authors: | Ahmed, A.H, Wang, Q, Sondermann, H, Oswald, R.E. | | Deposit date: | 2008-07-07 | | Release date: | 2008-11-25 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Structure of the S1S2 glutamate binding domain of GLuR3.
Proteins, 75, 2008
|
|
3DP6
 | | Crystal structure of the binding domain of the AMPA subunit GluR2 bound to glutamate | | Descriptor: | GLUTAMIC ACID, Glutamate receptor 2, ZINC ION | | Authors: | Ahmed, A.H, Wang, Q, Sondermann, H, Oswald, R.E. | | Deposit date: | 2008-07-07 | | Release date: | 2008-11-25 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structure of the S1S2 glutamate binding domain of GLuR3.
Proteins, 75, 2008
|
|
3DLN
 | | Crystal structure of the binding domain of the AMPA subunit GluR3 bound to glutamate | | Descriptor: | GLUTAMIC ACID, Glutamate receptor 3, ZINC ION | | Authors: | Ahmed, A.H, Wang, Q, Sondermann, H, Oswald, R.E. | | Deposit date: | 2008-06-27 | | Release date: | 2008-11-25 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Structure of the S1S2 glutamate binding domain of GLuR3.
Proteins, 75, 2008
|
|
7U4M
 | | Crystal structure of human GPX4-U46C in complex with LOC1886 | | Descriptor: | 1,2-ETHANEDIOL, 4-methoxy-1H-indole-2-carbaldehyde, Phospholipid hydroperoxide glutathione peroxidase | | Authors: | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | Deposit date: | 2022-02-28 | | Release date: | 2022-12-07 | | Last modified: | 2022-12-28 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
|
|
7U4K
 | | Crystal structure of human GPX4-U46C-R152H in complex with ML162 | | Descriptor: | 1,2-ETHANEDIOL, 2-chloro-N-(3-chloro-4-methoxyphenyl)-N-[(1R)-2-oxo-2-[(2-phenylethyl)amino]-1-(thiophen-2-yl)ethyl]acetamide, Phospholipid hydroperoxide glutathione peroxidase | | Authors: | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Xia, X, Soni, R.K, Stockwell, B.R. | | Deposit date: | 2022-02-28 | | Release date: | 2022-12-07 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
|
|
7U4J
 | | Crystal structure of human GPX4-U46C-R152H in complex with TMT10 | | Descriptor: | Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION, ~{N}-(3-chloranyl-4-methoxy-phenyl)ethanamide | | Authors: | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | Deposit date: | 2022-02-28 | | Release date: | 2022-12-07 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
|
|
7U4I
 | | Crystal structure of human GPX4-U46C-R152H in complex with CDS9 | | Descriptor: | 2-bromo-N-[(thiophen-2-yl)methyl]acetamide, Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION | | Authors: | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | Deposit date: | 2022-02-28 | | Release date: | 2022-12-07 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
|
|
7U4N
 | | Crystal structure of human GPX4-U46C in complex with RSL3 | | Descriptor: | Phospholipid hydroperoxide glutathione peroxidase, methyl (1S,3R)-2-(chloroacetyl)-1-[4-(methoxycarbonyl)phenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate | | Authors: | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Xia, X, Soni, R.K, Stockwell, B.R. | | Deposit date: | 2022-02-28 | | Release date: | 2022-12-07 | | Last modified: | 2022-12-28 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
|
|
7U4L
 | | Crystal structure of human GPX4-U46C in complex with MAC-5576 | | Descriptor: | Phospholipid hydroperoxide glutathione peroxidase, thiophene-2-carbaldehyde | | Authors: | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | Deposit date: | 2022-02-28 | | Release date: | 2022-12-07 | | Last modified: | 2022-12-28 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
|
|
3FUS
 | | Improved Structure of the Unliganded Simian Immunodeficiency Virus gp120 Core | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Chen, X, Poon, B, Wang, Q, Ma, J. | | Deposit date: | 2009-01-14 | | Release date: | 2009-06-30 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structural improvement of unliganded simian immunodeficiency virus gp120 core by normal-mode-based X-ray crystallographic refinement.
Acta Crystallogr.,Sect.D, 65, 2009
|
|
3LUT
 | | A Structural Model for the Full-length Shaker Potassium Channel Kv1.2 | | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 2, ... | | Authors: | Chen, X, Ni, F, Wang, Q, Ma, J. | | Deposit date: | 2010-02-18 | | Release date: | 2010-06-23 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
4DUI
 | | DARPIN D1 binding to tubulin beta chain (not in complex) | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D1 | | Authors: | Pecqueur, L, Duellberg, C, Dreier, B, Wang, Q, Jiang, C, Pluckthun, A, Surrey, T, Gigant, B, Knossow, M. | | Deposit date: | 2012-02-22 | | Release date: | 2013-02-27 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.16 Å) | | Cite: | An Anti-Tubulin Darpin Caps the Microtubule Plus-End
To be Published
|
|
4E41
 | | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4 | | Descriptor: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... | | Authors: | Deng, L, Langley, R.J, Wang, Q, Topalian, S.L, Mariuzza, R.A. | | Deposit date: | 2012-03-11 | | Release date: | 2012-08-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
|
|
4E42
 | | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4 | | Descriptor: | CHLORIDE ION, NITRATE ION, SODIUM ION, ... | | Authors: | Deng, L, Langley, R.J, Wang, Q, Topalian, S.L, Mariuzza, R.A. | | Deposit date: | 2012-03-11 | | Release date: | 2012-08-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
|
|
7EN0
 | | Structure and Activity of SLAC1 Channels for Stomatal Signaling in Leaves | | Descriptor: | DIUNDECYL PHOSPHATIDYL CHOLINE, SLow Anion Channel 1, SPHINGOSINE | | Authors: | Deng, Y, Kashtoh, H, Wang, Q, Zhen, G, Li, Q, Tang, L, Gao, H, Zhang, C, Qin, L, Su, M, Li, F, Huang, X, Wang, Y, Xie, Q, Clarke, O.B, Hendrickson, W.A, Chen, Y. | | Deposit date: | 2021-04-15 | | Release date: | 2021-05-19 | | Method: | ELECTRON MICROSCOPY (2.97 Å) | | Cite: | Structure and activity of SLAC1 channels for stomatal signaling in leaves.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
5BR3
 | | Crystal structure of hemagglutinin of A/Taiwan/2/2013 (H6N1) in complex with LSTa | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, ... | | Authors: | Ni, F, Kondrashkina, E, Wang, Q. | | Deposit date: | 2015-05-29 | | Release date: | 2015-08-12 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural and Functional Studies of Influenza Virus A/H6 Hemagglutinin.
Plos One, 7, 2015
|
|
5BQZ
 | | Crystal structure of hemagglutinin of A/Chicken/Guangdong/S1311/2010 (H6N6) in complex with human-like receptor LSTc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ HA1 CHAIN, ... | | Authors: | Ni, F, Kondrashkina, E, Wang, Q. | | Deposit date: | 2015-05-29 | | Release date: | 2015-10-14 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Structural and Functional Studies of Influenza Virus A/H6 Hemagglutinin.
Plos One, 10, 2015
|
|
