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PDB: 10 results

2XA3
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crystal structure of the broadly neutralizing llama VHH D7 and its mode of HIV-1 gp120 interaction
Descriptor: LLAMA HEAVY CHAIN ANTIBODY D7, SULFATE ION
Authors:Hinz, A, Lutje Hulsik, D, Forsman, A, Koh, W, Belrhali, H, Gorlani, A, de Haard, H, Weiss, R.A, Verrips, T, Weissenhorn, W.
Deposit date:2010-03-29
Release date:2010-05-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the neutralizing Llama V(HH) D7 and its mode of HIV-1 gp120 interaction.
PLoS ONE, 5, 2010
3RJQ
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Crystal structure of anti-HIV llama VHH antibody A12 in complex with C186 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C186 gp120, Llama VHH A12
Authors:Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
Deposit date:2011-04-15
Release date:2012-05-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Crystal structure of anti-HIV A12 VHH of llama antibody in complex with C1086 gp120
To be Published
3R0M
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Crystal structure of anti-HIV llama VHH antibody A12
Descriptor: Llama VHH A12, SULFATE ION
Authors:Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
Deposit date:2011-03-08
Release date:2012-03-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Single-Headed Immunoglobulins Efficiently Penetrate CD4-Binding Site and Effectively Neutralize HIV-1
To be Published
1QD0
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CAMELID HEAVY CHAIN VARIABLE DOMAINS PROVIDE EFFICIENT COMBINING SITES TO HAPTENS
Descriptor: 3-HYDROXY-7-(4-{1-[2-HYDROXY-3-(2-HYDROXY-5-SULFO-PHENYLAZO)-BENZYL]-2-SULFO-ETHYLAMINO}-[1,2,5]TRIAZIN-2-YLAMINO)-2-(2-HYDROXY-5-SULFO-PHENYLAZO)-NAPTHALENE-1,8-DISULFONIC ACID, COPPER (II) ION, VHH-R2 ANTI-RR6 ANTIBODY
Authors:Spinelli, S, Frenken, L.G.J, Hermans, P, Verrips, T, Brown, K, Tegoni, M, Cambillau, C.
Deposit date:1999-07-08
Release date:2000-07-19
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Camelid heavy-chain variable domains provide efficient combining sites to haptens.
Biochemistry, 39, 2000
5O2U
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Llama VHH in complex with p24
Descriptor: Capsid protein p24, VHH 59H10
Authors:Caillat, C, Verrips, T, Weissenhorn, W.
Deposit date:2017-05-22
Release date:2017-06-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Unravelling the Molecular Basis of High Affinity Nanobodies against HIV p24: In Vitro Functional, Structural, and in Silico Insights.
ACS Infect Dis, 3, 2017
4R90
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Anti CD70 Llama glama Fab 27B3
Descriptor: Anti CD70 Llama glama Fab 27B3 Heavy chain, Anti CD70 Llama glama Fab 27B3 Light chain, CALCIUM ION, ...
Authors:Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I.
Deposit date:2014-09-03
Release date:2015-06-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.746 Å)
Cite:Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform.
MAbs, 7, 2015
4R96
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Structure of a Llama Glama Fab 48A2 against human cMet
Descriptor: Llama glama Fab 48A2 against human cMet H chain, Llama glama Fab 48A2 against human cMet L chain
Authors:Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I.
Deposit date:2014-09-03
Release date:2015-06-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform.
MAbs, 7, 2015
1U0Q
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Structure of a Llama VHH domain raised against a carbazole molecule
Descriptor: immunoglobulin heavy chain variable domain
Authors:Cambillau, C, Spinelli, S, Desmyter, A, Verrips, T.
Deposit date:2004-07-14
Release date:2005-06-28
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of a Llama VHH Domain Raised Against a Carbazole Hapten
TO BE PUBLISHED
1SJX
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Three-Dimensional Structure of a Llama VHH Domain OE7 binding the cell wall protein Malf1
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, immunoglobulin VH domain
Authors:Dolk, E, van der Vaart, M, Hulsik, D.L, Vriend, G, de Haard, H, Spinelli, S, Cambillau, C, Frenken, L, Verrips, T.
Deposit date:2004-03-04
Release date:2005-03-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Isolation of llama antibody fragments for prevention of dandruff by phage display in shampoo.
Appl.Environ.Microbiol., 71, 2005
1SJV
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Three-Dimensional Structure of a Llama VHH Domain Swapping
Descriptor: r9
Authors:Spinelli, S, Desmyter, A, Frenken, L, Verrips, T, Cambillau, C.
Deposit date:2004-03-04
Release date:2004-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Domain swapping of a llama VHH domain builds a crystal-wide beta-sheet structure.
Febs Lett., 564, 2004

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