4MU5
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![BU of 4mu5 by Molmil](/molmil-images/mine/4mu5) | Crystal structure of murine neuroglobin mutant M144W | Descriptor: | Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Vallone, B, Avella, G, Savino, C, Ardiccioni, C, Brunori, M. | Deposit date: | 2013-09-20 | Release date: | 2014-06-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Engineering the internal cavity of neuroglobin demonstrates the role of the haem-sliding mechanism. Acta Crystallogr.,Sect.D, 70, 2014
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1W92
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![BU of 1w92 by Molmil](/molmil-images/mine/1w92) | The structure of carbomonoxy murine neuroglobin reveals a heme- sliding mechanism for affinity regulation | Descriptor: | CARBON MONOXIDE, NEUROGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Vallone, B, Nienhaus, K, Matthes, A, Brunori, M, Nienhaus, G.U. | Deposit date: | 2004-10-05 | Release date: | 2004-11-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Structure of Carbonmonoxy Neuroglobin Reveals a Heme-Sliding Mechanism for Control of Ligand Affinity Proc.Natl.Acad.Sci.USA, 101, 2004
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1Q1F
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![BU of 1q1f by Molmil](/molmil-images/mine/1q1f) | Crystal structure of murine neuroglobin | Descriptor: | Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Vallone, B, Nienhaus, K, Matthes, K, Brunori, M, Nienhaus, G.U. | Deposit date: | 2003-07-19 | Release date: | 2004-06-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The structure of murine neuroglobin: Novel pathways for ligand migration and binding. Proteins, 56, 2004
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1F63
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![BU of 1f63 by Molmil](/molmil-images/mine/1f63) | CRYSTAL STRUCTURE OF DEOXY SPERM WHALE MYOGLOBIN MUTANT Y(B10)Q(E7)R(E10) | Descriptor: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Brunori, M, Cutruzzola, F, Savino, C, Travaglini-Allocatelli, C, Vallone, B, Gibson, Q.H. | Deposit date: | 2000-06-20 | Release date: | 2000-07-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural dynamics of ligand diffusion in the protein matrix: A study on a new myoglobin mutant Y(B10) Q(E7) R(E10). Biophys.J., 76, 1999
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1F65
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![BU of 1f65 by Molmil](/molmil-images/mine/1f65) | CRYSTAL STRUCTURE OF OXY SPERM WHALE MYOGLOBIN MUTANT Y(B10)Q(E7)R(E10) | Descriptor: | MYOGLOBIN, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Brunori, M, Cutruzzola, F, Savino, C, Travaglini-Allocatelli, C, Vallone, B, Gibson, Q.H. | Deposit date: | 2000-06-20 | Release date: | 2000-07-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural dynamics of ligand diffusion in the protein matrix: A study on a new myoglobin mutant Y(B10) Q(E7) R(E10). Biophys.J., 76, 1999
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6XUV
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![BU of 6xuv by Molmil](/molmil-images/mine/6xuv) | Crystallographic structure of oligosaccharide dehydrogenase from Pycnoporus cinnabarinus, laminaribiose-bound form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Cerutti, G, Savino, C, Montemiglio, L.C, Vallone, B, Sciara, G. | Deposit date: | 2020-01-21 | Release date: | 2021-02-03 | Last modified: | 2021-08-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure and functional characterization of an oligosaccharide dehydrogenase from Pycnoporus cinnabarinus provides insights into fungal breakdown of lignocellulose. Biotechnol Biofuels, 14, 2021
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6RA6
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![BU of 6ra6 by Molmil](/molmil-images/mine/6ra6) | Ferric murine neuroglobin Gly-loop44-47/F106A mutant | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Exertier, C, Freda, I, Montemiglio, L.C, Savino, C, Vallone, B. | Deposit date: | 2019-04-05 | Release date: | 2020-03-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Lack of orientation selectivity of the heme insertion in murine neuroglobin revealed by resonance Raman spectroscopy. Febs J., 287, 2020
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7OHD
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![BU of 7ohd by Molmil](/molmil-images/mine/7ohd) | CRYSTAL STRUCTURE OF FERRIC MURINE NEUROGLOBIN CDLESS MUTANT | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Exertier, C, Freda, I, Montemiglio, L.C, Savino, C, Cerutti, G, Gugole, E, Vallone, B. | Deposit date: | 2021-05-10 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Probing the Role of Murine Neuroglobin CDloop-D-Helix Unit in CO Ligand Binding and Structural Dynamics. Acs Chem.Biol., 17, 2022
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4XE3
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![BU of 4xe3 by Molmil](/molmil-images/mine/4xe3) | OleP, the cytochrome P450 epoxidase from Streptomyces antibioticus involved in Oleandomycin biosynthesis: functional analysis and crystallographic structure in complex with clotrimazole. | Descriptor: | 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE, Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Montemiglio, L.C, Parisi, G, Scaglione, A, Savino, C, Vallone, B. | Deposit date: | 2014-12-22 | Release date: | 2015-11-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Functional analysis and crystallographic structure of clotrimazole bound OleP, a cytochrome P450 epoxidase from Streptomyces antibioticus involved in oleandomycin biosynthesis. Biochim.Biophys.Acta, 1860, 2015
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1MZ0
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![BU of 1mz0 by Molmil](/molmil-images/mine/1mz0) | STRUCTURE OF MYOGLOBIN MB-YQR 316 ns AFTER PHOTOLYSIS OF CARBON MONOXIDE SOLVED FROM LAUE DATA AT RT. | Descriptor: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Bourgeois, D, Vallone, B, Schotte, F, Arcovito, A, Miele, A.E, Sciara, G, Wulff, M, Anfinrud, P, Brunori, M. | Deposit date: | 2002-10-04 | Release date: | 2003-07-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Complex landscape of protein structural dynamics unveiled by
nanosecond Laue crystallography. Proc.Natl.Acad.Sci.USA, 100, 2003
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1MYZ
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![BU of 1myz by Molmil](/molmil-images/mine/1myz) | CO COMPLEX OF MYOGLOBIN MB-YQR AT RT SOLVED FROM LAUE DATA. | Descriptor: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Bourgeois, D, Vallone, B, Schotte, F, Arcovito, A, Miele, A.E, Sciara, G, Wulff, M, Anfinrud, P, Brunori, M. | Deposit date: | 2002-10-04 | Release date: | 2003-08-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Complex landscape of protein
structural dynamics unveiled by
nanosecond Laue crystallography. Proc.Natl.Acad.Sci.USA, 100, 2003
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1N5Q
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![BU of 1n5q by Molmil](/molmil-images/mine/1n5q) | Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with dehydrated Sancycline | Descriptor: | 4-DIMETHYLAMINO-1,10,11,12-TETRAHYDROXY-3-OXO-3,4,4A,5-TETRAHYDRO-NAPHTHACENE-2-CARBOXYLIC ACID AMIDE, ActaVA-Orf6 monooxygenase, HEXAETHYLENE GLYCOL | Authors: | Sciara, G, Kendrew, S.G, Miele, A.E, Marsh, N.G, Federici, L, Malatesta, F, Schimperna, G, Savino, C, Vallone, B. | Deposit date: | 2002-11-07 | Release date: | 2003-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis Embo J., 22, 2003
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1N5S
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![BU of 1n5s by Molmil](/molmil-images/mine/1n5s) | Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with the ligand Acetyl Dithranol | Descriptor: | (1,8-DIHYDROXY-9-OXO-9,10-DIHYDRO-ANTHRACEN-2-YL)-ACETIC ACID, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ActVA-Orf6 monooxygenase | Authors: | Sciara, G, Kendrew, S.G, Miele, A.E, Marsh, N.G, Federici, L, Malatesta, F, Schimperna, G, Savino, C, Vallone, B. | Deposit date: | 2002-11-07 | Release date: | 2003-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The structure of ActVA-Orf6, a novel type of monooxygenase involved in
actinorhodin biosynthesis Embo J., 22, 2003
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1N5T
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![BU of 1n5t by Molmil](/molmil-images/mine/1n5t) | Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with the ligand Oxidized Acetyl Dithranol | Descriptor: | (1,8-DIHYDROXY-9,10-DIOXO-9,10-DIHYDRO-ANTHRACEN-2-YL)-ACETIC ACID, ActVA-Orf6 monooxygenase | Authors: | Sciara, G, G Kendrew, S, Miele, A.E, Marsh, N.G, Federici, L, Malatesta, F, Schimperna, G, Savino, C, Vallone, B. | Deposit date: | 2002-11-07 | Release date: | 2003-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structure of ActVA-Orf6, a novel type of monooxygenase involved in
actinorhodin biosynthesis Embo J., 22, 2003
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1N5V
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![BU of 1n5v by Molmil](/molmil-images/mine/1n5v) | Crystal structure of a Monooxygenase from the gene ActVA-Orf6 of Streptomyces coelicolor in complex with the ligand Nanaomycin D | Descriptor: | 7-HYDROXY-5-METHYL-3,3A,5,11B-TETRAHYDRO-1,4-DIOXA-CYCLOPENTA[A]ANTHRACENE-2,6,11-TRIONE, ActVA-Orf6 monooxygenase | Authors: | Sciara, G, Kendrew, S.G, Miele, A.E, Marsh, N.G, Federici, L, Malatesta, F, Schimperna, G, Savino, C, Vallone, B. | Deposit date: | 2002-11-07 | Release date: | 2003-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | The structure of ActVA-Orf6, a novel type of monooxygenase involved in
actinorhodin biosynthesis Embo J., 22, 2003
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1GLI
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![BU of 1gli by Molmil](/molmil-images/mine/1gli) | |
7Q6R
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![BU of 7q6r by Molmil](/molmil-images/mine/7q6r) | OleP mutant E89Y in complex with 6DEB | Descriptor: | 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, FORMIC ACID, ... | Authors: | Savino, C, Montemiglio, L.C, Vallone, B, Exertier, C, Freda, I, Gugole, E. | Deposit date: | 2021-11-09 | Release date: | 2022-01-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics. Biomolecules, 12, 2021
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7Q89
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![BU of 7q89 by Molmil](/molmil-images/mine/7q89) | OleP mutant G92W in complex with 6DEB | Descriptor: | 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, FORMIC ACID, ... | Authors: | Savino, C, Montemiglio, L.C, Vallone, B, Exertier, C, Freda, I, Gugole, E. | Deposit date: | 2021-11-10 | Release date: | 2022-01-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics. Biomolecules, 12, 2021
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7Q6X
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![BU of 7q6x by Molmil](/molmil-images/mine/7q6x) | OleP mutant S240Y in complex with 6DEB | Descriptor: | 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, FORMIC ACID, ... | Authors: | Savino, C, Montemiglio, L.C, Vallone, B, Exertier, C, Freda, I, Gugole, E. | Deposit date: | 2021-11-09 | Release date: | 2022-01-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics. Biomolecules, 12, 2021
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3ZKP
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![BU of 3zkp by Molmil](/molmil-images/mine/3zkp) | |
7ZPA
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![BU of 7zpa by Molmil](/molmil-images/mine/7zpa) | Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the closed conformation, C1 symmetry | Descriptor: | DNA (48-MER), PLP-dependent aminotransferase family protein | Authors: | Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Exertier, C, Savino, C, Chaves Sanjuan, A, Bolognesi, M. | Deposit date: | 2022-04-27 | Release date: | 2023-07-05 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR. Nucleic Acids Res., 51, 2023
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7ZLA
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![BU of 7zla by Molmil](/molmil-images/mine/7zla) | Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the half-closed conformation | Descriptor: | DNA (48-MER), PLP-dependent aminotransferase family protein | Authors: | Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Savino, C, Exertier, C, Bolognesi, M, Chaves Sanjuan, A. | Deposit date: | 2022-04-14 | Release date: | 2023-07-05 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.99 Å) | Cite: | Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR. Nucleic Acids Res., 51, 2023
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7ZN5
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![BU of 7zn5 by Molmil](/molmil-images/mine/7zn5) | Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the closed conformation, C2 symmetry. | Descriptor: | DNA (48-MER), PLP-dependent aminotransferase family protein | Authors: | Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Exertier, C, Savino, C, Chaves Sanjuan, A, Bolognesi, M. | Deposit date: | 2022-04-20 | Release date: | 2023-07-05 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR. Nucleic Acids Res., 51, 2023
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7ZTH
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![BU of 7zth by Molmil](/molmil-images/mine/7zth) | Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the open conformation | Descriptor: | DNA (48-MER), PLP-dependent aminotransferase family protein | Authors: | Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Exertier, C, Savino, C, Chaves Sanjuan, A, Bolognesi, M. | Deposit date: | 2022-05-10 | Release date: | 2023-07-05 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR. Nucleic Acids Res., 51, 2023
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6ZHZ
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![BU of 6zhz by Molmil](/molmil-images/mine/6zhz) | OleP-oleandolide(DEO) in high salt crystallization conditions | Descriptor: | (3~{R},4~{S},5~{R},6~{S},7~{S},9~{S},11~{R},12~{S},13~{R},14~{R})-3,5,7,9,11,13,14-heptamethyl-4,6,12-tris(oxidanyl)-1-oxacyclotetradecane-2,10-dione, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytochrome P-450, ... | Authors: | Montemiglio, L.C, Savino, C, Vallone, B, Parisi, G, Cecchetti, C. | Deposit date: | 2020-06-24 | Release date: | 2020-10-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate. Biomolecules, 10, 2020
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