7NLG
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7NLI
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7NLH
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3U1N
| Structure of the catalytic core of human SAMHD1 | Descriptor: | PHOSPHATE ION, SAM domain and HD domain-containing protein 1, ZINC ION | Authors: | Goldstone, D.C, Ennis-Adeniran, V, Walker, P.A, Haire, L.F, Webb, M, Taylor, I.A. | Deposit date: | 2011-09-30 | Release date: | 2011-11-16 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase Nature, 480, 2011
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8COO
| Solution structure of Zipcode binding protein 1 (ZBP1) KH3(DD)KH4 domains in complex with N6-Methyladenosine containing RNA | Descriptor: | Insulin-like growth factor 2 mRNA-binding protein 1, RNA_(5'-R(*(UP*CP*GP*GP*(6MZ)P*CP*U)-3') | Authors: | Nicastro, G, Abis, G, Taylor, I.A, Ramos, A. | Deposit date: | 2023-02-28 | Release date: | 2024-02-07 | Method: | SOLUTION NMR | Cite: | Direct m6A recognition by IMP1 underlays an alternative model of target selection for non-canonical methyl-readers. Nucleic Acids Res., 51, 2023
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6XU1
| Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dAMPNPP and Mg | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | Deposit date: | 2020-01-17 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis. Nat Commun, 11, 2020
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6YOM
| Crystal structure of tetrameric human D137N-SAMHD1 (residues 109-626) with XTP, dATP, dCMPNPP, Mn and Mg | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | Deposit date: | 2020-04-14 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis. Nat Commun, 11, 2020
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2X1A
| Structure of Rna15 RRM with RNA bound (G) | Descriptor: | 5'-R(*GP*UP*UP*GP*UP)-3', MAGNESIUM ION, MRNA 3'-END-PROCESSING PROTEIN RNA15 | Authors: | Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A. | Deposit date: | 2010-01-06 | Release date: | 2010-02-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors. Nucleic Acids Res., 38, 2010
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2X1F
| Structure of Rna15 RRM with bound RNA (GU) | Descriptor: | 5'-R(*GP*UP*UP*GP*UP)-3', MRNA 3'-END-PROCESSING PROTEIN RNA15 | Authors: | Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A. | Deposit date: | 2010-01-06 | Release date: | 2010-02-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors. Nucleic Acids Res., 38, 2010
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1G6G
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6QEY
| IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties | Descriptor: | ACETONITRILE, Insulin-like growth factor 2 mRNA-binding protein 1, PHOSPHATE ION | Authors: | Dagil, R, Ball, N.J, Ogrodowicz, R.W, Purkiss, A.G, Taylor, I.A, Ramos, A. | Deposit date: | 2019-01-09 | Release date: | 2019-03-27 | Last modified: | 2019-09-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties. Nucleic Acids Res., 47, 2019
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6SAI
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6S7X
| dARC1 capsid domain dimer, orthorhombic form at 1.7 Angstrom | Descriptor: | Activity-regulated cytoskeleton associated protein 1, CHLORIDE ION, SODIUM ION | Authors: | Cottee, M.A, Taylor, I.A. | Deposit date: | 2019-07-07 | Release date: | 2020-01-15 | Last modified: | 2020-01-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure ofDrosophila melanogasterARC1 reveals a repurposed molecule with characteristics of retroviral Gag. Sci Adv, 6, 2020
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6SSM
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6S7Y
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6SSK
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6SSL
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6SA9
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6SSJ
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2NPI
| Clp1-ATP-Pcf11 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein CLP1, ... | Authors: | Noble, C.G, Beuth, B, Taylor, I.A. | Deposit date: | 2006-10-27 | Release date: | 2006-12-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor Nucleic Acids Res., 35, 2007
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4UX5
| Structure of DNA complex of PCG2 | Descriptor: | 5'-D(*CP*AP*AP*TP*GP*AP*CP*GP*CP*GP*TP*AP*AP*GP)-3', 5'-D(*CP*TP*TP*AP*CP*GP*CP*GP*TP*CP*AP*TP*TP*GP)-3', TRANSCRIPTION FACTOR MBP1 | Authors: | Liu, J, Huang, J, Zhao, Y, Liu, H, Wang, D, Yang, J, Zhao, W, Taylor, I.A, Peng, Y. | Deposit date: | 2014-08-19 | Release date: | 2015-01-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis of DNA Recognition by Pcg2 Reveals a Novel DNA Binding Mode for Winged Helix-Turn-Helix Domains. Nucleic Acids Res., 43, 2015
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3BP9
| Structure of B-tropic MLV capsid N-terminal domain | Descriptor: | GLYCEROL, Gag protein, ISOPROPYL ALCOHOL | Authors: | Gulnahar, M.B, Dodding, M.P, Goldstone, D.C, Haire, L.F, Stoye, J.P, Taylor, I.A. | Deposit date: | 2007-12-18 | Release date: | 2008-02-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, gag assembly and core formation J.Mol.Biol., 376, 2008
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2BF0
| crystal structure of the rpr of pcf11 | Descriptor: | CALCIUM ION, PCF11 | Authors: | Noble, C.G, Hollingworth, D, Martin, S.R, Adeniran, V.E, Smerdon, S.J, Kelly, G, Taylor, I.A, Ramos, A. | Deposit date: | 2004-12-02 | Release date: | 2005-01-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Key Features of the Interaction between Pcf11 Cid and RNA Polymerase II Ctd. Nat.Struct.Mol.Biol., 12, 2005
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2ASB
| Structure of a Mycobacterium tuberculosis NusA-RNA complex | Descriptor: | Transcription elongation protein nusA, ribosomal RNA (5'- GAACUCAAUAG -3') | Authors: | Beuth, B, Pennell, S, Arnvig, K.B, Martin, S.R, Taylor, I.A. | Deposit date: | 2005-08-23 | Release date: | 2005-10-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of a Mycobacterium tuberculosis NusA-RNA complex. Embo J., 24, 2005
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2ATW
| Structure of a Mycobacterium tuberculosis NusA-RNA complex | Descriptor: | Transcription elongation protein nusA, ribosomal RNA (5'- AGAACUCAAUAG -3') | Authors: | Beuth, B, Pennell, S, Arnvig, K.B, Martin, S.R, Taylor, I.A. | Deposit date: | 2005-08-26 | Release date: | 2005-10-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure of a Mycobacterium tuberculosis NusA-RNA complex. Embo J., 24, 2005
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