4M43
 
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5U64
 | | Camel nanobody VHH-28 | | Descriptor: | VHH-28 | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2016-12-07 | | Release date: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (1.153 Å) | | Cite: | Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers.
Sci Rep, 7, 2017
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7LVS
 | | The CBP TAZ1 Domain in Complex with a CITED2-HIF-1-Alpha Fusion Peptide | | Descriptor: | Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha, Histone lysine acetyltransferase CREBBP, ZINC ION | | Authors: | Appling, F.D, Berlow, R.B, Stanfield, R.L, Dyson, H.J, Wright, P.E. | | Deposit date: | 2021-02-26 | | Release date: | 2021-07-28 | | Last modified: | 2021-12-15 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | The molecular basis of allostery in a facilitated dissociation process.
Structure, 29, 2021
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7U04
 | | IOMA class antibody ACS101 | | Descriptor: | GLYCEROL, IOMA class antibody ACS101 heavy chain, IOMA class antibody ACS101 light chain | | Authors: | Farokhi, E, Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2022-02-17 | | Release date: | 2022-08-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.
Nat Commun, 13, 2022
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7U0K
 | | IOMA class antibody Fab ACS124 | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, IOMA Class antibody ACS124 Heavy chain, IOMA Class antibody ACS124 Light chain | | Authors: | Farokhi, E, Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2022-02-18 | | Release date: | 2022-08-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.
Nat Commun, 13, 2022
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3C2A
 | | Antibody Fab fragment 447-52D in complex with UG1033 peptide | | Descriptor: | Envelope glycoprotein, Fab 447-52D heavy chain, Fab 447-52D light chain | | Authors: | Dhillon, A.K, Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2008-01-24 | | Release date: | 2008-07-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure determination of an anti-HIV-1 Fab 447-52D-peptide complex from an epitaxially twinned data set
Acta Crystallogr.,Sect.D, 64, 2008
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7U5G
 | | ACS122 Fab | | Descriptor: | ACS122 Fab Heavy chain, ACS122 Fab Light chain | | Authors: | Farokhi, E, Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2022-03-02 | | Release date: | 2022-11-02 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer.
Plos Pathog., 18, 2022
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1W72
 | | Crystal structure of HLA-A1:MAGE-A1 in complex with Fab-Hyb3 | | Descriptor: | BETA-2-MICROGLOBULIN, GLYCEROL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | | Authors: | Hulsmeyer, M, Chames, P, Hillig, R.C, Stanfield, R.L, Held, G, Coulie, P.G, Alings, C, Wille, G, Saenger, W, Uchanska-Ziegler, B, Hoogenboom, H.R, Ziegler, A. | | Deposit date: | 2004-08-27 | | Release date: | 2004-11-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | A Major Histocompatibility Complex.Peptide- Restricted Antibody and T Cell Receptor Molecules Recognize Their Target by Distinct Binding Modes: Crystal Structure of Human Leukocyte Antigen (Hla)-A1.Mage-A1 in Complex with Fab-Hyb3
J.Biol.Chem., 280, 2005
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6UNA
 | | Crystal structure of inactive p38gamma | | Descriptor: | GLYCEROL, Mitogen-activated protein kinase 12, SULFATE ION | | Authors: | Aoto, P.C, Stanfield, R.L, Wilson, I.A, Dyson, H.J, Wright, P.E. | | Deposit date: | 2019-10-11 | | Release date: | 2019-12-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.554 Å) | | Cite: | A Dynamic Switch in Inactive p38 gamma Leads to an Excited State on the Pathway to an Active Kinase.
Biochemistry, 58, 2019
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6V8U
 | | Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a modified Kaiso binding sequence (KBS) | | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*CP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*GP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ... | | Authors: | Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E. | | Deposit date: | 2019-12-12 | | Release date: | 2020-04-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.103 Å) | | Cite: | A Conformational Switch in the Zinc Finger Protein Kaiso Mediates Differential Readout of Specific and Methylated DNA Sequences.
Biochemistry, 59, 2020
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6X1W
 | | Structure of pHis Fab (SC56-2) in complex with pHis mimetic peptide | | Descriptor: | ACLYana-3-pTza peptide, SC56-2 Heavy chain, SC56-2 Light chain | | Authors: | Kalagiri, R, Stanfield, R, Wilson, I.A, Hunter, T. | | Deposit date: | 2020-05-19 | | Release date: | 2021-02-03 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6X1U
 | | Structure of pHis Fab (SC39-4) in complex with pHis mimetic peptide | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ACLYana-3-pTza peptide, ... | | Authors: | Kalagiri, R, Stanfield, R, Wilson, I.A, Hunter, T. | | Deposit date: | 2020-05-19 | | Release date: | 2021-02-03 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.641 Å) | | Cite: | Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6X1V
 | | Structure of pHis Fab (SC44-8) in complex with pHis mimetic peptide | | Descriptor: | 1,2-ETHANEDIOL, ACLYana-3-pTza peptide, SC44-8 Heavy chain, ... | | Authors: | Kalagiri, R, Stanfield, R, Wilson, I.A, Hunter, T. | | Deposit date: | 2020-05-19 | | Release date: | 2021-02-03 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 118, 2021
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2QSC
 | | Crystal structure analysis of anti-HIV-1 V3-Fab F425-B4e8 in complex with a V3-peptide | | Descriptor: | CHLORIDE ION, Envelope glycoprotein gp120, Fab F425-B4e8, ... | | Authors: | Bell, C.H, Schiefner, A, Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2007-07-30 | | Release date: | 2008-01-15 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization.
J.Mol.Biol., 375, 2008
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2OQJ
 | | Crystal structure analysis of Fab 2G12 in complex with peptide 2G12.1 | | Descriptor: | Fab 2G12 heavy chain, Fab 2G12 light chain, peptide 2G12.1 (ACPPSHVLDMRSGTCLAAEGK) | | Authors: | Calarese, D.A, Stanfield, R.L, Menendez, A, Scott, J.K, Wilson, I.A. | | Deposit date: | 2007-01-31 | | Release date: | 2008-01-15 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120.
Faseb J., 22, 2008
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3K6T
 | | Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans at 2.04 A resolution | | Descriptor: | Female germline-specific tumor suppressor gld-1 | | Authors: | Beuck, C, Szymczyna, B.R, Kerkow, D.E, Carmel, A.B, Columbus, L, Stanfield, R.L, Williamson, J.R. | | Deposit date: | 2009-10-09 | | Release date: | 2010-03-09 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation.
Structure, 18, 2010
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3KBL
 | | Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans N169A mutant at 2.28 A resolution | | Descriptor: | Female germline-specific tumor suppressor gld-1 | | Authors: | Beuck, C, Szymczyna, B.R, Kerkow, D.E, Carmel, A.B, Columbus, L, Stanfield, R.L, Williamson, J.R. | | Deposit date: | 2009-10-20 | | Release date: | 2010-03-09 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Structure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation.
Structure, 18, 2010
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1TZG
 | | Crystal structure of HIV-1 neutralizing human Fab 4E10 in complex with a 13-residue peptide containing the 4E10 epitope on gp41 | | Descriptor: | Envelope polyprotein GP160, Fab 4E10, GLYCEROL | | Authors: | Cardoso, R.M.F, Zwick, M.B, Stanfield, R.L, Kunert, R, Binley, J.M, Katinger, H, Burton, D.R, Wilson, I.A. | | Deposit date: | 2004-07-09 | | Release date: | 2005-03-01 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Broadly Neutralizing Anti-HIV Antibody 4E10 Recognizes a Helical Conformation of a Highly Conserved Fusion-Associated Motif in gp41
Immunity, 22, 2005
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6X1S
 | | Structure of pHis Fab (SC1-1) in complex with pHis mimetic peptide | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, NM23-1-pTza peptide, SC1-1 Heavy chain, ... | | Authors: | Kalagiri, R, Stanfield, R.L, Wilson, I.A, Hunter, T. | | Deposit date: | 2020-05-19 | | Release date: | 2021-02-03 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6X1T
 | | Structure of pHis Fab (SC50-3) in complex with pHis mimetic peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Kalagiri, R, Stanfield, R.L, Wilson, I.A, Hunter, T. | | Deposit date: | 2020-05-19 | | Release date: | 2021-02-03 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Structural basis for differential recognition of phosphohistidine-containing peptides by 1-pHis and 3-pHis monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 118, 2021
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8T5X
 | | Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T) | | Descriptor: | Transthyretin | | Authors: | Ferguson, J.A, Sun, X, Leach, B.I, Stanfield, R.L, Dyson, H.J, Wright, P.E. | | Deposit date: | 2023-06-14 | | Release date: | 2023-08-02 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Probing the Dissociation Pathway of a Kinetically Labile Transthyretin Mutant.
J.Am.Chem.Soc., 146, 2024
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8W1N
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8W2W
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6BL6
 | | Crystallization of lipid A transporter MsbA from Salmonella typhimurium | | Descriptor: | Lipid A export ATP-binding/permease protein MsbA | | Authors: | Padayatti, P.S, Stanfield, R.L, Zhang, Q, Wilson, I.A, Lee, S.C. | | Deposit date: | 2017-11-09 | | Release date: | 2019-01-09 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Insights into the Lipid A Transport Pathway in MsbA.
Structure, 27, 2019
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4F6N
 | | Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA | | Descriptor: | DNA (5'-D(*CP*GP*TP*AP*TP*AP*GP*AP*(5CM)P*GP*(5CM)P*GP*GP*TP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*AP*CP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*AP*TP*AP*CP*G)-3'), GLYCEROL, ... | | Authors: | Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E. | | Deposit date: | 2012-05-15 | | Release date: | 2012-09-05 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
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